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Malware classification is a difficult problem, to which machine learning methods have been applied for decades. Yet progress has often been slow, in part due to a number of unique difficulties with the task that occur through all stages of…

Cryptography and Security · Computer Science 2020-11-17 Edward Raff , Charles Nicholas

Learning from noisy labels remains a major challenge in medical image analysis, where annotation demands expert knowledge and substantial inter-observer variability often leads to inconsistent or erroneous labels. Despite extensive research…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Yuan Ma , Junlin Hou , Chao Zhang , Yukun Zhou , Zongyuan Ge , Haoran Xie , Lie Ju

Motivation: Medical image analysis involves tasks to assist physicians in qualitative and quantitative analysis of lesions or anatomical structures, significantly improving the accuracy and reliability of diagnosis and prognosis.…

Computer Vision and Pattern Recognition · Computer Science 2022-06-30 Mingzhe Hu , Jiahan Zhang , Luke Matkovic , Tian Liu , Xiaofeng Yang

While the need for well-trained, fair ML systems is increasing ever more, measuring fairness for modern models and datasets is becoming increasingly difficult as they grow at an unprecedented pace. One key challenge in scaling common…

Artificial Intelligence · Computer Science 2022-01-19 Alex Bäuerle , Aybuke Gul Turker , Ken Burke , Osman Aka , Timo Ropinski , Christina Greer , Mani Varadarajan

The evaluation of supervised machine learning models is a critical stage in the development of reliable predictive systems. Despite the widespread availability of machine learning libraries and automated workflows, model assessment is often…

Machine Learning · Computer Science 2026-04-16 Xuanyan Liu , Ignacio Cabrera Martin , Marcello Trovati , Xiaolong Xu , Nikolaos Polatidis

Increasing evidence shows that flaws in machine learning (ML) algorithm validation are an underestimated global problem. Particularly in automatic biomedical image analysis, chosen performance metrics often do not reflect the domain…

Machine-learning (ML) models in flow cytometry have the potential to reduce error rates, increase reproducibility, and boost the efficiency of clinical labs. While numerous ML models for flow cytometry data have been proposed, few studies…

This paper discusses some overlooked challenges faced when working with machine learning models for histopathology and presents a novel opportunity to support "Learning Health Systems" with them. Initially, the authors elaborate on these…

Computer Vision and Pattern Recognition · Computer Science 2023-12-08 Ricardo Gonzalez , Ashirbani Saha , Clinton J. V. Campbell , Peyman Nejat , Cynthia Lokker , Andrew P. Norgan

Manual segmentation of medical images (e.g., segmenting tumors in CT scans) is a high-effort task that can be accelerated with machine learning techniques. However, selecting the right segmentation approach depends on the evaluation…

Computer Vision and Pattern Recognition · Computer Science 2023-02-09 Seyed M. R. Modaresi , Aomar Osmani , Mohammadreza Razzazi , Abdelghani Chibani

As cyber attacks continue to increase in frequency and sophistication, detecting malware has become a critical task for maintaining the security of computer systems. Traditional signature-based methods of malware detection have limitations…

Cryptography and Security · Computer Science 2024-03-05 Khatoon Mohammed

Microelectronic design verification remains a critical bottleneck in device development, traditionally mitigated by expanding verification teams and computational resources. Since the late 1990s, machine learning (ML) has been proposed to…

Hardware Architecture · Computer Science 2025-03-18 Christopher Bennett , Kerstin Eder

Malware is being increasingly threatening and malware detectors based on traditional signature-based analysis are no longer suitable for current malware detection. Recently, the models based on machine learning (ML) are developed for…

Cryptography and Security · Computer Science 2021-01-18 Yuzhou Lin , Xiaolin Chang

Background: The rapid advancement of Machine Learning (ML) represents novel opportunities to enhance public health research, surveillance, and decision-making. However, there is a lack of comprehensive understanding of algorithmic bias,…

Machine Learning · Computer Science 2024-09-04 Shaina Raza , Arash Shaban-Nejad , Elham Dolatabadi , Hiroshi Mamiya

As machine learning (ML) systems increasingly permeate high-stakes settings such as healthcare, transportation, military, and national security, concerns regarding their reliability have emerged. Despite notable progress, the performance of…

Machine Learning · Computer Science 2023-08-01 Anthony Corso , David Karamadian , Romeo Valentin , Mary Cooper , Mykel J. Kochenderfer

To learn about real world phenomena, scientists have traditionally used models with clearly interpretable elements. However, modern machine learning (ML) models, while powerful predictors, lack this direct elementwise interpretability (e.g.…

Machine Learning · Statistics 2024-07-16 Timo Freiesleben , Gunnar König , Christoph Molnar , Alvaro Tejero-Cantero

The rapid global aging trend has led to an increase in dementia cases, including Alzheimer's disease, underscoring the urgent need for early and accurate diagnostic methods. Traditional diagnostic techniques, such as cognitive tests,…

Machine Learning · Computer Science 2024-09-06 Juan A. Berrios Moya

Many domains now leverage the benefits of Machine Learning (ML), which promises solutions that can autonomously learn to solve complex tasks by training over some data. Unfortunately, in cyberthreat detection, high-quality data is hard to…

Cryptography and Security · Computer Science 2023-12-12 Tobias Braun , Irdin Pekaric , Giovanni Apruzzese

Medical image diagnosis is challenging because many diseases resemble normal anatomy and exhibit substantial interpatient variability. Clinicians routinely rely on comparative diagnosis, such as referencing cross-patient healthy control…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Ruinan Jin , Gexin Huang , Xinwei Shen , Qiong Zhang , Yan Shuo Tan , Xiaoxiao Li

Music Recommender Systems (MRS) have long relied on an information-retrieval framing, where progress is measured mainly through accuracy on retrieval-oriented subtasks. While effective, this reductionist paradigm struggles to address the…

Information Retrieval · Computer Science 2025-11-21 Elena V. Epure , Yashar Deldjoo , Bruno Sguerra , Markus Schedl , Manuel Moussallam

The integration of machine learning in medical image analysis can greatly enhance the quality of healthcare provided by physicians. The combination of human expertise and computerized systems can result in improved diagnostic accuracy. An…

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