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Quantum optimization solvers typically rely on one-variable-to-one-qubit mapping. However, the low qubit count on current quantum computers is a major obstacle in competing against classical methods. Here, we develop a qubit-efficient…

Quantum Physics · Physics 2026-03-24 Bhuvanesh Sundar , Maxime Dupont

The quantum approximate optimization algorithm (QAOA) has proved to be an effective classical-quantum algorithm serving multiple purposes, from solving combinatorial optimization problems to finding the ground state of many-body quantum…

Quantum Physics · Physics 2022-03-08 P. Chandarana , N. N. Hegade , K. Paul , F. Albarrán-Arriagada , E. Solano , A. del Campo , Xi Chen

We study the protein folding problem on the base of the quantum approach we proposed recently by considering the model of protein chain with nine amino-acid residues. We introduced the concept of distance space and its projections on a…

Biological Physics · Physics 2021-06-24 Wen-Wen Mao , Li-Hua Lu , Yong-Yun Ji , You-Quan Li

Quantum approximate optimization algorithms are hybrid quantum-classical variational algorithms designed to approximately solve combinatorial optimization problems such as the MAX-CUT problem. In spite of its potential for near-term quantum…

Quantum Physics · Physics 2024-02-27 Eunok Bae , Soojoon Lee

The quantum approximate optimization algorithm (QAOA) is a prospective near-term quantum algorithm due to its modest circuit depth and promising benchmarks. However, an external parameter optimization required in QAOA could become a…

Quantum Physics · Physics 2022-01-26 Stefan H. Sack , Maksym Serbyn

The present tutorial aims to provide a comprehensible and easily accessible introduction into the theory and implementation of the famous Quantum Approximate Optimization Algorithm (QAOA). We lay our focus on practical aspects and…

Quantum Physics · Physics 2023-01-24 Andreas Sturm

We explore the potential application of quantum annealing to address the protein structure problem. To this end, we compare several proposed ab initio protein folding models for quantum computers and analyze their scaling and performance…

Quantum Physics · Physics 2026-04-27 Timon Scheiber , Matthias Heller , Andreas Giebel

The quantum approximate optimization algorithm (QAOA) is a promising method for solving certain classical combinatorial optimization problems on near-term quantum devices. When employing the QAOA to 3-SAT and Max-3-SAT problems, the quantum…

Quantum Physics · Physics 2023-06-07 Yunlong Yu , Chenfeng Cao , Xiang-Bin Wang , Nic Shannon , Robert Joynt

Quantum Approximate Optimization Algorithm (QAOA) enables solving combinatorial optimization problems on quantum computers by optimizing variational parameters for quantum circuits. We investigate a simplified approach that combines linear…

Quantum Physics · Physics 2025-05-26 Ryo Sakai , Hiromichi Matsuyama , Wai-Hong Tam , Yu Yamashiro

Variational Quantum optimization algorithms, such as the Variational Quantum Eigensolver (VQE) or the Quantum Approximate Optimization Algorithm (QAOA), are among the most studied quantum algorithms. In our work, we evaluate and improve an…

Quantum Physics · Physics 2022-10-24 David Winderl , Nicola Franco , Jeanette Miriam Lorenz

Combinatorial optimization problems are central to science and engineering and specialized hardware from quantum annealers to classical Ising machines are being actively developed to address them. These systems typically sample from a fixed…

The quantum approximate optimization algorithm (QAOA) is one of the most promising candidates for achieving quantum advantage through quantum-enhanced combinatorial optimization. Optimal QAOA parameter concentration effects for special…

Quantum Physics · Physics 2024-07-10 Jose Falla , Quinn Langfitt , Yuri Alexeev , Ilya Safro

Regression testing is key in verifying that software works correctly after changes. However, running the entire regression test suite can be impractical and expensive, especially for large-scale systems. Test suite optimization methods are…

Quantum Physics · Physics 2025-05-01 Antonio Trovato , Martin Beseda , Dario Di Nucci

While the ultimate goal of solving computationally intractable problems is to find a provably optimal solutions, practical constraints of real-world scenarios often necessitate focusing on efficiently obtaining high-quality, near-optimal…

Quantum Physics · Physics 2025-04-23 Prashanti Priya Angara , Emily Martins , Ulrike Stege , Hausi Müller

The syndrome decoding problem is known to be NP-complete. The goal of the decoder is to find an error of low weight that corresponds to a given syndrome obtained from a parity-check matrix. We use the quantum approximate optimization…

Quantum Physics · Physics 2024-11-21 Ching-Yi Lai , Kao-Yueh Kuo , Bo-Jyun Liao

The quantum approximate optimization algorithm (QAOA) is a method of approximately solving combinatorial optimization problems. While QAOA is developed to solve a broad class of combinatorial optimization problems, it is not clear which…

Quantum Physics · Physics 2020-08-13 James Ostrowski , Rebekah Herrman , Travis S. Humble , George Siopsis

We present a method to split quantum circuits of variational quantum algorithms (VQAs) to allow for parallel training and execution, that maximally exploits the limited number of qubits in hardware to solve large problem instances. We apply…

Quantum Physics · Physics 2023-04-07 Michele Cattelan , Sheir Yarkoni

Quantum computers are increasing in size and quality, but are still very noisy. Error mitigation extends the size of the quantum circuits that noisy devices can meaningfully execute. However, state-of-the-art error mitigation methods are…

Quantum Physics · Physics 2024-03-25 Stefan H. Sack , Daniel J. Egger

In recent years, quantum computing has emerged as a transformative force in the field of combinatorial optimization, offering novel approaches to tackling complex problems that have long challenged classical computational methods. Among…

Running quantum circuits on quantum computers does not always generate "clean" results, unlike on a simulator, as noise plays a significant role in any quantum device. To explore this, we experimented with the Quantum Approximate…

Quantum Physics · Physics 2025-10-09 Abyan Khabir Irfan , Chansu Yu
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