English
Related papers

Related papers: SNP2Vec: Scalable Self-Supervised Pre-Training for…

200 papers

We argue that time series analysis is fundamentally different in nature to either vision or natural language processing with respect to the forms of meaningful self-supervised learning tasks that can be defined. Motivated by this insight,…

Machine Learning · Computer Science 2023-12-13 Navid Mohammadi Foumani , Chang Wei Tan , Geoffrey I. Webb , Hamid Rezatofighi , Mahsa Salehi

Self-supervised learning (SSL) plays a central role in molecular representation learning. Yet, many recent innovations in masking-based pretraining are introduced as heuristics and lack principled evaluation, obscuring which design choices…

Machine Learning · Computer Science 2025-12-09 Jiannan Yang , Veronika Thost , Tengfei Ma

Representation learning methods that transform encoded data (e.g., diagnosis and drug codes) into continuous vector spaces (i.e., vector embeddings) are critical for the application of deep learning in healthcare. Initial work in this area…

Machine Learning · Computer Science 2019-07-23 Khushbu Agarwal , Tome Eftimov , Raghavendra Addanki , Sutanay Choudhury , Suzanne Tamang , Robert Rallo

Self-supervised pretraining attempts to enhance model performance by obtaining effective features from unlabeled data, and has demonstrated its effectiveness in the field of histopathology images. Despite its success, few works concentrate…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Zhiyun Song , Penghui Du , Junpeng Yan , Kailu Li , Jianzhong Shou , Maode Lai , Yubo Fan , Yan Xu

In the genome biology research, regulatory genome modeling is an important topic for many regulatory downstream tasks, such as promoter classification, transaction factor binding sites prediction. The core problem is to model how regulatory…

Genomics · Quantitative Biology 2021-11-04 Shentong Mo , Xi Fu , Chenyang Hong , Yizhen Chen , Yuxuan Zheng , Xiangru Tang , Zhiqiang Shen , Eric P Xing , Yanyan Lan

Language model based methods are powerful techniques for text classification. However, the models have several shortcomings. (1) It is difficult to integrate human knowledge such as keywords. (2) It needs a lot of resources to train the…

Computation and Language · Computer Science 2024-02-09 Weijie Xu , Jay Desai , Srinivasan Sengamedu , Xiaoyu Jiang , Francis Iannacci

Recently, machine learning-based semantic segmentation algorithms have demonstrated their potential to accurately segment regions and contours in medical images, allowing the precise location of anatomical structures and abnormalities.…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Yifei Wang , Chuhong Zhu

Alzheimer's disease is a progressive, neurodegenerative disorder that causes memory loss and cognitive decline. While there has been extensive research in applying deep learning models to Alzheimer's prediction tasks, these models remain…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Emily Kaczmarek , Justin Szeto , Brennan Nichyporuk , Tal Arbel

Genome Wide Association Studies (GWAS) are used to identify statistically significant genetic variants in case-control studies. GWAS typically use a p-value threshold of 5 x 10-8 to identify highly ranked single nucleotide polymorphisms…

Computational Engineering, Finance, and Science · Computer Science 2018-01-10 Paul Fergus , Casimiro Curbelo Montanez , Basma Abdulaimma , Paulo Lisboa , Carl Chalmers

Deep learning has shown significant potential in diagnosing neurodegenerative diseases from MRI data. However, most existing methods rely heavily on large volumes of labeled data and often yield representations that lack interpretability.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Fangqi Cheng , Yingying Zhao , Xiaochen Yang

In this paper, we investigate self-supervised pre-training methods for document text recognition. Nowadays, large unlabeled datasets can be collected for many research tasks, including text recognition, but it is costly to annotate them.…

Computer Vision and Pattern Recognition · Computer Science 2024-05-02 Martin Kišš , Michal Hradiš

Genome-wide association studies (GWAS) are commonly employed to study the genetic basis of complex traits and diseases, and a key question is how much heritability could be explained by all variants in GWAS. One widely used approach that…

Genomics · Quantitative Biology 2023-06-27 Hon-Cheong So , Xiao Xue , Pak-Chung Sham

Deep neural networks are typically trained under a supervised learning framework where a model learns a single task using labeled data. Instead of relying solely on labeled data, practitioners can harness unlabeled or related data to…

Machine Learning · Computer Science 2020-07-03 Huanru Henry Mao

Support Vector Machines (SVM), a popular machine learning technique, has been applied to a wide range of domains such as science, finance, and social networks for supervised learning. Whether it is identifying high-risk patients by…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-06-20 Jeyanthi Narasimhan , Abhinav Vishnu , Lawrence Holder , Adolfy Hoisie

The analysis of physiological processes over time are often given by spectrometric or gene expression profiles over time with only few time points but a large number of measured variables. The analysis of such temporal sequences is…

Machine Learning · Computer Science 2011-10-12 F. -M. Schleif , A. Gisbrecht , B. Hammer

We consider applying Bayesian Variable Selection Regression, or BVSR, to genome-wide association studies and similar large-scale regression problems. Currently, typical genome-wide association studies measure hundreds of thousands, or…

Applications · Statistics 2011-10-28 Yongtao Guan , Matthew Stephens

Labeling of multivariate biomedical time series data is a laborious and expensive process. Self-supervised contrastive learning alleviates the need for large, labeled datasets through pretraining on unlabeled data. However, for multivariate…

Machine Learning · Statistics 2023-07-21 Thea Brüsch , Mikkel N. Schmidt , Tommy S. Alstrøm

Recent neuroimaging studies that focus on predicting brain disorders via modern machine learning approaches commonly include a single modality and rely on supervised over-parameterized models.However, a single modality provides only a…

While the general idea of self-supervised learning is identical across modalities, the actual algorithms and objectives differ widely because they were developed with a single modality in mind. To get us closer to general self-supervised…

Machine Learning · Computer Science 2022-10-27 Alexei Baevski , Wei-Ning Hsu , Qiantong Xu , Arun Babu , Jiatao Gu , Michael Auli

In text recognition, self-supervised pre-training emerges as a good solution to reduce dependence on expansive annotated real data. Previous studies primarily focus on local visual representation by leveraging mask image modeling or…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Zuan Gao , Yuxin Wang , Yadong Qu , Boqiang Zhang , Zixiao Wang , Jianjun Xu , Hongtao Xie