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The integration of knowledge extracted from diverse models, whether described by domain experts or generated by machine learning algorithms, has historically been challenged by the absence of a suitable framework for specifying and…

Artificial Intelligence · Computer Science 2024-04-03 Carlos Leandro

Simulation has become an essential component of designing and developing scientific experiments. The conventional procedural approach to coding simulations of complex experiments is often error-prone, hard to interpret, and inflexible,…

Computational Physics · Physics 2023-08-09 Peter Sun , John A. Marohn

Modeling and forecasting the spread of infectious diseases is essential for effective public health decision-making. Traditional epidemiological models rely on expert-defined frameworks to describe complex dynamics, while neural networks,…

Machine Learning · Computer Science 2024-12-31 Jianda Du , Senwei Liang , Chunmei Wang

Abstraction is essential for reducing the complexity of systems across diverse fields, yet designing effective abstraction methodology for probabilistic models is inherently challenging due to stochastic behaviors and uncertainties. Current…

Artificial Intelligence · Computer Science 2025-03-03 Nijesh Upreti , Vaishak Belle

This document analyzes the role of data-driven methodologies in Covid-19 pandemic. We provide a SWOT analysis and a roadmap that goes from the access to data sources to the final decision-making step. We aim to review the available…

Populations and Evolution · Quantitative Biology 2020-06-11 Teodoro Alamo , D. G. Reina , Pablo Millán

Epidemic models study the spread of an undesired agent through a population, be it infectious diseases through a country, misinformation in online social media, or pests infesting a region. In combating these epidemics, we rely neither on…

Compositional generalization -- the ability to understand and generate novel combinations of learned concepts -- enables models to extend their capabilities beyond limited experiences. While effective, the data structures and principles…

Machine Learning · Computer Science 2025-12-12 Lingjing Kong , Shaoan Xie , Yang Jiao , Yetian Chen , Yanhui Guo , Simone Shao , Yan Gao , Guangyi Chen , Kun Zhang

This article reviews and presents various solved and open problems in the development, analysis, and control of epidemic models. We are interested in presenting a relatively concise report for new engineers looking to enter the field of…

Optimization and Control · Mathematics 2015-08-26 Cameron Nowzari , Victor M. Preciado , George J. Pappas

To be fully useful for public health practice, models for epidemic response must be able to do more than predict -- it is also important to incorporate the mechanisms underlying transmission dynamics to enable policymakers and practitioners…

Quantitative Methods · Quantitative Biology 2025-05-26 Jiale Tan , Marisa C. Eisenberg

Advanced epidemic forecasting is critical for enabling precision containment strategies, highlighting its strategic importance for public health security. While recent advances in Large Language Models (LLMs) have demonstrated effectiveness…

Machine Learning · Computer Science 2025-05-20 Chenghua Gong , Rui Sun , Yuhao Zheng , Juyuan Zhang , Tianjun Gu , Liming Pan , Linyuan Lv

Estimates from infectious disease models have constituted a significant part of the scientific evidence used to inform the response to the COVID-19 pandemic in the UK. These estimates can vary strikingly in their bias and variability.…

Applications · Statistics 2022-10-12 R. E. Moore , C. Rosato , S. Maskell

Epidemiological early warning systems for dengue fever rely on up-to-date epidemiological data to forecast future incidence. However, epidemiological data typically requires time to be available, due to the application of time-consuming…

Social and Information Networks · Computer Science 2017-05-23 Julio Albinati , Wagner Meira , Gisele L. Pappa , Mauro Teixeira , Cecilia Marques-Toledo

Contact (or mixing, or more generally connectivity) matrices are a fundamental component of modelling and inference for infectious disease epidemiology. Their structure and parametrisation directly accounts for the frequency of interactions…

This paper gives an introduction to rule-based modelling applied to topics in infectious diseases. Rule-based models generalise reaction-based models with reagents that have internal state and may be bound together to form complexes, as in…

Populations and Evolution · Quantitative Biology 2021-08-10 William Waites , Matteo Cavaliere , David Manheim , Jasmina Panovska-Griffiths , Vincent Danos

The modeling of the spreading of communicable diseases has experienced significant advances in the last two decades or so. This has been possible due to the proliferation of data and the development of new methods to gather, mine and…

Physics and Society · Physics 2020-09-09 Alberto Aleta , Guilherme Ferraz de Arruda , Yamir Moreno

Temporal networks of face-to-face interactions between individuals are useful proxies of the dynamics of social systems on fast time scales. Several empirical statistical properties of these networks have been shown to be robust across a…

Physics and Society · Physics 2023-02-03 Didier Le Bail , Mathieu Génois , Alain Barrat

Modern generative models exhibit unprecedented capabilities to generate extremely realistic data. However, given the inherent compositionality of the real world, reliable use of these models in practical applications requires that they…

Machine Learning · Computer Science 2025-07-29 Maya Okawa , Ekdeep Singh Lubana , Robert P. Dick , Hidenori Tanaka

Systems biology models are useful models of complex biological systems that may require a large amount of experimental data to fit each model's parameters or to approximate a likelihood function. These models range from a few to thousands…

Quantitative Methods · Quantitative Biology 2024-07-12 Vincent D. Zaballa , Elliot E. Hui

In recent years the research community has accumulated overwhelming evidence for the emergence of complex and heterogeneous connectivity patterns in a wide range of biological and sociotechnical systems. The complex properties of real-world…

Physics and Society · Physics 2015-09-21 Romualdo Pastor-Satorras , Claudio Castellano , Piet Van Mieghem , Alessandro Vespignani

We propose a novel model-based clustering approach for samples of time series. We assume as a unique commonality that two observations belong to the same group if structural changes in their behaviours happen at the same time. We resort to…

Methodology · Statistics 2024-10-15 Riccardo Corradin , Luca Danese , Wasiur R. KhudaBukhsh , Andrea Ongaro