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Wav2vec-C introduces a novel representation learning technique combining elements from wav2vec 2.0 and VQ-VAE. Our model learns to reproduce quantized representations from partially masked speech encoding using a contrastive loss in a way…

Audio and Speech Processing · Electrical Eng. & Systems 2021-06-25 Samik Sadhu , Di He , Che-Wei Huang , Sri Harish Mallidi , Minhua Wu , Ariya Rastrow , Andreas Stolcke , Jasha Droppo , Roland Maas

After the completion of human genome sequence was anounced, it is evident that interpretation of DNA sequences is an immediate task to work on. For understanding their signals, improvement of present sequence analysis tools and developing…

Computational Complexity · Computer Science 2007-05-23 Gene Kim , MyungHo Kim

Recent advances of information technology in biomedical sciences and other applied areas have created numerous large diverse data sets with a high dimensional feature space, which provide us a tremendous amount of information and new…

Applications · Statistics 2008-12-18 Yulan Liang , Arpad Kelemen

We present a framework for learning cross-modal video representations by directly pre-training on raw data to facilitate various downstream video-text tasks. Our main contributions lie in the pre-training framework and proxy tasks. First,…

Computer Vision and Pattern Recognition · Computer Science 2024-02-01 Xingning Dong , Qingpei Guo , Tian Gan , Qing Wang , Jianlong Wu , Xiangyuan Ren , Yuan Cheng , Wei Chu

We propose self-adaptive training -- a unified training algorithm that dynamically calibrates and enhances training processes by model predictions without incurring an extra computational cost -- to advance both supervised and…

Machine Learning · Computer Science 2022-10-17 Lang Huang , Chao Zhang , Hongyang Zhang

Background: Advances in high throughput sequencing technologies provide a huge number of genomes to be analyzed. Thus, computational methods play a crucial role in analyzing and extracting knowledge from the data generated. Investigating…

Genome-wide association studies (GWA studies or GWAS) investigate the relationships between genetic variants such as single-nucleotide polymorphisms (SNPs) and individual traits. Recently, incorporating biological priors together with…

Machine Learning · Statistics 2017-09-13 Tao Yang , Paul Thompson , Sihai Zhao , Jieping Ye

Selecting the most appropriate data examples to present a deep neural network (DNN) at different stages of training is an unsolved challenge. Though practitioners typically ignore this problem, a non-trivial data scheduling method may…

Machine Learning · Computer Science 2018-07-25 Vithursan Thangarasa , Graham W. Taylor

With the progress of sensor technology in wearables, the collection and analysis of PPG signals are gaining more interest. Using Machine Learning, the cardiac rhythm corresponding to PPG signals can be used to predict different tasks such…

Signal Processing · Electrical Eng. & Systems 2022-12-20 Ramin Ghorbani , Marcel J. T. Reinders , David M. J. Tax

Genome-wide association studies (GWASs) aim to detect genetic risk factors for complex human diseases by identifying disease-associated single-nucleotide polymorphisms (SNPs). The traditional SNP-wise approach along with multiple testing…

Methodology · Statistics 2019-09-25 Yan Xu , Li Xing , Jessica Su , Xuekui Zhang , Weiliang Qiu

The supervised learning paradigm is limited by the cost - and sometimes the impracticality - of data collection and labeling in multiple domains. Self-supervised learning, a paradigm which exploits the structure of unlabeled data to create…

This paper proposes a novel self-supervised learning method for semantic segmentation using selective masking image reconstruction as the pretraining task. Our proposed method replaces the random masking augmentation used in most masked…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Yuemin Wang , Ian Stavness

Sensory input from multiple sources is crucial for robust and coherent human perception. Different sources contribute complementary explanatory factors. Similarly, research studies often collect multimodal imaging data, each of which can…

Predicting protein secondary structure is a fundamental problem in protein structure prediction. Here we present a new supervised generative stochastic network (GSN) based method to predict local secondary structure with deep hierarchical…

Quantitative Methods · Quantitative Biology 2014-03-07 Jian Zhou , Olga G. Troyanskaya

Cell type identification from single-cell transcriptomic data is a common goal of single-cell RNA sequencing (scRNAseq) data analysis. Neural networks have been employed to identify cell types from scRNAseq data with high performance.…

Genomics · Quantitative Biology 2020-05-11 Xishuang Dong , Shanta Chowdhury , Uboho Victor , Xiangfang Li , Lijun Qian

We present a method for transferring pre-trained self-supervised (SSL) speech representations to multiple languages. There is an abundance of unannotated speech, so creating self-supervised representations from raw audio and fine-tuning on…

Audio and Speech Processing · Electrical Eng. & Systems 2022-02-08 Samuel Kessler , Bethan Thomas , Salah Karout

Protein representation learning methods have shown great potential to yield useful representation for many downstream tasks, especially on protein classification. Moreover, a few recent studies have shown great promise in addressing…

Machine Learning · Computer Science 2023-04-11 Can Chen , Jingbo Zhou , Fan Wang , Xue Liu , Dejing Dou

Recently proposed self-supervised learning approaches have been successful for pre-training speech representation models. The utility of these learned representations has been observed empirically, but not much has been studied about the…

Computation and Language · Computer Science 2022-12-06 Ankita Pasad , Ju-Chieh Chou , Karen Livescu

Unsupervised pre-training and transfer learning are commonly used techniques to initialize training algorithms for neural networks, particularly in settings with limited labeled data. In this paper, we study the effects of unsupervised…

Machine Learning · Statistics 2025-06-12 Taj Jones-McCormick , Aukosh Jagannath , Subhabrata Sen

Given genetic variations and various phenotypical traits, such as Magnetic Resonance Imaging (MRI) features, we consider two important and related tasks in biomedical research: i)to select genetic and phenotypical markers for disease…

Machine Learning · Computer Science 2013-10-17 Shandian Zhe , Zenglin Xu , Yuan Qi