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This paper deals with a conserved phase field system that couples the energy balance equation with a Cahn--Hilliard type system including temperature and the inertial term for the order parameter. In the case without inertial term, the…

Analysis of PDEs · Mathematics 2025-05-28 Pierluigi Colli , Shunsuke Kurima

The global-in-time existence of weak solutions to a degenerate Cahn-Hilliard cross-diffusion system with singular potential in a bounded domain with no-flux boundary conditions is proved. The model consists of two coupled parabolic…

Analysis of PDEs · Mathematics 2024-01-11 Ansgar Jüngel , Yue Li

We analyze a diffuse interface model that describes the dynamics of incompressible two-phase flows influenced by interactions with a soluble chemical substance, encompassing the chemotaxis effect, mass transport, and reactions. In the…

Analysis of PDEs · Mathematics 2026-01-13 Andrea Giorgini , Jingning He , Hao Wu

Tumor growth has a number of features in common with a physical process known as molecular beam epitaxy. Both growth processes are characterized by the constraint of growth development to the body border, and surface diffusion of…

Quantitative Methods · Quantitative Biology 2009-11-13 Carlos Escudero

Cancer is a disease that takes millions of lives every year. Then, to propose treatments, avoid recurrence, and improve the patient's life quality, we need to analyze this disease from a biophysical perspective with a solid mathematical…

Quantitative Methods · Quantitative Biology 2024-07-09 Carlos M. Nieto , Oscar M. Pimentel , Fabio D. Lora-Clavijo

In this paper, we consider a stochastic version of the Cahn-Hilliard-Brinkman model in a smooth two- or three-dimensional domain with dynamical boundary conditions. The system describes creeping two-phase flows and is basically a coupling…

Probability · Mathematics 2026-01-13 Z. Brzeźniak , A. Ndongmo Ngana , T. Tachim Medjo

In this paper, we consider numerical approximations for the viscous Cahn-Hilliard equation with hyperbolic relaxation. This type of equations processes energy-dissipative structure. The main challenge in solving such a diffusive system…

Numerical Analysis · Mathematics 2017-12-18 Xiaofeng Yang , Jia Zhao

In this paper, we study a distributed optimal control problem for a diffuse interface model for tumor growth. The model consists of a Cahn-Hilliard type equation for the phase field variable coupled to a reaction diffusion equation for the…

Optimization and Control · Mathematics 2021-10-12 Matthias Ebenbeck , Patrik Knopf

In the present article the diffusion equation is used to model the spatio-temporal dynamics of a tumor, taking into account the heterogeneous of the medium. This approach makes it possible to take into account the complex geometric shape of…

Biological Physics · Physics 2023-02-07 Maxim V. Polyakov , Valeria V. Ten

Our aim in this article is to study a nonlinear viscoelastic Kirchhoff equation with strong damping, Balakrishnan-Taylor damping, nonlinear source and dynamical boundary condition. Firstly, we prove the local existence of solutions by using…

Analysis of PDEs · Mathematics 2015-06-09 Gang Li , Biqing Zhu , Danhua Wang

We prove the existence of large-data global-in-time weak solutions to an evolutionary PDE system describing flows of incompressible \emph{heat-conducting} viscoelastic rate-type fluids with stress-diffusion, subject to a stick-slip boundary…

Analysis of PDEs · Mathematics 2020-07-14 Miroslav Bulíček , Josef Málek , Vít Průša , Endre Süli

A uniform bounded variation estimate for finite volume approximations of the nonlinear scalar conservation law $\partial_t \alpha + \mathrm{div}(\boldsymbol{u}f(\alpha)) = 0$ in two and three spatial dimensions with an initial data of…

Numerical Analysis · Mathematics 2020-10-06 Gopikrishnan Chirappurathu Remesan

We propose a modeling framework for finite viscoelasticity, inspired by the kinematic assumption made by Green and Naghdi in plasticity. This approach fundamentally differs from the widely used multiplicative decomposition of the…

Numerical Analysis · Mathematics 2025-09-18 Ju Liu , Chongran Zhao , Jiashen Guan

In the present contribution we study the sliding mode control (SMC) problem for a diffuse interface tumor growth model coupling a viscous Cahn-Hilliard type equation for the phase variable with a reaction-diffusion equation for the…

Analysis of PDEs · Mathematics 2017-09-26 Pierluigi Colli , Gianni Gilardi , Gabriela Marinoschi , Elisabetta Rocca

We derive an effective one-dimensional limit from a three-dimensional Kelvin-Voigt model for viscoelastic thin-walled beams, in which the elastic and the viscous stress tensor comply with a frame-indifference principle. The limiting system…

Analysis of PDEs · Mathematics 2023-12-13 Manuel Friedrich , Lennart Machill

We propose a strange-attractor model of tumor growth and metastasis. It is a 4-dimensional spatio-temporal cancer model with strong nonlinear couplings. Even the same type of tumor is different in every patient both in size and appearance,…

Cell Behavior · Quantitative Biology 2008-10-28 Tijana T. Ivancevic , Murk J. Bottema , Lakhmi C. Jain

Williams and Bjerknes proposed a simple stochastic growth model to describe the tumor growth in the basal layer of an epithelium. In this work we generalize this model by including the possibility of saturation in the tumor growth as it is…

Condensed Matter · Physics 2007-05-23 S. C. Ferreira Junior

Variational phase-field models of brittle fracture are powerful tools for studying Griffith-type crack propagation in complex scenarios. However, as approximations of Griffith's theory-which does not incorporate a strength criterion-these…

Applied Physics · Physics 2026-01-06 Francesco Vicentini , Jonas Heinzmann , Pietro Carrara , Laura De Lorenzis

Microscale oxygenation plays a prominent role in tumour progression. Spatiotemporal variability of oxygen distribution in the tumour microenvironment contributes to cellular heterogeneity and to the emergence of normoxic and hypoxic…

Tissues and Organs · Quantitative Biology 2022-01-28 Jesús J. Bosque , Gabriel F. Calvo , María Cruz Navarro

This work concerns the continuum basis and numerical formulation for deformable materials with viscous dissipative mechanisms. We derive a viscohyperelastic modeling framework based on fundamental thermomechanical principles. Since most…

Numerical Analysis · Mathematics 2021-08-12 Ju Liu , Marcos Latorre , Alison L. Marsden