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We address the optimal design of a large scale multi-agent system where each agent has discrete and/or continuous decision variables that need to be set so as to optimize the sum of linear local cost functions, in presence of linear local…

Optimization and Control · Mathematics 2017-06-28 Alessandro Falsone , Kostas Margellos , Maria Prandini

A mixed-integer linear programming (MILP) formulation is presented for parameter estimation of the Potts model. Two algorithms are developed; the first method estimates the parameters such that the set of ground states replicate the…

Data Structures and Algorithms · Computer Science 2021-02-03 Siddhartha Srivastava , Veera Sundararaghavan

Formulation symmetry in mixed-integer programming (MIP) can hinder solver performance by inducing redundant search, but detecting such symmetries is also a significant computational challenge. This paper explores the potential for quantum…

Optimization and Control · Mathematics 2025-12-18 Alexander While , Chen Chen

In this paper, we mainly study one class of convex mixed-integer nonlinear programming problems (MINLPs) with non-differentiable data. By dropping the differentiability assumption, we substitute gradients with subgradients obtained from KKT…

Optimization and Control · Mathematics 2015-09-22 Zhou Wei , M. Montaz Ali

ReLU neural networks have been modelled as constraints in mixed integer linear programming (MILP), enabling surrogate-based optimisation in various domains and efficient solution of machine learning certification problems. However, previous…

Optimization and Control · Mathematics 2023-12-05 Tom McDonald , Calvin Tsay , Artur M. Schweidtmann , Neil Yorke-Smith

Quantum computing provides a powerful framework for tackling computational problems that are classically intractable. The goal of this paper is to explore the use of quantum computers for solving relevant problems in systems and control…

Systems and Control · Electrical Eng. & Systems 2025-12-23 Jan Schneider , Julian Berberich

Mixed-Integer Linear Programming (MILP) is a fundamental and powerful framework for modeling complex optimization problems across diverse domains. Recently, learning-based methods have shown great promise in accelerating MILP solvers by…

Machine Learning · Computer Science 2025-11-05 Tianle Pu , Zijie Geng , Haoyang Liu , Shixuan Liu , Jie Wang , Li Zeng , Chao Chen , Changjun Fan

Machine Learning (ML) has been widely applied across numerous domains due to its ability to automatically identify informative patterns from data for various tasks. The availability of large-scale data and advanced computational power…

This study addresses the minor-embedding problem, which involves mapping the variables of an Ising model onto a quantum annealing processor. The primary motivation stems from the observed performance disparity of quantum annealers when…

Quantum Physics · Physics 2026-03-18 Aitor Gomez-Tejedor , Eneko Osaba , Esther Villar-Rodriguez

Test optimization contains test case selection and minimization, which is an important challenge in software testing and has been addressed with search-based approaches intensively in the past. Inspired by the recent advancement of using…

Software Engineering · Computer Science 2026-04-14 Yige Yang , Man Zhang , Tao Yue

Recent work has shown potential in using Mixed Integer Programming (MIP) solvers to optimize certain aspects of neural networks (NNs). However the intriguing approach of training NNs with MIP solvers is under-explored.…

Machine Learning · Computer Science 2023-04-03 Tómas Thorbjarnarson , Neil Yorke-Smith

Mixed Integer Linear Programming (MILP) is a fundamental class of NP-hard problems that has garnered significant attention from both academia and industry. The Branch-and-Bound (B\&B) method is the dominant approach for solving MILPs and…

Machine Learning · Computer Science 2025-11-27 Tongkai Lu , Shuai Ma , Chongyang Tao

Distributed quantum computing (DQC) has emerged as a promising approach to overcome the scalability limitations of monolithic quantum processors in terms of computational capability. However, realising the full potential of DQC requires…

Recent advancements in quantum annealing hardware and numerous studies in this area suggests that quantum annealers have the potential to be effective in solving unconstrained binary quadratic programming problems. Naturally, one may desire…

Quantum Physics · Physics 2019-03-01 Sahar Karimi , Pooya Ronagh

In this paper, we propose novel mixed-integer linear programming (MIP) formulations to model decision problems posed as influence diagrams. We also present a novel heuristic that can be employed to warm start the MIP solver, as well as…

Optimization and Control · Mathematics 2026-01-21 Helmi Hankimaa , Olli Herrala , Fabricio Oliveira , Jaan Tollander de Balsch

Machine learning interatomic potentials (MLIPs) enable atomistic simulations with near ab initio accuracy at significantly reduced computational cost, but their broader adoption is often limited by fragmented tooling, limited scalability,…

Indefinite quadratic programs (QPs) are known to be very difficult to be solved to global optimality, so are linear programs with linear complementarity constraints. Treating the former as a subclass of the latter, this paper presents a…

Optimization and Control · Mathematics 2025-03-18 Xinyao Zhang , Shaoning Han , Jong-Shi Pang

A novel framework has recently been proposed for designing the molecular structure of chemical compounds with a desired chemical property, where design of novel drugs is an important topic in bioinformatics and chemo-informatics. The…

Noisy intermediate-scale quantum (NISQ) devices are spearheading the second quantum revolution. Of these, quantum annealers are the only ones currently offering real world, commercial applications on as many as 5000 qubits. The size of…

A major limitation of current generations of quantum annealers is the sparse connectivity of manufactured qubits in the hardware graph. This technological limitation generated considerable interest, motivating efforts to design efficient…