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Deep learning has shown outstanding performance in identifying intricate structures in complex high-dimensional data, especially in the domain of computer vision. The application of deep learning to early detection and automated…

Image and Video Processing · Electrical Eng. & Systems 2019-08-22 Taeho Jo , Kwangsik Nho , Andrew J. Saykin

High-dimensional phenotypes hold promise for richer findings in association studies, but testing of several phenotype traits aggravates the grand challenge of association studies, that of multiple testing. Several methods have recently been…

Methodology · Statistics 2013-05-14 Pekka Marttinen , Jussi Gillberg , Aki Havulinna , Jukka Corander , Samuel Kaski

Canonical Correlation Analysis (CCA) is a method for analyzing pairs of random vectors; it learns a sequence of paired linear transformations such that the resultant canonical variates are maximally correlated within pairs while…

Methodology · Statistics 2023-08-23 Daniel Kessler , Elizaveta Levina

Background and Objective: Given the high heterogeneity and clinical diversity of cancer, substantial variations exist in multi-omics data and clinical features across different cancer subtypes. Methods: We propose a model, named DEDUCE,…

Machine Learning · Computer Science 2024-10-29 Liangrui Pan , Xiang Wang , Qingchun Liang , Jiandong Shang , Wenjuan Liu , Liwen Xu , Shaoliang Peng

In cancer research, profiling studies have been extensively conducted, searching for genes/SNPs associated with prognosis. Cancer is a heterogeneous disease. Examining similarity and difference in the genetic basis of multiple subtypes of…

Methodology · Statistics 2013-04-18 Jin Liu , Jian Huang , Yawei Zhang , Qing Lan , Nathaniel Rothman , Tongzhang Zheng , Shuangge Ma

Canonical correlation analysis (CCA) is a state-of-the-art method for frequency recognition in steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI) systems. Various extended methods have been developed, and…

Neurons and Cognition · Quantitative Biology 2018-07-03 Yangsong Zhang , Erwei Yin , Fali Li , Yu Zhang , Toshihisa Tanaka , Qibin Zhao , Yan Cui , Peng Xu , Dezhong Yao , Daqing Guo

We examine Deep Canonically Correlated LSTMs as a way to learn nonlinear transformations of variable length sequences and embed them into a correlated, fixed dimensional space. We use LSTMs to transform multi-view time-series data…

Machine Learning · Statistics 2018-01-17 Neil Mallinar , Corbin Rosset

Finding relationships between multiple views of data is essential both for exploratory analysis and as pre-processing for predictive tasks. A prominent approach is to apply variants of Canonical Correlation Analysis (CCA), a classical…

Machine Learning · Statistics 2016-01-11 Ziyuan Lin , Jaakko Peltonen

Canonical correlation analysis is a statistical technique that is used to find relations between two sets of variables. An important extension in pattern analysis is to consider more than two sets of variables. This problem can be expressed…

Machine Learning · Computer Science 2013-02-06 Jan Rupnik , Primoz Skraba , John Shawe-Taylor , Sabrina Guettes

Most multi-view clustering methods are limited by shallow models without sound nonlinear information perception capability, or fail to effectively exploit complementary information hidden in different views. To tackle these issues, we…

Machine Learning · Computer Science 2022-10-14 Fu Lele , Zhang Lei , Yang Jinghua , Chen Chuan , Zhang Chuanfu , Zheng Zibin

Cortical pyramidal neurons receive inputs from multiple distinct neural populations and integrate these inputs in separate dendritic compartments. We explore the possibility that cortical microcircuits implement Canonical Correlation…

Neurons and Cognition · Quantitative Biology 2021-03-29 David Lipshutz , Yanis Bahroun , Siavash Golkar , Anirvan M. Sengupta , Dmitri B. Chklovskii

Various new brain-computer interface technologies or neuroscience applications require decoding stimulus-following neural responses to natural stimuli such as speech and video from, e.g., electroencephalography (EEG) signals. In this…

Signal Processing · Electrical Eng. & Systems 2024-08-01 Simon Geirnaert , Yuanyuan Yao , Tom Francart , Alexander Bertrand

Describing the dimension reduction (DR) techniques by means of probabilistic models has recently been given special attention. Probabilistic models, in addition to a better interpretability of the DR methods, provide a framework for further…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Mehran Safayani , Saeid Momenzadeh

Generalized correlation analysis (GCA) is concerned with uncovering linear relationships across multiple datasets. It generalizes canonical correlation analysis that is designed for two datasets. We study sparse GCA when there are…

Machine Learning · Statistics 2023-02-07 Sheng Gao , Zongming Ma

Linear discriminant analysis (LDA) is a fundamental method for feature extraction and dimensionality reduction. Despite having many variants, classical LDA has its own importance, as it is a keystone in human knowledge about statistical…

Computer Vision and Pattern Recognition · Computer Science 2022-10-03 Sayed Kamaledin Ghiasi-Shirazi

Conventional and deep learning-based methods have shown great potential in the medical imaging domain, as means for deriving diagnostic, prognostic, and predictive biomarkers, and by contributing to precision medicine. However, these…

This paper studies high-dimensional canonical correlation analysis (CCA) with an emphasis on the vectors that define canonical variables. The paper shows that when two dimensions of data grow to infinity jointly and proportionally, the…

Econometrics · Economics 2025-01-24 Anna Bykhovskaya , Vadim Gorin

Proteins have evolved to perform diverse cellular functions, from serving as reaction catalysts to coordinating cellular propagation and development. Frequently, proteins do not exert their full potential as monomers but rather undergo…

Biomolecules · Quantitative Biology 2019-10-07 Guido Uguzzoni , Shalini John Lovis , Francesco Oteri , Alexander Schug , Hendrik Szurmant , Martin Weigt

Comparing different neural network representations and determining how representations evolve over time remain challenging open questions in our understanding of the function of neural networks. Comparing representations in neural networks…

Machine Learning · Statistics 2018-10-25 Ari S. Morcos , Maithra Raghu , Samy Bengio

In the complex realm of cognitive disorders, Alzheimer's disease (AD) and vascular dementia (VaD) are the two most prevalent dementia types, presenting entangled symptoms yet requiring distinct treatment approaches. The crux of effective…

Image and Video Processing · Electrical Eng. & Systems 2024-11-08 Salma Hassan , Dawlat Akaila , Maryam Arjemandi , Vijay Papineni , Mohammad Yaqub