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Malaria, childhood acute respiratory infection, and child undernutrition together account for over two million deaths annually in children under five, with the burden concentrated in low and middle-income countries where climate variability…

Applications · Statistics 2026-05-13 Usman Nazir , I-Han Cheng , Sara Khalid

Background: Overweight and obesity are an increasing phenomenon worldwide. Predicting future overweight or obesity early in the childhood reliably could enable a successful intervention by experts. While a lot of research has been done…

Machine Learning · Computer Science 2019-11-20 Ilkka Rautiainen , Sami Äyrämö

In adaptive clinical trials, the conventional end-of-trial point estimate of a treatment effect is prone to bias, that is, a systematic tendency to deviate from its true value. As stated in recent FDA guidance on adaptive designs, it is…

Childhood obesity is a major public health concern. Multidisciplinary pediatric weight management programs are considered standard treatment for children with obesity and severe obesity who are not able to be successfully managed in the…

Machine Learning · Computer Science 2022-03-08 Hamed Fayyaz , Thao-Ly T. Phan , H. Timothy Bunnell , Rahmatollah Beheshti

Background: Technology has provided a new way of life for adolescents. Strategies aimed at improving health behaviors through digital platforms can offer promising results. However, since peers can modify behaviors related to food and…

Human-Computer Interaction · Computer Science 2024-02-14 Carmen Benavides , José Alberto Benítez-Andrades , Pilar Marqués-Sánchez , Natalia Arias

Large-scale food fortification (LSFF) is a widely accepted intervention to alleviate micronutrient deficiencies, yet policy implementation is often incomplete and its effects on diet costs are not well established. We estimated the extent…

We introduce a model of molecular evolution in which the fitness of an individual depends both on its own and on the parent's genotype. The model can be solved by means of a nonlinear mapping onto the standard quasispecies model. The…

Biological Physics · Physics 2009-11-07 Claus O. Wilke

In the attention-deficit hyperactivity disorder (ADHD) study, children are prescribed different stimulant medications. The height measurements are recorded longitudinally along with the medication time. Differences among the patients are…

We consider the problem of individual-specific medication level recommendation (initiation, removal, increase, or decrease) for asthma sufferers. Asthma is one of the most common chronic diseases in both adults and children, affecting 8% of…

Applications · Statistics 2017-05-22 Curtis B Storlie , Megan E Branda , Michael R Gionfriddo , Nilay D Shah , Matthew A Rank

Diet plays a crucial role in health, and understanding the causal effects of dietary patterns is essential for informing public health policy and personalized nutrition strategies. However, causal inference in nutritional epidemiology faces…

Methodology · Statistics 2026-01-26 Dafne Zorzetto , Zizhao Xie , Julian Stamp , Arman Oganisian , Roberta De Vito

The predictive machine learning models for child mortality tend to be inaccurate when applied to future populations, since they suffer from look-ahead bias due to the randomization used in cross-validation. The Demographic and Health…

Machine Learning · Computer Science 2026-02-05 Md Muhtasim Munif Fahim , Md Rezaul Karim

The process of consumer decision-making is multidimensional, and price perception is a very important but still not well-understood dimension for both marketers and consumers. Although heuristics or mental shortcuts are seen as biased and…

General Economics · Economics 2025-06-26 Shawn Berry

Ethnic achievement gaps are often explained in terms of student and school factors. The decomposition of these gaps into their within- and between-school components has therefore been applied as a strategy to quantify the overall influence…

Applications · Statistics 2022-06-14 Beatriz Gallo Cordoba , George Leckie , William J. Browne

In the UK, US and elsewhere, school accountability systems increasingly compare schools using value-added measures of school performance derived from pupil scores in high-stakes standardised tests. Rather than naively comparing school…

Applications · Statistics 2018-11-26 George Leckie , Harvey Goldstein

One essential ingredient of evolutionary theory is the concept of fitness as a measure for a species' success in its living conditions. Here, we quantify the effect of environmental fluctuations onto fitness by analytical calculations on a…

Populations and Evolution · Quantitative Biology 2015-05-19 Anna Melbinger , Massimo Vergassola

Bunching of steps at the surface of growing crystals can be induced by both directions of the driving force: step up and step down. The processes happen in different adatom concentrations and differ in character. In this study we show how…

Materials Science · Physics 2020-01-24 Hristina Popova , Filip Krzyżewski , Magdalena Załuska-Kotur , Vesselin Tonchev

Estimating treatment effects for subgroups defined by post-treatment behavior (i.e., estimating causal effects in a principal stratification framework) can be technically challenging and heavily reliant on strong assumptions. We investigate…

Methodology · Statistics 2017-08-17 Luke Miratrix , Jane Furey , Avi Feller , Todd Grindal , Lindsay C. Page

This research analyses the axiomatic link among health expenditures, inflation rate, and gross national income (GNI) per capita concerning the child mortality (CMU5) rate in D-8 nations, employing panel data analysis from 1995 to 2014.…

Theoretical Economics · Economics 2026-01-06 M. Waseem Akram , Binita Shahi , M. Javed Akram

U.S. state education agencies mark schools displaying achievement gaps between demographic subgroups as needing improvement. Some schools may have few students in these subgroups, such that average end-of-year test scores only noisily…

Methodology · Statistics 2025-12-10 Joshua Wasserman , Michael R. Elliott , Ben B. Hansen

Although improving financial access is in the spotlight of the current U.S. health policy agenda, this alone does not address universal and comprehensive healthcare. Affordability is one barrier to healthcare, but others such as…

Applications · Statistics 2015-01-16 Mallory Nobles , Nicoleta Serban , Julie Swann