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Evaluation of artificial intelligence (AI) models for low-dose CT lung cancer screening is limited by heterogeneous datasets, annotation standards, and evaluation protocols, making performance difficult to compare and translate across…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Fakrul Islam Tushar , Avivah Wang , Lavsen Dahal , Ehsan Samei , Michael R. Harowicz , Jayashree Kalpathy-Cramer , Kyle J. Lafata , Tina D. Tailor , Cynthia Rudin , Joseph Y. Lo

Lung cancer is the leading cause of death among different types of cancers. Every year, the lives lost due to lung cancer exceed those lost to pancreatic, breast, and prostate cancer combined. The survival rate for lung cancer patients is…

Image and Video Processing · Electrical Eng. & Systems 2023-02-17 Saleh Abunajm , Nelly Elsayed , Zag ElSayed , Murat Ozer

Recently, intelligent analysis of lung nodules with the assistant of computer aided detection (CAD) techniques can improve the accuracy rate of lung cancer diagnosis. However, existing CAD systems and pulmonary datasets mainly focus on…

Image and Video Processing · Electrical Eng. & Systems 2024-06-27 Muwei Jian , Haoran Zhang , Mingju Shao , Hongyu Chen , Huihui Huang , Yanjie Zhong , Changlei Zhang , Bin Wang , Penghui Gao

Early detection and rapid intervention of lung cancer are crucial. Nonetheless, ensuring an accurate diagnosis is challenging, as physicians' ability to interpret chest X-rays varies significantly depending on their experience and degree of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Hyeonjin Choi , Jinse Kim , Dong-yeon Yoo , Ju-sung Sun , Jung-won Lee

Lung cancer has been one of the leading causes of cancer-related deaths worldwide for years. With the emergence of deep learning, computer-assisted diagnosis (CAD) models based on learning algorithms can accelerate the nodule screening…

Image and Video Processing · Electrical Eng. & Systems 2023-05-03 Xuan Zhao , Benjamin Hou

A combination of traditional image processing methods with advanced neural networks concretes a predictive and preventive healthcare paradigm. This study offers rapid, accurate, and non-invasive diagnostic solutions that can significantly…

Deep Learning (DL) holds enormous potential for improving medical imaging diagnostics, yet the lack of interpretability in most models hampers clinical trust and adoption. This paper presents an explainable deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Sai Teja Erukude , Viswa Chaitanya Marella , Suhasnadh Reddy Veluru

Risk stratification of lung nodules is a task of primary importance in lung cancer diagnosis. Any improvement in robust and accurate nodule characterization can assist in identifying cancer stage, prognosis, and improving treatment…

Computer Vision and Pattern Recognition · Computer Science 2017-10-27 Sarfaraz Hussein , Kunlin Cao , Qi Song , Ulas Bagci

The accurate diagnosis of pathological subtypes of lung cancer is of paramount importance for follow-up treatments and prognosis managements. Assessment methods utilizing deep learning technologies have introduced novel approaches for…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Yuan Jin , Gege Ma , Geng Chen , Tianling Lyu , Jan Egger , Junhui Lyu , Shaoting Zhang , Wentao Zhu

Objectives: To compare artificial intelligence (AI) as a second reader in detecting lung nodules on chest X-rays (CXR) versus radiologists of two binational institutions, and to evaluate AI performance when using two different modes:…

We present a deep learning framework for computer-aided lung cancer diagnosis. Our multi-stage framework detects nodules in 3D lung CAT scans, determines if each nodule is malignant, and finally assigns a cancer probability based on these…

Computer Vision and Pattern Recognition · Computer Science 2017-05-29 Kingsley Kuan , Mathieu Ravaut , Gaurav Manek , Huiling Chen , Jie Lin , Babar Nazir , Cen Chen , Tse Chiang Howe , Zeng Zeng , Vijay Chandrasekhar

Lung nodule malignancy prediction is an essential step in the early diagnosis of lung cancer. Besides the difficulties commonly discussed, the challenges of this task also come from the ambiguous labels provided by annotators, since deep…

Image and Video Processing · Electrical Eng. & Systems 2021-04-26 Zehui Liao , Yutong Xie , Shishuai Hu , Yong Xia

Recently, lung nodule detection methods based on deep learning have shown excellent performance in the medical image processing field. Considering that only a few public lung datasets are available and lung nodules are more difficult to…

Image and Video Processing · Electrical Eng. & Systems 2024-03-08 Yujiang Chen , Mei Xie

Accurate pulmonary nodule detection is a crucial step in lung cancer screening. Computer-aided detection (CAD) systems are not routinely used by radiologists for pulmonary nodule detection in clinical practice despite their potential…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Sunyi Zheng , Jiapan Guo , Xiaonan Cui , Raymond N. J. Veldhuis , Matthijs Oudkerk , Peter M. A. van Ooijen

We propose a deep learning based method for classification of commonly occurring pathologies in chest X-ray images. The vast number of publicly available chest X-ray images provides the data necessary for successfully employing deep…

Image and Video Processing · Electrical Eng. & Systems 2020-06-24 Mohammad S. Majdi , Khalil N. Salman , Michael F. Morris , Nirav C. Merchant , Jeffrey J. Rodriguez

We present a deep convolutional neural network for breast cancer screening exam classification, trained and evaluated on over 200,000 exams (over 1,000,000 images). Our network achieves an AUC of 0.895 in predicting whether there is a…

Early detection of lung cancer has been proven to decrease mortality significantly. A recent development in computed tomography (CT), spectral CT, can potentially improve diagnostic accuracy, as it yields more information per scan than…

Computer Vision and Pattern Recognition · Computer Science 2020-07-01 Linde S. Hesse , Pim A. de Jong , Josien P. W. Pluim , Veronika Cheplygina

The advancement of computer-aided detection systems had a significant impact on clinical analysis and decision-making on human disease. Lung cancer requires more attention among the numerous diseases being examined because it affects both…

Image and Video Processing · Electrical Eng. & Systems 2023-05-24 Jafar Abdollahi

Statistical models for predicting lung cancer have the potential to facilitate earlier diagnosis of malignancy and avoid invasive workup of benign disease. Many models have been published, but comparative studies of their utility in…

Lung cancer, the second leading cause of cancer-related deaths, is primarily linked to long-term tobacco smoking (85% of cases). Surprisingly, 10-15% of cases occur in non-smokers. In 2020, approximately 2 million people were affected…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Imama Ajmi , Abhishek Das
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