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Despite their successes in vision and language, foundation models have stumbled in pathology, revealing low accuracy, instability, and heavy computational demands. These shortcomings stem not from tuning problems but from deeper conceptual…

Artificial Intelligence · Computer Science 2026-04-21 Hamid R. Tizhoosh

Medical image classification involves thresholding of labels that represent malignancy risk levels. Usually, a task defines a single threshold, and when developing computer-aided diagnosis tools, a single network is trained per such…

Computer Vision and Pattern Recognition · Computer Science 2018-11-22 Vadim Ratner , Yoel Shoshan , Tal Kachman

Computational pathology can lead to saving human lives, but models are annotation hungry and pathology images are notoriously expensive to annotate. Self-supervised learning has shown to be an effective method for utilizing unlabeled data,…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Mingu Kang , Heon Song , Seonwook Park , Donggeun Yoo , Sérgio Pereira

Machine learning (ML) models are only as good as the data they are trained on. But recent studies have found datasets widely used to train and evaluate ML models, e.g. ImageNet, to have pervasive labeling errors. Erroneous labels on the…

Machine Learning · Computer Science 2024-01-17 Mononito Goswami , Vedant Sanil , Arjun Choudhry , Arvind Srinivasan , Chalisa Udompanyawit , Artur Dubrawski

Commonly, AI or machine learning (ML) models are evaluated on benchmark datasets. This practice supports innovative methodological research, but benchmark performance can be poorly correlated with performance in real-world applications -- a…

Machine Learning · Computer Science 2024-06-18 Olivier Binette , Jerome P. Reiter

Machine learning (ML) is poised to drive innovations in clinical microbiomics, such as in disease diagnostics and prognostics. However, the successful implementation of ML in these domains necessitates the development of reproducible,…

Genomics · Quantitative Biology 2024-12-02 Natasha K. Dudek , Mariam Chakhvadze , Saba Kobakhidze , Omar Kantidze , Yuriy Gankin

Large language models (LLMs) hold promise for transforming healthcare, from streamlining administrative and clinical workflows to enriching patient engagement and advancing clinical decision-making. However, their successful integration…

Computers and Society · Computer Science 2025-04-04 Mohammed Al-Garadi , Tushar Mungle , Abdulaziz Ahmed , Abeed Sarker , Zhuqi Miao , Michael E. Matheny

Medical image classification is a critical problem for healthcare, with the potential to alleviate the workload of doctors and facilitate diagnoses of patients. However, two challenges arise when deploying deep learning models to real-world…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 An Yan , Yu Wang , Yiwu Zhong , Zexue He , Petros Karypis , Zihan Wang , Chengyu Dong , Amilcare Gentili , Chun-Nan Hsu , Jingbo Shang , Julian McAuley

Although deep learning (DL) models have shown great success in many medical image analysis tasks, deployment of the resulting models into real clinical contexts requires: (1) that they exhibit robustness and fairness across different…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Raghav Mehta , Changjian Shui , Tal Arbel

The use of machine learning (ML) techniques in the biomedical field has become increasingly important, particularly with the large amounts of data generated by the aftermath of the COVID-19 pandemic. However, due to the complex nature of…

Machine Learning · Computer Science 2023-03-17 Anthony Onoja , Francesco Raimondi

Machine learning (ML) has become a critical tool in public health, offering the potential to improve population health, diagnosis, treatment selection, and health system efficiency. However, biases in data and model design can result in…

Machine Learning · Computer Science 2023-04-12 Shaina Raza

Machine learning (ML) models show strong promise for new biomedical prediction tasks, but concerns about trustworthiness have hindered their clinical adoption. In particular, it is often unclear whether a model relies on true clinical cues…

Machine Learning · Computer Science 2026-01-13 Dushan N. Wadduwage , Dineth Jayakody , Leonidas Zimianitis

In a world where Machine Learning (ML) is increasingly deployed to support decision-making in critical domains, providing decision-makers with explainable, stable, and relevant inputs becomes fundamental. Understanding how machine learning…

Machine Learning · Computer Science 2024-08-07 Karol Capała , Paulina Tworek , Jose Sousa

Objective: The growing availability of large-scale observational clinical datasets and challenges in conducting randomized controlled trials have spurred enthusiasm in using causal machine learning (ML) for causal inference in observational…

Domain gaps are among the most relevant roadblocks in the clinical translation of machine learning (ML)-based solutions for medical image analysis. While current research focuses on new training paradigms and network architectures, little…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Patrick Godau , Piotr Kalinowski , Evangelia Christodoulou , Annika Reinke , Minu Tizabi , Luciana Ferrer , Paul Jäger , Lena Maier-Hein

Machine Learning is a diverse field applied across various domains such as computer science, social sciences, medicine, chemistry, and finance. This diversity results in varied evaluation approaches, making it difficult to compare models…

Machine Learning · Computer Science 2025-07-08 Silvia Beddar-Wiesing , Alice Moallemy-Oureh , Marie Kempkes , Josephine M. Thomas

The application of machine learning to radiological images is an increasingly active research area that is expected to grow in the next five to ten years. Recent advances in machine learning have the potential to recognize and classify…

Image and Video Processing · Electrical Eng. & Systems 2019-04-01 Zhenwei Zhang , Ervin Sejdic

The uptake of machine learning (ML) approaches in the social and health sciences has been rather slow, and research using ML for social and health research questions remains fragmented. This may be due to the separate development of…

Interpretation and diagnosis of machine learning models have gained renewed interest in recent years with breakthroughs in new approaches. We present Manifold, a framework that utilizes visual analysis techniques to support interpretation,…

Machine Learning · Computer Science 2019-01-18 Jiawei Zhang , Yang Wang , Piero Molino , Lezhi Li , David S. Ebert

Machine learning (ML) methods are having a huge impact across all of the sciences. However, ML has a strong ontology - in which only the data exist - and a strong epistemology - in which a model is considered good if it performs well on…

Machine Learning · Statistics 2024-06-04 David W. Hogg , Soledad Villar