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There is increasing evidence for specific cortical and subcortical large-scale human epileptic networks to be involved in the generation, spread, and termination of not only primary generalized but also focal onset seizures. The complex…

Neurons and Cognition · Quantitative Biology 2016-10-07 Christian Geier , Marie-Therese Kuhnert , Christian E. Elger , Klaus Lehnertz

Epilepsy is a chronic neurological disorder affecting more than 65 million people worldwide and manifested by recurrent unprovoked seizures. The unpredictability of seizures not only degrades the quality of life of the patients, but it can…

Signal Processing · Electrical Eng. & Systems 2019-11-13 Damian Pascual , Amir Aminifar , David Atienza , Philippe Ryvlin , Roger Wattenhofer

The resting-state brain networks (RSNs) reflects the functional connectivity patterns between brain modules, providing essential foundations for decoding intrinsic neural information within the brain. It serves as one of the primary tools…

Human-Computer Interaction · Computer Science 2025-01-22 Shiang Hu , Xiao Gong , Xiaolong Huang , Jie Ruan , Pedro Antonio Valdes-Sosa

Neural oscillations are considered to be brain-specific signatures of information processing and communication in the brain. They also reflect pathological brain activity in neurological disorders, thus offering a basis for diagnoses and…

Neurons and Cognition · Quantitative Biology 2023-10-23 Tena Dubcek , Debora Ledergerber , Jana Thomann , Giovanna Aiello , Marc Serra-Garcia , Lukas Imbach , Rafael Polania

Automatic classification of epileptic seizure types in electroencephalograms (EEGs) data can enable more precise diagnosis and efficient management of the disease. This task is challenging due to factors such as low signal-to-noise ratios,…

Machine Learning · Computer Science 2020-10-01 Umar Asif , Subhrajit Roy , Jianbin Tang , Stefan Harrer

Identifying preictal states -- periods during which seizures are more likely to occur -- remains a central challenge in clinical computational neuroscience. In this study, we introduce a novel framework that embeds functional brain…

Neurons and Cognition · Quantitative Biology 2025-05-21 Steven Rico-Aparicio , Martin Guillemaud , Alice Longhena , Vincent Navarro , Louis Cousyn , Mario Chavez

A seizure's electrographic dynamics are characterised by its spatiotemporal evolution, also termed dynamical "pathway" and the time it takes to complete that pathway, which results in the seizure's duration. Both seizure pathways and…

Epilepsy is a disease in which frequent seizures occur due to abnormal activity of neurons. Patients affected by this disease can be treated with the help of medicines or surgical procedures. However, both of these methods are not quite…

Neurons and Cognition · Quantitative Biology 2020-04-20 Syed Muhammad Usman , Shahzad Latif , Arshad Beg

Epileptic seizures detection and forecasting is nowadays widely recognized as a problem of great significance and social resonance, and still remains an open, grand challenge. Furthermore, the development of mobile warning systems and…

Quantitative Methods · Quantitative Biology 2018-12-10 Roberto Zingone , Chiara Mocenni , Dario Madeo

Electroencephalography (EEG) is a cornerstone of brain-computer interfaces and clinical neuroscience, yet deep learning models are typically trained and evaluated under a single, unreported preprocessing pipeline. We formalize preprocessing…

Machine Learning · Computer Science 2026-05-11 Dengzhe Hou , Zihao Wu , Lingyu Jiang , Zirui Li , Fangzhou Lin , Kazunori D. Yamada

Epilepsy affects more than 50 million people worldwide, making it one of the world's most prevalent neurological diseases. The main symptom of epilepsy is seizures, which occur abruptly and can cause serious injury or death. The ability to…

Signal Processing · Electrical Eng. & Systems 2024-02-06 Zakary Georgis-Yap , Milos R. Popovic , Shehroz S. Khan

The association between preoperative cognitive status and surgical outcomes is a critical, yet scarcely explored area of research. Linking intraoperative data with postoperative outcomes is a promising and low-cost way of evaluating…

Electroencephalography (EEG) is a neuroimaging technique that records brain neural activity with high temporal resolution. Unlike other methods, EEG does not require prohibitively expensive equipment and can be easily set up using…

Human-Computer Interaction · Computer Science 2024-10-01 Arash Akbarinia

Identifying causal relationships among distinct brain areas, known as effective connectivity, holds key insights into the brain's information processing and cognitive functions. Electroencephalogram (EEG) signals exhibit intricate dynamics…

Signal Processing · Electrical Eng. & Systems 2023-07-20 Peizhen Yang , Xinke Shen , Zongsheng Li , Zixiang Luo , Kexin Lou , Quanying Liu

We investigate the nature of the modifications in the temporal dynamics manifested in the high-frequency EEG spectra of the normal human brain in comparison to the diseased brain undergoing epilepsy. For this purpose, the Fourier…

Chaotic Dynamics · Physics 2025-08-19 Jyotiraj Nath , Shreya Banerjee , Bhaswati Singha Deo , Mayukha Pal , Prasanta K. Panigrahi

In this study, we developed and tested machine learning models to predict epilepsy surgical outcome using noninvasive clinical and demographic data from patients. Methods: Seven dif-ferent categorization algorithms were used to analyze the…

Seizure prediction has attracted a growing attention as one of the most challenging predictive data analysis efforts in order to improve the life of patients living with drug-resistant epilepsy and tonic seizures. Many outstanding works…

Computer Vision and Pattern Recognition · Computer Science 2017-12-07 Nhan Duy Truong , Anh Duy Nguyen , Levin Kuhlmann , Mohammad Reza Bonyadi , Jiawei Yang , Omid Kavehei

Insomnia affects a vast population of the world and can have a wide range of causes. Existing treatments for insomnia have been linked with many side effects like headaches, dizziness, etc. As such, there is a clear need for improved…

Signal Processing · Electrical Eng. & Systems 2025-07-22 Kevin Monteiro , Sam Nallaperuma-Herzberg , Martina Mason , Steve Niederer

Implantable, closed-loop devices for automated early detection and stimulation of epileptic seizures are promising treatment options for patients with severe epilepsy that cannot be treated with traditional means. Most approaches for early…

Epileptic seizures are generated in cerebral networks that propagate ictal and interictal activity. The structure of cerebral networks underpinning epileptic activity can be inferred from diffusion-weighted MRI (DWI). However, publicly…

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