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Recent years have seen significant advances in quantum/quantum-inspired technologies capable of approximately searching for the ground state of Ising spin Hamiltonians. The promise of leveraging such technologies to accelerate the solution…

Optimization and Control · Mathematics 2024-01-24 Robin Brown , David E. Bernal Neira , Davide Venturelli , Marco Pavone

Integer programming (IP), as the name suggests is an integer-variable-based approach commonly used to formulate real-world optimization problems with constraints. Currently, quantum algorithms reformulate the IP into an unconstrained form…

Quantum Physics · Physics 2024-07-31 Kapil Goswami , Peter Schmelcher , Rick Mukherjee

We address the solution of Mixed Integer Linear Programming (MILP) models with strong relaxations that are derived from Dantzig-Wolfe decompositions and allow a pseudo-polynomial pricing algorithm. We exploit their network-flow…

Optimization and Control · Mathematics 2021-06-01 Vinícius L. de Lima , Manuel Iori , Flávio K. Miyazawa

Ising machines are hardware solvers which aim to find the absolute or approximate ground states of the Ising model. The Ising model is of fundamental computational interest because it is possible to formulate any problem in the complexity…

Quantum Physics · Physics 2022-04-04 Naeimeh Mohseni , Peter L. McMahon , Tim Byrnes

Quantum Machine Learning (QML) represents a promising frontier at the intersection of quantum computing and artificial intelligence, aiming to leverage quantum computational advantages to enhance data-driven tasks. This review explores the…

Machine Learning · Computer Science 2025-07-14 Samarth Kashyap , Rohit K Ramakrishnan , Kumari Jyoti , Apoorva D Patel

Deep brain stimulation (DBS) programming remains a complex and time-consuming process, requiring manual selection of stimulation parameters to achieve therapeutic effects while minimizing adverse side-effects. This study explores…

Systems and Control · Electrical Eng. & Systems 2025-02-12 Anna Franziska Frigge , Alexander Medvedev

Mixed-integer linear programming (MILP), a widely used modeling framework for combinatorial optimization, are central to many scientific and engineering applications, yet remains computationally challenging at scale. Recent advances in deep…

Artificial Intelligence · Computer Science 2026-01-09 Peixin Huang , Yaoxin Wu , Yining Ma , Cathy Wu , Wen Song , Wei Zhang

This work introduces a framework to address the computational complexity inherent in Mixed-Integer Programming (MIP) models by harnessing the potential of deep learning. By employing deep learning, we construct problem-specific heuristics…

Optimization and Control · Mathematics 2024-05-13 Niki Triantafyllou , Maria M. Papathanasiou

We present a new mixed-integer programming (MIP) approach for offline multiple change-point detection by casting the problem as a globally optimal piecewise linear (PWL) fitting problem. Our main contribution is a family of strengthened MIP…

Optimization and Control · Mathematics 2026-02-13 Apoorva Narula , Santanu S. Dey , Yao Xie

Missing data presents a critical challenge in real-world datasets, significantly degrading the performance of machine learning models. While Large Language Models (LLMs) have recently demonstrated remarkable capabilities in tabular data…

Machine Learning · Computer Science 2025-07-14 Hossein Jamali

Discrete black-box optimization problems are challenging for model-based optimization (MBO) algorithms, such as Bayesian optimization, due to the size of the search space and the need to satisfy combinatorial constraints. In particular,…

Optimization and Control · Mathematics 2022-06-15 Theodore Papalexopoulos , Christian Tjandraatmadja , Ross Anderson , Juan Pablo Vielma , David Belanger

Mixed Integer Programming (MIP) is one of the most widely used modeling techniques for combinatorial optimization problems. In many applications, a similar MIP model is solved on a regular basis, maintaining remarkable similarities in model…

Artificial Intelligence · Computer Science 2019-09-10 Jian-Ya Ding , Chao Zhang , Lei Shen , Shengyin Li , Bing Wang , Yinghui Xu , Le Song

We propose a quantum-classical hybrid method for solving large-scale mixed-integer quadratic problems (MIQP). Although extended Benders decomposition is effective for MIQP, its master problem which handles the integer and quadratic…

Quantum Physics · Physics 2026-02-19 Takuma Yoshihara , Masayuki Ohzeki

We propose a mixed-integer quadratic programming (QP) solver that is suitable for use in embedded applications, for example, hybrid model predictive control (MPC). The solver is based on the branch-and-bound method, and uses a recently…

Optimization and Control · Mathematics 2022-11-24 Daniel Arnström , Daniel Axehill

Attack trees (ATs) are an important tool in security analysis, and an important part of AT analysis is computing metrics. However, metric computation is NP-complete in general. In this paper, we showcase the use of mixed integer linear…

Cryptography and Security · Computer Science 2023-09-12 Milan Lopuhaä-Zwakenberg , Mariëlle Stoelinga

Integer programming (IP) is an NP-hard combinatorial optimization problem that is widely used to represent a diverse set of real-world problems spanning multiple fields, such as finance, engineering, logistics, and operations research. It…

Quantum Physics · Physics 2025-08-20 Kapil Goswami , Peter Schmelcher , Rick Mukherjee

Quantum annealers, coherent Ising machines and digital Ising machines for solving quantum-inspired optimization problems have been developing rapidly due to their near-term applications. The numerical solvers of the digital Ising machines…

Quantum Physics · Physics 2024-09-04 Langyu Li , Daoyi Dong , Yu Pan

The alternating-current unit commitment problem provides a realistic representation of power system operations, which is a nonconvex mixed-integer nonlinear programming problem and hence is computationally intractable. A common relaxation…

Optimization and Control · Mathematics 2026-04-07 Yongzheng Dai

This paper addresses the problem of tightening the mixed-integer linear programming (MILP) formulation for continuous piecewise linear (CPWL) approximations of data sets in arbitrary dimensions. The MILP formulation leverages the…

Optimization and Control · Mathematics 2026-01-08 Quentin Ploussard , Xiang Li , Matija Pavičević

Mixed integer nonlinear programs (MINLPs) are arguably among the hardest optimization problems, with a wide range of applications. MINLP solvers that are based on linear relaxations and spatial branching work similar as mixed integer…

Optimization and Control · Mathematics 2019-02-08 Jakob Witzig , Timo Berthold , Stefan Heinz
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