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As cannabis use has increased in recent years, researchers have come to rely on sophisticated machine learning models to predict cannabis use behavior and its impact on health. However, many artificial intelligence (AI) models lack…

Human-Computer Interaction · Computer Science 2025-03-11 Tongze Zhang , Tammy Chung , Anind Dey , Sang Won Bae

Although explainability is essential in the clinical diagnosis, most deep learning models still function as black boxes without elucidating their decision-making process. In this study, we investigate the explainable model development that…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Yunhe Gao , Difei Gu , Mu Zhou , Dimitris Metaxas

Deep neural networks for medical image classification often fail to generalize consistently in clinical practice due to violations of the i.i.d. assumption and opaque decision-making. This paper examines interpretability in deep neural…

Computer Vision and Pattern Recognition · Computer Science 2025-04-09 Mohammad Hossein Najafi , Mohammad Morsali , Mohammadreza Pashanejad , Saman Soleimani Roudi , Mohammad Norouzi , Saeed Bagheri Shouraki

Why do explainable AI (XAI) explanations in radiology, despite their promise of transparency, still fail to gain human trust? Current XAI approaches provide justification for predictions, however, these do not meet practitioners' needs.…

Human-Computer Interaction · Computer Science 2023-04-10 Robert Kaufman , David Kirsh

Explainability is key to enhancing artificial intelligence's trustworthiness in medicine. However, several issues remain concerning the actual benefit of explainable models for clinical decision-making. Firstly, there is a lack of consensus…

Image and Video Processing · Electrical Eng. & Systems 2023-12-18 Kazuma Kobayashi , Yasuyuki Takamizawa , Mototaka Miyake , Sono Ito , Lin Gu , Tatsuya Nakatsuka , Yu Akagi , Tatsuya Harada , Yukihide Kanemitsu , Ryuji Hamamoto

Artificial intelligence (AI) systems have substantially improved dermatologists' diagnostic accuracy for melanoma, with explainable AI (XAI) systems further enhancing clinicians' confidence and trust in AI-driven decisions. Despite these…

Interpretable deep learning is a fundamental building block towards safer AI, especially when the deployment possibilities of deep learning-based computer-aided medical diagnostic systems are so eminent. However, without a computational…

Machine Learning · Computer Science 2018-06-27 Anirban Mukhopadhyay

As interpretability has been pointed out as the obstacle to the adoption of Deep Neural Networks (DNNs), there is an increasing interest in solving a transparency issue to guarantee the impressive performance. In this paper, we demonstrate…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Woo-Jeoung Nam , Seong-Whan Lee

Recent success in Artificial Intelligence (AI) and Machine Learning (ML) allow problem solving automatically without any human intervention. Autonomous approaches can be very convenient. However, in certain domains, e.g., in the medical…

Artificial Intelligence · Computer Science 2021-03-03 Andreas Holzinger , André Carrington , Heimo Müller

Artificial intelligence (AI) generally and machine learning (ML) specifically demonstrate impressive practical success in many different application domains, e.g. in autonomous driving, speech recognition, or recommender systems. Deep…

Artificial Intelligence · Computer Science 2018-01-02 Andreas Holzinger , Chris Biemann , Constantinos S. Pattichis , Douglas B. Kell

Diagnosis based on medical images, such as X-ray images, often involves manual annotation of anatomical keypoints. However, this process involves significant human efforts and can thus be a bottleneck in the diagnostic process. To fully…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Jinhee Kim , Taesung Kim , Taewoo Kim , Jaegul Choo , Dong-Wook Kim , Byungduk Ahn , In-Seok Song , Yoon-Ji Kim

Nowadays, deep neural networks are widely used in mission critical systems such as healthcare, self-driving vehicles, and military which have direct impact on human lives. However, the black-box nature of deep neural networks challenges its…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Arun Das , Paul Rad

The increasing availability of large collections of electronic health record (EHR) data and unprecedented technical advances in deep learning (DL) have sparked a surge of research interest in developing DL based clinical decision support…

Machine Learning · Computer Science 2021-12-07 Di Jin , Elena Sergeeva , Wei-Hung Weng , Geeticka Chauhan , Peter Szolovits

Machine learning is frequently used in affective computing, but presents challenges due the opacity of state-of-the-art machine learning methods. Because of the impact affective machine learning systems may have on an individual's life, it…

Machine Learning · Computer Science 2025-10-07 David S. Johnson , Olya Hakobyan , Hanna Drimalla

The field of "explainable artificial intelligence" (XAI) seemingly addresses the desire that decisions of machine learning systems should be human-understandable. However, in its current state, XAI itself needs scrutiny. Popular methods…

Machine Learning · Computer Science 2026-04-09 Stefan Haufe , Rick Wilming , Benedict Clark , Rustam Zhumagambetov , Ahcène Boubekki , Jörg Martin , Danny Panknin

The complex nature of disease mechanisms and the variability of patient symptoms pose significant challenges in developing effective diagnostic tools. Although machine learning (ML) has made substantial advances in medical diagnosis, the…

In the world of medical diagnostics, the adoption of various deep learning techniques is quite common as well as effective, and its statement is equally true when it comes to implementing it into the retina Optical Coherence Tomography…

Image and Video Processing · Electrical Eng. & Systems 2022-03-03 Tasnim Sakib Apon , Mohammad Mahmudul Hasan , Abrar Islam , MD. Golam Rabiul Alam

Data-driven computational approaches have evolved to enable extraction of information from medical images with a reliability, accuracy and speed which is already transforming their interpretation and exploitation in clinical practice. While…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Tom Vercauteren , Mathias Unberath , Nicolas Padoy , Nassir Navab

There has been a significant surge of interest recently around the concept of explainable artificial intelligence (XAI), where the goal is to produce an interpretation for a decision made by a machine learning algorithm. Of particular…

Machine Learning · Computer Science 2019-10-31 Zhong Qiu Lin , Mohammad Javad Shafiee , Stanislav Bochkarev , Michael St. Jules , Xiao Yu Wang , Alexander Wong

Healthcare sector is totally different from other industry. It is on high priority sector and people expect highest level of care and services regardless of cost. It did not achieve social expectation even though it consume huge percentage…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Muhammad Imran Razzak , Saeeda Naz , Ahmad Zaib
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