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Large audio and language models have recently demonstrated zero-shot reasoning capabilities across various domains. However, it remains unclear how the form of audio input, whether handcrafted acoustic features extracted from speech or the…

Sound · Computer Science 2026-05-26 Muhammad Ashad Kabir , Sirajam Munira

Evaluating neurological disorders such as Parkinson's disease (PD) is a challenging task that requires the assessment of several motor and non-motor functions. In this paper, we present an end-to-end deep learning framework to measure PD…

Computer Vision and Pattern Recognition · Computer Science 2020-12-25 Amirhossein Dadashzadeh , Alan Whone , Michal Rolinski , Majid Mirmehdi

A transcriptome-wide blood expression dataset of Parkinson's disease (PD) patients and controls was analyzed under the hypothesis-rich mathematical framework. The analysis pointed towards differential expression in blood cells in many of…

Cell Behavior · Quantitative Biology 2010-03-30 André X. C. N. Valente , Jorge A. B. Sousa , Tiago F. Outeiro , Lino Ferreira

Falls are common in people with Parkinson's disease (PD) and have detrimental effects which can lower the quality of life. While studies have been conducted to learn about falling in general, factors distinguishing injurious from…

Applications · Statistics 2019-10-08 Sarini Abdullah , James McGree , Nicole White , Kerrie Mengersen , Graham Kerr

Parkinson's Disease (PD) is a neurodegenerative disorder that significantly impacts motor and non-motor functions. There is currently no treatment that slows or stops neurodegeneration in PD. In this context, assistive technologies (ATs)…

Human-Computer Interaction · Computer Science 2025-05-27 Subek Acharya , Sansrit Paudel

Resting-state EEG (rs-EEG) has been demonstrated to aid in Parkinson's disease (PD) diagnosis. In particular, the power spectral density (PSD) of low-frequency bands ({\delta} and {\theta}) and high-frequency bands ({\alpha} and \b{eta})…

Signal Processing · Electrical Eng. & Systems 2023-03-03 Anna Kurbatskaya , Alberto Jaramillo-Jimenez , John Fredy Ochoa-Gomez , Kolbjørn Brønnick , Alvaro Fernandez-Quilez

Deep learning holds tremendous potential in healthcare for uncovering hidden patterns within extensive clinical datasets, aiding in the diagnosis of various diseases. Parkinson's disease (PD) is a neurodegenerative condition characterized…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Aqib Nazir Mir , Iqra Nissar , Mumtaz Ahmed , Sarfaraz Masood , Danish Raza Rizvi

Changes in speech and language are among the first signs of Parkinson's disease (PD). Thus, clinicians have tried to identify individuals with PD from their voices for years. Doctors can leverage AI-based speech assessments to spot PD…

Sound · Computer Science 2023-12-06 Mahboobeh Parsapoor

Parkinson's Disease (PD) is a neurological disorder that affects facial movements and non-verbal communication. Patients with PD present a reduction in facial movements called hypomimia which is evaluated in item 3.2 of the MDS-UPDRS-III…

Computer Vision and Pattern Recognition · Computer Science 2020-12-14 Luis Felipe Gomez-Gomez , Aythami Morales , Julian Fierrez , Juan Rafael Orozco-Arroyave

A widely used test for the diagnosis of Parkinson's disease (PD) and Essential tremor (ET) is hand-drawn shapes,where the analysis is observationally performed by the examining neurologist. This method is subjective and is prone to bias…

Computer Vision and Pattern Recognition · Computer Science 2020-06-23 Nabeel Seedat , Vered Aharonson , Ilana Schlesinger

Developing objective methods for assessing the severity of Parkinson's disease (PD) is crucial for improving the diagnosis and treatment. This study proposes two sets of novel features derived from the single frequency filtering (SFF)…

Audio and Speech Processing · Electrical Eng. & Systems 2023-08-21 Sudarsana Reddy Kadiri , Manila Kodali , Paavo Alku

Parkinson's disease (PD) is a neurodegenerative condition characterized by frequently changing motor symptoms, necessitating continuous symptom monitoring for more targeted treatment. Classical time series classification and deep learning…

Machine Learning · Computer Science 2025-06-03 Cedric Donié , Neha Das , Satoshi Endo , Sandra Hirche

Parkinson's disease is a progressive and slowly developing neurodegenerative disease, characterized by dopaminergic neuron loss in the substantia nigra region of the brain. Despite extensive research by scientists, there is not yet a cure…

Quantitative Methods · Quantitative Biology 2024-08-31 Pratham Kankariya , Rachita Rode , Kevin Mudaliar , Pranali Hatode

Parkinson's disease is a neurodegenerative disorder that can be very tricky to diagnose and treat. Such early symptoms can include tremors, wheezy breathing, and changes in voice quality as critical indicators of neural damage. Notably,…

Sound · Computer Science 2025-11-20 Abishek Karthik , Pandiyaraju V , Dominic Savio M , Rohit Swaminathan S

Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide, yet there is no disease-modifying therapy up to this date. The biological complexity underlying PD hampers the investigation of the principal…

Dynamical Systems · Mathematics 2022-12-22 Elena Righetti , Alice Antonello , Luca Marchetti , Enrico Domenici , Federico Reali

Parkinson's disease (PD) is a progressive disorder in which symptom burden and functional impairment evolve over time, making severity staging essential for clinical monitoring and treatment planning. However, many computational studies…

Machine Learning · Computer Science 2026-04-21 Md Mezbahul Islam , John Michael Templeton , Christian Poellabauer , Ananda Mohan Mondal

Parkinson's disease is a widespread neurodegenerative condition necessitating early diagnosis for effective intervention. This paper introduces an innovative method for diagnosing Parkinson's disease through the analysis of human EEG…

Signal Processing · Electrical Eng. & Systems 2024-05-03 Maryam Allahbakhshi , Aylar Sadri , Seyed Omid Shahdi

Electroencephalography has been established as an effective method for detecting Parkinson's disease, typically diagnosed early.Current Parkinson's disease detection methods have shown significant success within individual datasets,…

Machine Learning · Computer Science 2025-08-21 Qian Zhang , Ruilin Zhang , Biaokai Zhu , Xun Han , Jun Xiao , Yifan Liu , Zhe Wang

Parkinson's disease is a common neurological disease, entailing a multitude of motor deficiency symptoms. In this project, we developed a device with an uploaded edge machine learning algorithm that can detect the onset of freezing of gait…

Signal Processing · Electrical Eng. & Systems 2022-11-15 Purnoor Ghuman , Tyama Lyall , Usama Mahboob , Alia Aamir , Xilin Liu

Regular and stochastic behavior in the time series of Parkinsonian pathological tremor velocity is studied on the basis of the statistical theory of discrete non-Markov stochastic processes and flicker-noise spectroscopy. We have developed…