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Related papers: Neuron Growth Output-Feedback Control by PDE Backs…

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We take into account the influence of extracellular signalling on neurite elongation in a model of neurite growth mediated by building proteins (e.g. tubulin). Tubulin production dynamics was supplied by a function describing the influence…

Cell Behavior · Quantitative Biology 2013-11-20 Vasily Mironov , Alexander Romanov , Alexander Simonov , Maria Vedunova , Victor Kazantsev

This paper is concerned with the output feedback boundary stabilization of general 1-D reaction diffusion PDEs in the presence of an arbitrarily large input delay. We consider the cases of Dirichlet/Neumann/Robin boundary conditions for the…

Optimization and Control · Mathematics 2022-07-13 Hugo Lhachemi , Christophe Prieur

Geometrical cues are known to play a very important role in neuronal growth and the formation of neuronal networks. Here, we present a detailed analysis of axonal growth and dynamics for neuronal cells cultured on patterned…

Cell Behavior · Quantitative Biology 2019-06-14 Ilya Yurchenko , Joao Marcos Vensi Basso , Vladyslav Serhiiovych Syrotenko , Cristian Staii

This paper deals with the backstepping design of observer-based compensators for parabolic ODE-PDE-ODE systems. The latter consist of n coupled parabolic PDEs with distinct diffusion coefficients and spatially-varying coefficients, that are…

Systems and Control · Electrical Eng. & Systems 2020-08-28 Joachim Deutscher , Nicole Gehring

Neural operator approximations of the gain kernels in PDE backstepping has emerged as a viable method for implementing controllers in real time. With such an approach, one approximates the gain kernel, which maps the plant coefficient into…

Systems and Control · Electrical Eng. & Systems 2024-12-02 Luke Bhan , Yuanyuan Shi , Miroslav Krstic

Deep neural network approximation of nonlinear operators, commonly referred to as DeepONet, has proven capable of approximating PDE backstepping designs in which a single Goursat-form PDE governs a single feedback gain function. In boundary…

Optimization and Control · Mathematics 2024-07-04 Shanshan Wang , Mamadou Diagne , Miroslav Krstić

Neuronal damage, in the form of both brain and spinal cord injuries, is one of the major causes of disability and death in young adults worldwide. One way to assess the direct damage occurring after a mechanical insult is the simulation of…

Neural and Evolutionary Computing · Computer Science 2024-09-20 Antonio LaTorre , Man Ting Kwong , Julián A. García-Grajales , Riyi Shi , Antoine Jérusalem , José-María Peña

In this article, we detail the design of an output feedback stabilizing control law for an underactuated network of N subsystems of n + m heterodirectional linear first-order hyperbolic Partial Differential Equations interconnected through…

Analysis of PDEs · Mathematics 2024-09-17 Jean Auriol

An adaptive observer is proposed to estimate the synaptic distribution between neurons asymptotically from the measurement of a part of the neuronal activity and a delayed neural field evolution model. The convergence of the observer is…

Optimization and Control · Mathematics 2024-03-14 Lucas Brivadis , Antoine Chaillet , Jean Auriol

This paper presents an adaptive observer design for semilinear hyperbolic rolling contact ODE-PDE systems with uncertain friction characteristics parameterized by a matrix of unknown coefficients appearing in the nonlinear (and possibly…

Systems and Control · Electrical Eng. & Systems 2026-02-10 Luigi Romano , Ole Morten Aamo , Miroslav Krstić , Jan Åslund , Erik Frisk

We present a methodology for stabilization of general nonlinear systems with actuator dynamics governed by general, quasilinear, first-order hyperbolic PDEs. Since for such PDE-ODE cascades the speed of propagation depends on the PDE state…

Optimization and Control · Mathematics 2017-10-23 Nikolaos Bekiaris-Liberis , Miroslav Krstic

In this paper, we are concerned with the state feedback stabilization of ODE-PDE cascade systems governed by a linear ordinary differential equation and the 1-d reaction-diffusion equation posed on a bounded interval. In contrast to the…

Analysis of PDEs · Mathematics 2018-01-04 Habib Ayadi

This paper investigates the stabilization of a coupled system comprising a parabolic PDE and an elliptic PDE with nonlinear terms. A rigorous backstepping design provides an explicit boundary control law and exponentially convergent…

Analysis of PDEs · Mathematics 2025-07-18 Kamal Fenza , Moussa Labbadi , Mohamed Ouzahra

The pancreatic innervation undergoes dynamic remodeling during the development of pancreatic ductal adenocarcinoma (PDAC). Denervation experiments have shown that different types of axons can exert either pro- or anti-tumor effects, but…

Analysis of PDEs · Mathematics 2024-04-04 Marie-Jose Chaaya , Sophie Chauvet , Florence Hubert , Fanny Mann , Mathieu Mezache , Pierre Pudlo

Axons are linear processes of nerve cells that can range from a few tens of micrometers up to meters in length. In addition to external cues, the length of an axon is also regulated by unknown internal mechanisms. Molecular motors have been…

Subcellular Processes · Quantitative Biology 2019-05-15 Frederic Folz , Lukas Wettmann , Giovanna Morigi , Karsten Kruse

We introduce a framework for eliminating the computation of controller gain functions in PDE control. We learn the nonlinear operator from the plant parameters to the control gains with a (deep) neural network. We provide closed-loop…

Systems and Control · Electrical Eng. & Systems 2023-03-01 Luke Bhan , Yuanyuan Shi , Miroslav Krstic

This paper proposes an adaptive neural network-based backstepping controller that uses rigid graph theory to address the distance-based formation control problem and target tracking for nonlinear multi-agent systems with bounded time-delay…

Systems and Control · Electrical Eng. & Systems 2020-10-13 Kiarash Aryankia , Rastko R. Selmic

We propose a partial differential-integral equation (PDE) framework for deep neural networks (DNNs) and their associated learning problem by taking the continuum limits of both network width and depth. The proposed model captures the…

Optimization and Control · Mathematics 2024-11-12 Peter Markowich , Simone Portaro

Neuronal circuits arise as axons and dendrites extend, navigate, and connect to target cells. Axonal growth, in particular, integrates deterministic guidance from substrate mechanics and geometry with stochastic fluctuations generated by…

Biological Physics · Physics 2025-10-10 Cristian Staii

A magnetizable piezoelectric beam model, free at both ends, is considered. Piezoelectric materials have a strong interaction of electromagnetic and acoustic waves, whose wave propagation speeds differ substantially. The corresponding…

Analysis of PDEs · Mathematics 2024-03-14 Ahmet Ozkan Ozer , Uthman Rasaq , Ibrahim Khalilullah