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Characterization of lung nodules as benign or malignant is one of the most important tasks in lung cancer diagnosis, staging and treatment planning. While the variation in the appearance of the nodules remains large, there is a need for a…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Sarfaraz Hussein , Robert Gillies , Kunlin Cao , Qi Song , Ulas Bagci

Purpose: The lung nodules localization in CT scan images is the most difficult task due to the complexity of the arbitrariness of shape, size, and texture of lung nodules. This is a challenge to be faced when coming to developing different…

Image and Video Processing · Electrical Eng. & Systems 2023-01-06 Haytham Al Ewaidat , Youness El Brag

A computer-aided detection (CAD) system for the identification of pulmonary nodules in low-dose multi-detector helical Computed Tomography (CT) images with 1.25 mm slice thickness is presented. The basic modules of our lung-CAD system, a…

Discriminating lung nodules as malignant or benign is still an underlying challenge. To address this challenge, radiologists need computer aided diagnosis (CAD) systems which can assist in learning discriminative imaging features…

Computer Vision and Pattern Recognition · Computer Science 2018-10-15 Maria J. M. Chuquicusma , Sarfaraz Hussein , Jeremy Burt , Ulas Bagci

Recently, Computer-Aided Diagnosis (CAD) systems have emerged as indispensable tools in clinical diagnostic workflows, significantly alleviating the burden on radiologists. Nevertheless, despite their integration into clinical settings, CAD…

Image and Video Processing · Electrical Eng. & Systems 2024-06-27 Muwei Jian , Hongyu Chen , Zaiyong Zhang , Nan Yang , Haorang Zhang , Lifu Ma , Wenjing Xu , Huixiang Zhi

Lung cancer is the leading cause of patient mortality in the world. Early diagnosis of malignant pulmonary nodules in CT images can have a significant impact on reducing disease mortality and morbidity. In this work, we propose LMLCC-Net, a…

Image and Video Processing · Electrical Eng. & Systems 2025-11-27 Tasnia Binte Mamun , Adhora Madhuri , Nusaiba Sobir , Taufiq Hasan

The widespread adoption of CT has notably increased the number of detected lung nodules. However, current deep learning methods for classifying benign and malignant nodules often fail to comprehensively integrate global and local features,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Zhenchen Zhu , Ge Hu , Weixiong Tan , Kai Gao , Chao Sun , Zhen Zhou , Kepei Xu , Wei Han , Meixia Shang , Xiaoming Qiu , Yiqing Tan , Jinhua Wang , Zhoumeng Ying , Li Peng , Wei Song , Lan Song , Zhengyu Jin , Nan Hong , Yizhou Yu

Lung cancer is the most common form of cancer found worldwide with a high mortality rate. Early detection of pulmonary nodules by screening with a low-dose computed tomography (CT) scan is crucial for its effective clinical management.…

Image and Video Processing · Electrical Eng. & Systems 2020-06-17 Rakshith Sathish , Rachana Sathish , Ramanathan Sethuraman , Debdoot Sheet

Recent evolution in deep learning has proven its value for CT-based lung nodule classification. Most current techniques are intrinsically black-box systems, suffering from two generalizability issues in clinical practice. First,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-28 Hanxiao Zhang , Liang Chen , Xiao Gu , Minghui Zhang , Yulei Qin , Feng Yao , Zhexin Wang , Yun Gu , Guang-Zhong Yang

Lung cancer remains one of the leading causes of cancer-related mortality worldwide. Conventional computed tomography (CT) imaging, while essential for detection and staging, has limitations in distinguishing benign from malignant lesions…

Image and Video Processing · Electrical Eng. & Systems 2026-04-20 Baramee Sukumal , Aueaphum Aueawatthanaphisut

Lung cancer is one of the most deadly diseases in the world. Detecting such tumors at an early stage can be a tedious task. Existing deep learning architecture for lung nodule identification used complex architecture with large number of…

Image and Video Processing · Electrical Eng. & Systems 2020-09-25 Shah B. Shrey , Lukman Hakim , Muthusubash Kavitha , Hae Won Kim , Takio Kurita

Deep learning, as a promising new area of machine learning, has attracted a rapidly increasing attention in the field of medical imaging. Compared to the conventional machine learning methods, deep learning requires no hand-tuned feature…

Quantitative Methods · Quantitative Biology 2016-11-29 He Yang , Hengyong Yu , Ge Wang

Lung cancer classification in screening computed tomography (CT) scans is one of the most crucial tasks for early detection of this disease. Many lives can be saved if we are able to accurately classify malignant/cancerous lung nodules.…

Image and Video Processing · Electrical Eng. & Systems 2021-09-20 Mundher Al-Shabi , Kelvin Shak , Maxine Tan

Objective: In clinical practice, small lung nodules can be easily overlooked by radiologists. The paper aims to provide an efficient and accurate detection system for small lung nodules while keeping good performance for large nodules.…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Sunyi Zheng , Ludo J. Cornelissen , Xiaonan Cui , Xueping Jing , Raymond N. J. Veldhuis , Matthijs Oudkerk , Peter M. A. van Ooijen

Lung cancer, a leading cause of cancer-related deaths globally, emphasises the importance of early detection for better patient outcomes. Pulmonary nodules, often early indicators of lung cancer, necessitate accurate, timely diagnosis.…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Jiahao Lu , Chong Yin , Silvia Ingala , Kenny Erleben , Michael Bachmann Nielsen , Sune Darkner

A computer-aided detection (CAD) system for the identification of pulmonary nodules in low-dose multi-detector computed-tomography (CT) images has been developed in the framework of the MAGIC-5 Italian project. One of the main goals of this…

Nodule malignancy assessment is a complex, time-consuming and error-prone task. Current clinical practice requires measuring changes in size and density of the nodule at different time-points. State of the art solutions rely on 3D…

Image and Video Processing · Electrical Eng. & Systems 2020-05-27 Xavier Rafael-Palou , Anton Aubanell , Ilaria Bonavita , Mario Ceresa , Gemma Piella , Vicent Ribas , Miguel A. González Ballester

With the ongoing development of deep learning, an increasing number of AI models have surpassed the performance levels of human clinical practitioners. However, the prevalence of AI diagnostic products in actual clinical practice remains…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 Chenglong Wang , Yinqiao Yi , Yida Wang , Chengxiu Zhang , Yun Liu , Kensaku Mori , Mei Yuan , Guang Yang

Lung cancer is the second most common cancer and the leading cause of cancer-related deaths worldwide. Survival largely depends on tumor stage at diagnosis, and early detection with low-dose CT can significantly reduce mortality in…

Follow-up serves an important role in the management of pulmonary nodules for lung cancer. Imaging diagnostic guidelines with expert consensus have been made to help radiologists make clinical decision for each patient. However, tumor…

Image and Video Processing · Electrical Eng. & Systems 2020-10-12 Yamin Li , Jiancheng Yang , Yi Xu , Jingwei Xu , Xiaodan Ye , Guangyu Tao , Xueqian Xie , Guixue Liu