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This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Background: Widespread adoption of electronic health records (EHRs) has enabled secondary use of EHR data for clinical research and healthcare delivery. Natural language processing (NLP) techniques have shown promise in their capability to…

Information Retrieval · Computer Science 2021-06-15 Sijia Liu , Yanshan Wang , Andrew Wen , Liwei Wang , Na Hong , Feichen Shen , Steven Bedrick , William Hersh , Hongfang Liu

Despite impressive success of machine learning algorithms in clinical natural language processing (cNLP), rule-based approaches still have a prominent role. In this paper, we introduce medspaCy, an extensible, open-source cNLP library based…

Computation and Language · Computer Science 2021-06-16 Hannah Eyre , Alec B Chapman , Kelly S Peterson , Jianlin Shi , Patrick R Alba , Makoto M Jones , Tamara L Box , Scott L DuVall , Olga V Patterson

Electronic health records (EHRs) contain vast amounts of complex data, but harmonizing and processing this information remains a challenging and costly task requiring significant clinical expertise. While large language models (LLMs) have…

Computation and Language · Computer Science 2024-07-02 João Matos , Jack Gallifant , Jian Pei , A. Ian Wong

The lack of standardized evaluation benchmarks in the medical domain for text inputs can be a barrier to widely adopting and leveraging the potential of natural language models for health-related downstream tasks. This paper revisited an…

Computation and Language · Computer Science 2025-04-30 Jesus Lovon , Thouria Ben-Haddi , Jules Di Scala , Jose G. Moreno , Lynda Tamine

Clinical language models are important for many applications in healthcare, but their development depends on access to extensive clinical text for pretraining. However, obtaining clinical notes from electronic health records (EHRs) at scale…

Computation and Language · Computer Science 2024-12-02 Jinghui Liu , Anthony Nguyen

This article reviews recent advances in applying natural language processing (NLP) to Electronic Health Records (EHRs) for computational phenotyping. NLP-based computational phenotyping has numerous applications including diagnosis…

Computation and Language · Computer Science 2018-06-18 Zexian Zeng , Yu Deng , Xiaoyu Li , Tristan Naumann , Yuan Luo

Background: Clinical natural language processing (NLP) refers to the use of computational methods for extracting, processing, and analyzing unstructured clinical text data, and holds a huge potential to transform healthcare in various…

While text mining and NLP research has been established for decades, there remain gaps in the literature that reports the use of these techniques in building real-world applications. For example, they typically look at single and sometimes…

Computation and Language · Computer Science 2023-01-10 Ziqi Zhang , Tomas Jasaitis , Richard Freeman , Rowida Alfrjani , Adam Funk

The field of clinical natural language processing has been advanced significantly since the introduction of deep learning models. The self-supervised representation learning and the transfer learning paradigm became the methods of choice in…

Computation and Language · Computer Science 2020-04-27 Andrey Kormilitzin , Nemanja Vaci , Qiang Liu , Alejo Nevado-Holgado

Electronic Health Records (EHRs) contain rich yet complex information, and their automated analysis is critical for clinical decision-making. Despite recent advances of large language models (LLMs) in clinical workflows, their ability to…

Computation and Language · Computer Science 2025-11-26 Yusheng Liao , Chaoyi Wu , Junwei Liu , Shuyang Jiang , Pengcheng Qiu , Haowen Wang , Yun Yue , Shuai Zhen , Jian Wang , Qianrui Fan , Jinjie Gu , Ya Zhang , Yanfeng Wang , Yu Wang , Weidi Xie

Pretraining has proven to be a powerful technique in natural language processing (NLP), exhibiting remarkable success in various NLP downstream tasks. However, in the medical domain, existing pretrained models on electronic health records…

Artificial Intelligence · Computer Science 2023-10-23 Xiaochen Wang , Junyu Luo , Jiaqi Wang , Ziyi Yin , Suhan Cui , Yuan Zhong , Yaqing Wang , Fenglong Ma

Coding diagnosis and procedures in medical records is a crucial process in the healthcare industry, which includes the creation of accurate billings, receiving reimbursements from payers, and creating standardized patient care records. In…

Computation and Language · Computer Science 2020-01-01 Siddhartha Nuthakki , Sunil Neela , Judy W. Gichoya , Saptarshi Purkayastha

Electronic health record (EHR) is more and more popular, and it comes with applying machine learning solutions to resolve various problems in the domain. This growing research area also raises the need for EHRs accessibility. Medical…

Machine Learning · Computer Science 2024-01-30 Hung Bui , Harikrishna Warrier , Yogesh Gupta

Electronic health records (EHR) contain extensive structured and unstructured data, including tabular information and free-text clinical notes. Querying relevant patient information often requires complex database operations, increasing the…

Information Retrieval · Computer Science 2025-11-27 Mengliang ZHang

The extraction of critical patient information from Electronic Health Records (EHRs) poses significant challenges due to the complexity and unstructured nature of the data. Traditional machine learning approaches often fail to capture…

Computation and Language · Computer Science 2025-09-03 Zhimeng Luo , Abhibha Gupta , Adam Frisch , Daqing He

In studies that rely on data from electronic health records (EHRs), unstructured text data such as clinical progress notes offer a rich source of information about patient characteristics and care that may be missing from structured data.…

Computation and Language · Computer Science 2024-05-22 Reagan Mozer , Aaron R. Kaufman , Leo A. Celi , Luke Miratrix

Daily progress notes are common types in the electronic health record (EHR) where healthcare providers document the patient's daily progress and treatment plans. The EHR is designed to document all the care provided to patients, but it also…

Artificial Intelligence · Computer Science 2023-03-15 Yanjun Gao , Dmitriy Dligach , Timothy Miller , Matthew M Churpek , Ozlem Uzuner , Majid Afshar

Electronic Health Records (EHRs) provide crucial information for clinical decision-making. However, their high-dimensionality, heterogeneity, and sparsity make clinical prediction challenging. Large Language Models (LLMs) allowed progress…

Computation and Language · Computer Science 2026-01-28 Jesus Lovon-Melgarejo , Jose G. Moreno , Christine Damase-Michel , Lynda Tamine

Despite the growing availability of Electronic Health Record (EHR) data, researchers often face substantial barriers in effectively using these data for translational research due to their complexity, heterogeneity, and lack of standardized…