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The joint design of the optical system and the downstream algorithm is a challenging and promising task. Due to the demand for balancing the global optimal of imaging systems and the computational cost of physical simulation, existing…

We present a novel computational paradigm for process design in manufacturing processes that incorporates simulation responses to optimize manufacturing process parameters in high-dimensional temporal and spatial design spaces. We developed…

Computational Engineering, Finance, and Science · Computer Science 2021-07-26 Mojtaba Mozaffar , Jian Cao

Interferometry provides highly sensitive access to optical phase and is central to much of modern metrology and phase imaging methods. Conventional implementations, however, often face trade-offs between mechanical stability and…

Phase retrieval refers to the problem of recovering an image from the magnitudes of its complex-valued linear measurements. Since the problem is ill-posed, the recovery requires prior knowledge on the unknown image. We present DOLPH as a…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Shirin Shoushtari , Jiaming Liu , Ulugbek S. Kamilov

Several strategies in phase retrieval are unified by an iterative "difference map" constructed from a pair of elementary projections and a single real parameter $\beta$. For the standard application in optics, where the two projections…

Numerical Analysis · Mathematics 2025-10-20 Veit Elser

In this paper, we develop a novel phase retrieval approach to reconstruct x-ray differential phase shift induced by an object. A primary advantage of our approach is a higher-order accuracy over that with the conventional linear…

Medical Physics · Physics 2010-03-18 Wenxiang Cong , Ge Wang

Photonic device development (PDD) has achieved remarkable success in designing and implementing new devices for controlling light across various wavelengths, scales, and applications, including telecommunications, imaging, sensing, and…

End-to-end optimization, which simultaneously optimizes optics and algorithms, has emerged as a powerful data-driven method for computational imaging system design. This method achieves joint optimization through backpropagation by…

Computer Vision and Pattern Recognition · Computer Science 2025-08-08 Chi-Jui Ho , Yash Belhe , Steve Rotenberg , Ravi Ramamoorthi , Tzu-Mao Li , Nicholas Antipa

Deep neural networks have emerged as effective tools for computational imaging including quantitative phase microscopy of transparent samples. To reconstruct phase from intensity, current approaches rely on supervised learning with training…

Image and Video Processing · Electrical Eng. & Systems 2020-01-28 Emrah Bostan , Reinhard Heckel , Michael Chen , Michael Kellman , Laura Waller

We present a novel diffractive imaging method that harnesses a low-resolution real-space image to guide the phase retrieval. A computational algorithm is developed to utilize such prior knowledge as a real-space constraint in the iterative…

Optics · Physics 2020-10-27 Po-Nan Li , Soichi Wakatsuki , Piero A. Pianetta , Yijin Liu

Artificial RNA molecules with novel functionality have many applications in synthetic biology, pharmacy and white biotechnology. The de novo design of such devices using computational methods and prediction tools is a resource-efficient…

Biomolecules · Quantitative Biology 2019-05-13 Stefan Hammer , Christian Günzel , Mario Mörl , Sven Findeiß

We introduce a method that automatically and jointly updates both continuous and discrete parameters of a compound lens design, to improve its performance in terms of sharpness, speed, or both. Previous methods for compound lens design use…

Graphics · Computer Science 2025-09-30 Arjun Teh , Delio Vicini , Bernd Bickel , Ioannis Gkioulekas , Matthew O'Toole

Application-specific optical processors have been considered disruptive technologies for modern computing that can fundamentally accelerate the development of artificial intelligence (AI) by offering substantially improved computing…

Image and Video Processing · Electrical Eng. & Systems 2021-05-26 Tiankuang Zhou , Xing Lin , Jiamin Wu , Yitong Chen , Hao Xie , Yipeng Li , Jintao Fan , Huaqiang Wu , Lu Fang , Qionghai Dai

A general mathematical framework and recovery algorithm is presented for the holographic phase retrieval problem. In this problem, which arises in holographic coherent diffraction imaging, a "reference" portion of the signal to be recovered…

Information Theory · Computer Science 2024-12-20 David A. Barmherzig , Ju Sun , T. J. Lane , Po-Nan Li , Emmanuel J. Candès

Through digital imaging, microscopy has evolved from primarily being a means for visual observation of life at the micro- and nano-scale, to a quantitative tool with ever-increasing resolution and throughput. Artificial intelligence, deep…

Programmable photonic integrated circuits (PICs), offering diverse signal processing functions within a single chip, are promising solutions for applications ranging from optical communications to artificial intelligence. While the scale…

Critical aspects of computational imaging systems, such as experimental design and image priors, can be optimized through deep networks formed by the unrolled iterations of classical model-based reconstructions (termed physics-based…

Computer Vision and Pattern Recognition · Computer Science 2020-03-13 Michael Kellman , Kevin Zhang , Jon Tamir , Emrah Bostan , Michael Lustig , Laura Waller

Optical microscopy has been employed to derive salient characteristics of an object in various fields, including cell biology, flow cytometry, biopsy, and neuroscience. In particular, measuring the phase of light scattered from an object…

Optics · Physics 2025-03-18 Jeonghun Oh , Herve Hugonnet , Weisun Park , YongKeun Park

We perform quantitative phase imaging using phase retrieval to implement synthetic aperture imaging. Compared to digital holography, the developed technique is simpler, less expensive, and more stable.

Optics · Physics 2016-09-07 Dennis J. Lee , Andrew M. Weiner

Computer-automated design and discovery have led to high-performance nanophotonic devices with diverse functionalities. However, massively multi-channel systems such as metasurfaces controlling many incident angles and photonic-circuit…

Applied Physics · Physics 2024-06-05 Shiyu Li , Ho-Chun Lin , Chia Wei Hsu