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The COVID-19 crisis has shown that we can only prevent the risk of mass contagion through timely, large-scale, coordinated, and decisive actions. However, frequently the models used by experts [from whom decision-makers get their main…

Applications · Statistics 2021-03-08 Mauricio Herrera

The COVID-19 pandemic began over two years ago, yet schools, businesses, and other organizations are still struggling to keep the risk of disease outbreak low while returning to (near) normal functionality. Observations from these past…

Populations and Evolution · Quantitative Biology 2022-02-02 Sarah C. Fay , Dalton J. Jones , Munther A. Dahleh , A. E. Hosoi

This paper presents a detailed mathematical investigation into the dynamics of COVID-19 infections through extended Susceptible-Infected-Recovered (SIR) and Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological models. By…

Populations and Evolution · Quantitative Biology 2025-05-21 Caleb Traxler , Minh Ton , Nameer Ahmed , Sasha Prostota , Annie Cheng

Social distancing strategies have been adopted by governments to manage the COVID-19 pandemic, since the first outbreak began. However, further epidemic waves keep out the return of economic and social activities to their standard levels of…

Optimization and Control · Mathematics 2021-06-07 J. E. Sereno , A. D' Jorge , A. Ferramosca , E. A. Hernandez-Vargas , A. H. Gonzalez

This work introduces a novel epidemiological model that simultaneously considers multiple viral strains, reinfections due to waning immunity response over time and an optimal control formulation. This enables us to derive optimal mitigation…

Systems and Control · Electrical Eng. & Systems 2021-09-10 Edilson F. Arruda , Dayse H. Pastore , Clauda M. Dias , Shyam S. Das

It is well recognized that population heterogeneity plays an important role in the spread of epidemics. While individual variations in social activity are often assumed to be persistent, i.e. constant in time, here we discuss the…

Populations and Evolution · Quantitative Biology 2021-02-22 Alexei V. Tkachenko , Sergei Maslov , Tong Wang , Ahmed Elbanna , George N. Wong , Nigel Goldenfeld

While many efforts are currently devoted to vaccines development and administration, social distancing measures, including severe restrictions such as lockdowns, remain fundamental tools to contain the spread of COVID-19. A crucial point…

Systems and Control · Electrical Eng. & Systems 2021-09-03 Mauro Bisiacco , Gianluigi Pillonetto

COVID-19 has resulted in a public health global crisis. The pandemic control necessitates epidemic models that capture the trends and impacts on infectious individuals. Many exciting models can implement this but they lack practical…

Computers and Society · Computer Science 2021-04-13 Ou Deng , Kiichi Tago , Qun Jin

A compartmental epidemic model is proposed to predict the Covid-19 virus spread. It considers: both detected and undetected infected populations, medical quarantine and social sequestration, release from sequestration, plus possible…

Populations and Evolution · Quantitative Biology 2020-07-10 Zeina S. Khan , Frank Van Bussel , Fazle Hussain

Susceptible-Invective-Recovered (SIR) mathematical models are in high demand due to the COVID-19 pandemic. They are used in their standard formulation, or through the many variants, trying to fit and hopefully predict the number of new…

Populations and Evolution · Quantitative Biology 2020-05-19 Ben-Hur Francisco Cardoso , Sebastián Gonçalves

The COVID-19 pandemic left its unique mark on the 21st century as one of the most significant disasters in history, triggering governments all over the world to respond with a wide range of interventions. However, these restrictions come…

Computational Engineering, Finance, and Science · Computer Science 2021-06-02 Assem Zhunis , Tung-Duong Mai , Sundong Kim

The COVID-19 epidemic has swept the world for over a year. However, a large number of infectious asymptomatic COVID-19 cases (\textit{ACC}s) are still making the breaking up of the transmission chains very difficult. Efforts by…

Social and Information Networks · Computer Science 2021-10-26 Yue Hu , Budhitama Subagdja , Ah-Hwee Tan , Chai Quek , Quanjun Yin

The ongoing COVID-19 pandemic continues to affect communities around the world. To date, almost 6 million people have died as a consequence of COVID-19, and more than one-quarter of a billion people are estimated to have been infected…

Epidemiological simulations as a method are used to better understand and predict the spreading of infectious diseases, for example of COVID-19. This paper presents an approach that combines person-centric data-driven human mobility…

Severe acute respiratory disease SARS-CoV-2 has had a found impact on public health systems and healthcare emergency response especially with respect to making decisions on the most effective measures to be taken at any given time. As…

Machine Learning · Computer Science 2023-09-19 Charithea Stylianides , Kleanthis Malialis , Panayiotis Kolios

An urgent problem in controlling COVID-19 spreading is to understand the role of undocumented infection. We develop a five-state model for COVID-19, taking into account the unique features of the novel coronavirus, with key parameters…

Populations and Evolution · Quantitative Biology 2020-03-27 Yong-Shang Long , Zheng-Meng Zhai , Li-Lei Han , Jie Kang , Yi-Lin Li , Zhao-Hua Lin , Lang Zeng , Da-Yu Wu , Chang-Qing Hao , Ming Tang , Zonghua Liu , Ying-Cheng Lai

During the COVID-19 pandemic, the behavioral response to reported case numbers changed drastically over time. While a few dozen cases were enough to trigger government-induced and voluntary contact reduction in early 2020, less than a year…

Physics and Society · Physics 2023-09-27 Bastian Heinlein , Manlio De Domenico

In this paper, we propose a continuous-time stochastic intensity model, namely, two-phase dynamic contagion process(2P-DCP), for modelling the epidemic contagion of COVID-19 and investigating the lockdown effect based on the dynamic…

Physics and Society · Physics 2020-06-30 Zezhun Chen , Angelos Dassios , Valerie Kuan , Jia Wei Lim , Yan Qu , Budhi Surya , Hongbiao Zhao

Repeated decision-making problems under uncertainty may arise in the health policy context, such as infectious disease control for COVID-19 and other epidemics. These problems may sometimes be effectively solved using Markov decision…

Optimization and Control · Mathematics 2024-11-28 Suyanpeng Zhang , Sze-chuan Suen

Motivated by the increasing number of COVID-19 cases that have been observed in many countries after the vaccination and relaxation of non-pharmaceutical interventions, we propose a mathematical model on time-varying networks for the spread…

Dynamical Systems · Mathematics 2022-03-09 Kathinka Frieswijk , Lorenzo Zino , Ming Cao