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Cells can be considered as systems that utilize changes in thermodynamic entropy as information. Therefore, they serve as useful models for investigating the relationships between entropy production and information transmission, i.e.,…

Molecular Networks · Quantitative Biology 2017-03-09 Tatsuaki Tsuruyama

Membrane protein transporters alternate their substrate-binding sites between the extracellular and cytosolic side of the membrane according to the alternating access mechanism. Inspired by this intriguing mechanism devised by nature, we…

Biological Physics · Physics 2017-11-08 Yizhou Tan , Leonardo Dagdug , Jannes Gladrow , Ulrich F. Keyser , Stefano Pagliara

Molecular motor proteins serve as an essential component of intracellular transport by generating forces to haul cargoes along cytoskeletal filaments. Two species of motors that are directed oppositely (e.g. kinesin, dynein) can be attached…

Subcellular Processes · Quantitative Biology 2017-05-10 Christopher E. Miles , James P. Keener

This paper studies the impact of a transmitter's molecule generation process on the capacity of a concentration based Molecular Communication (MC) system. Constraints caused by the molecule generation process affect the availability of the…

Information Theory · Computer Science 2018-02-27 Hamid G. Bafghi , Amin Gohari , Mahtab Mirmohseni , Masoumeh Nasiri-Kenari

To explain the differentiation of stem cells in terms of dynamical systems theory, models of interacting cells with intracellular protein expression dynamics are analyzed and simulated. Simulations were carried out for all possible protein…

Cell Behavior · Quantitative Biology 2015-06-15 Yusuke Goto , Kunihiko Kaneko

Cells sense external concentrations and, via biochemical signaling, respond by regulating the expression of target proteins. Both in signaling networks and gene regulation there are two main mechanisms by which the concentration can be…

Subcellular Processes · Quantitative Biology 2017-04-12 Gabriele Micali , Gerardo Aquino , David M. Richards , Robert G. Endres

Recent empirical studies have confirmed the key roles of complex contagion mechanisms such as memory, social reinforcement, and decay effects in information diffusion and behaviour spreading. Inspired by this fact, we here propose a new…

Physics and Society · Physics 2014-08-20 Pengbi Cui , Ming Tang , Zhi-Xi Wu

Many foraging microorganisms rely upon cellular transport networks to deliver nutrients, fluid and organelles between different parts of the organism. Networked organisms ranging from filamentous fungi to slime molds demonstrate a…

Adaptation and Self-Organizing Systems · Physics 2020-12-08 Cassidy Mentus , Marcus Roper

Molecular diffusion measurements are widely used to probe microstructure in materials and living organisms noninvasively. The precise relation of diffusion metrics to microstructure remains a major challenge: In complex samples, it is often…

Biological Physics · Physics 2014-04-15 Dmitry S. Novikov , Els Fieremans , Jens H. Jensen , Joseph A. Helpern

This paper considers an electro-chemical based communication model for intercellular communication in plants. Many plants, such as Mimosa pudica (the "sensitive plant"), employ electrochemical signals known as action potentials (APs) for…

Neurons and Cognition · Quantitative Biology 2019-04-05 Hamdan Awan , Raviraj S. Adve , Nigel Wallbridge , Carrol Plummer , Andrew W. Eckford

In diffusion-based communication, as for molecular systems, the achievable data rate is very low due to the slow nature of diffusion and the existence of severe inter-symbol interference (ISI). Multiple-input multiple-output (MIMO)…

Information Theory · Computer Science 2018-01-23 S. Mohammadreza Rouzegar , Umberto Spagnolini

In this paper, we consider a molecular diffusion based communications link that can reliably transport data over-the-air. We show that the system can also reliably transport data across confined structural environments, especially in cases…

Emerging Technologies · Computer Science 2014-03-28 Song Qiu , Weisi Guo , Siyi Wang , Nariman Farsad , Andrew Eckford

This work presents a comprehensive performance analysis of diffusion based direct, dual-hop, and multi-hop molecular communication systems with Brownian motion and drift in the presence of various distortions such as inter-symbol…

Information Theory · Computer Science 2017-10-03 Neeraj Varshney , Adarsh Patel , Aditya K. Jagannatham , Pramod K. Varshney

In this work, we consider diffusion-based molecular communication with and without drift between two static nano-machines. We employ type-based information encoding, releasing a single molecule per information bit. At the receiver, we…

Information Theory · Computer Science 2018-07-13 Werner Haselmayr , Neeraj Varshney , A. Taufiq Asyhari , Andreas Springer , Weisi Guo

Feedback in sensory biochemical networks can give rise to bifurcations in cells' behavioral response. These bifurcations share many properties with thermodynamic critical points. Evidence suggests that biological systems may operate near…

Biological Physics · Physics 2020-12-04 Michael Vennettilli , Amir Erez , Andrew Mugler

In this paper, we apply dimensional analysis to study a diffusive molecular communication system that uses diffusing enzymes in the propagation environment to mitigate intersymbol interference. The enzymes bind to information molecules and…

Information Theory · Computer Science 2013-11-21 Adam Noel , Karen C. Cheung , Robert Schober

In this paper, we propose novel modulation techniques using isomers as messenger molecules for nano communication via diffusion. To evaluate achievable rate performance, we compare the proposed techniques with concentration-based and…

Quantitative Methods · Quantitative Biology 2012-01-05 Na-Rae Kim , Chan-Byoung Chae

The combination of protrusions and retractions in the movement of polarized cells leads to understand the effect of possible synchronisation between the two ends of the cells. This synchronisation, in turn, could lead to different dynamics…

Cell Behavior · Quantitative Biology 2021-09-21 Gissell Estrada-Rodriguez , Benoit Perthame

The processes responsible for the effective longitudinal transport of solar energetic particles (SEPs) are still not completely understood. We address this issue by simulating SEP electron propagation using a spatially 2D transport model…

Solar and Stellar Astrophysics · Physics 2018-04-12 R. D. Strauss , N. Dresing , N. E. Engelbrecht

Molecular communication is a biologically-inspired method of communication with attractive properties for microscale and nanoscale devices. In molecular communication, messages are transmitted by releasing a pattern of molecules at a…

Information Theory · Computer Science 2008-12-09 Andrew W. Eckford
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