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Epilepsy is one of the most serious neurological diseases, affecting 1-2% of the world's population. The diagnosis of epilepsy depends heavily on the recognition of epileptic waves, i.e., disordered electrical brainwave activity in the…

Signal Processing · Electrical Eng. & Systems 2023-06-26 Junru Chen , Yang Yang , Tao Yu , Yingying Fan , Xiaolong Mo , Carl Yang

Epilepsy is a neurological condition such that it affects the brain and the nervous system. It is characterized by recurrent seizures, which are physical reactions to sudden, usually brief, excessive electrical discharges in a group of…

Signal Processing · Electrical Eng. & Systems 2018-07-30 Asmaa Hamad , Aboul Ella Hassanien , Aly A. Fahmy , Essam H. Houssein

Complex network analysis has an increasing relevance in the study of neurological disorders, enhancing the knowledge of brain's structural and functional organization. Network structure and efficiency reveal different brain states along…

Neurons and Cognition · Quantitative Biology 2022-01-24 Nicolás J. Gallego-Molina , Andrés Ortiz , Francisco J. Martínez-Murcia , Marco Formoso , Almudena Giménez

Empirical studies over the past two decades have supported the hypothesis that schizophrenia is characterized by altered connectivity patterns in functional brain networks. These alterations have been proposed as genetically-mediated…

Neurons and Cognition · Quantitative Biology 2013-06-28 Felix Siebenhuhner , Shennan A. Weiss , Richard Coppola , Daniel R. Weinberger , Danielle S. Bassett

We investigate the suitability of selected measures of complexity based on recurrence quantification analysis and recurrence networks for an identification of pre-seizure states in multi-day, multi-channel, invasive electroencephalographic…

Many recent efforts in computational modeling of macro-scale brain dynamics have begun to take a data-driven approach by incorporating structural and/or functional information derived from subject data. Here, we discuss recent work using…

Neurons and Cognition · Quantitative Biology 2018-11-15 Kanika Bansal , Johan Nakuci , Sarah Feldt Muldoon

Epileptic seizures are considered as abnormally hypersynchronous neuronal activities of the brain. Do hypersynchronous neuronal activities in a brain region lead to seizure or the hypersynchronous activities take place due to the…

Neurons and Cognition · Quantitative Biology 2013-01-08 Kaushik Majumdar , Pradeep D. Prasad , Shailesh Verma

Background: Direct electrical stimulation of the brain through intracranial electrodes is currently used to probe the epileptic brain as part of pre-surgical evaluation, and it is also being considered for therapeutic treatments through…

Neurons and Cognition · Quantitative Biology 2020-11-18 Christoforos A Papasavvas , Gabrielle M Schroeder , Beate Diehl , Gerold Baier , Peter N Taylor , Yujiang Wang

Epilepsy is one of the most common and yet diverse set of chronic neurological disorders. This excessive or synchronous neuronal activity is termed seizure. Electroencephalogram signal processing plays a significant role in detection and…

Signal Processing · Electrical Eng. & Systems 2021-09-29 Paul Grant , Md Zahidul Islam

Epilepsy is a common neurological disorder characterized by recurrent seizures accompanied by excessive synchronous brain activity. The process of structural and functional brain alterations leading to increased seizure susceptibility and…

Signal Processing · Electrical Eng. & Systems 2020-06-18 Diyuan Lu , Sebastian Bauer , Valentin Neubert , Lara Sophie Costard , Felix Rosenow , Jochen Triesch

Objective: To identify if whole-brain structural network alterations in patients with temporal lobe epilepsy (TLE) and focal to bilateral tonic-clonic seizures (FBTCS) differ from alterations in patients without FBTCS. Methods: We…

The distributed nature of the neural substrate, and the difficulty of establishing necessity from correlative data, combine to render the mapping of brain function a far harder task than it seems. Methods capable of combining connective…

A brain wide association study (BWAS) based on the logistic regression was first developed and applied to a large population of epilepsy patients (168) and healthy controls (136). It was found that the most significant links associated with…

Medical Physics · Physics 2012-09-26 Wei Cheng , Xuejuan Zhang , Ge Tian , Jianfeng Feng , Zhengge Wang , Zhiqiang Zhang , GuangMing Lu

Epilepsy is one of the most occurring neurological disease globally emerged back in 4000 BC. It is affecting around 50 million people of all ages these days. The trait of this disease is recurrent seizures. In the past few decades, the…

Machine Learning · Computer Science 2021-11-08 Virender Ranga , Shivam Gupta , Jyoti Meena , Priyansh Agrawal

The evidence indicates that intracranial EEG connectivity, as estimated from daily resting state recordings from epileptic patients, may be capable of identifying preictal states. In this study, we employed hyperbolic embedding of brain…

Neurons and Cognition · Quantitative Biology 2025-05-28 Martin Guillemaud , Louis Cousyn , Vincent Navarro , Mario Chavez

Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…

Neurons and Cognition · Quantitative Biology 2019-08-12 Teresa M. Karrer , Jason Z. Kim , Jennifer Stiso , Ari E. Kahn , Fabio Pasqualetti , Ute Habel , Danielle S. Bassett

Over one third of the estimated 3 million people with epilepsy in the US are medication resistant. Responsive neurostimulation from chronically implanted electrodes provides a promising treatment option and alternative to resective surgery.…

Complex spatial connectivity patterns, such as interictal suppression and ictal propagation, complicate accurate drug-resistant epilepsy (DRE) seizure detection using stereotactic electroencephalography (SEEG) and traditional machine…

Signal Processing · Electrical Eng. & Systems 2025-12-03 Yiping Wang , Peiren Wang , Zhenye Li , Fang Liu , Jinguo Huang

Epilepsy significantly impacts global health, affecting about 65 million people worldwide, along with various animal species. The diagnostic processes of epilepsy are often hindered by the transient and unpredictable nature of seizures.…

Signal Processing · Electrical Eng. & Systems 2026-04-21 Z. Wang , S. Li , Dongrui Wu

The analysis of electrophysiological signal of scalp: EEG (electroencephalography), MEG (magnetoencephalography) and depth (intracerebral EEG) IEEG is a way to delimit epileptogenic zone (EZ). These epileptic signals present two different…

Signal Processing · Electrical Eng. & Systems 2019-11-19 Amira Hajjeji , Nawel Jmail , Abir Hadriche , Amal Ncibi , Chokri Ben Amar
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