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Deep optical optimization has recently emerged as a new paradigm for designing computational imaging systems using only the output image as the objective. However, it has been limited to either simple optical systems consisting of a single…

Computer Vision and Pattern Recognition · Computer Science 2024-08-08 Xinge Yang , Qiang Fu , Wolfgang Heidrich

Reconstructing high-quality magnetic resonance images (MRI) from undersampled raw data is of great interest from both technical and clinical point of views. To this date, however, it is still a mathematically and computationally challenging…

Numerical Analysis · Mathematics 2021-09-01 T. Schmoderer , A. I Aviles-Rivero , V. Corona , N. Debroux , C-B. Schönlieb

Quantitative phase imaging has become a topic of considerable interest in the microscopy community. We have recently described one such technique based on the use of a partitioned detection aperture, which can be operated in a single shot…

Optics · Physics 2015-10-20 Roman Barankov , Jean-Charles Baritaux , Jerome Mertz

Optical devices lie at the heart of most of the technology we see around us. When one actually wants to make such an optical device, one can predict its optical behavior using computational simulations of Maxwell's equations. If one then…

Machine Learning · Computer Science 2022-02-09 Joeri Lenaerts , Hannah Pinson , Vincent Ginis

Microscopes are vital pieces of equipment in much of biological research and medical diagnostics. However, access to a microscope can represent a bottleneck in research, especially in lower-income countries. `Smart' computer controlled…

Instrumentation and Detectors · Physics 2022-07-08 Samuel McDermott , Filip Ayazi , Joel Collins , Joe Knapper , Julian Stirling , Richard Bowman , Pietro Cicuta

We present a novel learning-based method to build a differentiable computational model of a real fluorescence microscope. Our model can be used to calibrate a real optical setup directly from data samples and to engineer point spread…

Image and Video Processing · Electrical Eng. & Systems 2023-06-12 Josue Page , Paolo Favaro

In the last five decades, iterative phase retrieval methods draw large amount of interest across the research community as a non-interferometric approach to recover quantitative phase distributions from one (or more) intensity measurement.…

Optics · Physics 2020-07-21 Nathaniel Hai , Joseph Rosen

In computational imaging, hardware for signal sampling and software for object reconstruction are designed in tandem for improved capability. Examples of such systems include computed tomography (CT), magnetic resonance imaging (MRI), and…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Andrew Olsen , Yolanda Hu , Vidya Ganapati

Poor access to eye care is a major global challenge that could be ameliorated by low-cost, portable, and easy-to-use diagnostic technologies. Diffuser-based imaging has the potential to enable inexpensive, compact optical systems that can…

Medical Physics · Physics 2020-06-23 Yunzhe Li , Gregory N. McKay , Nicholas J. Durr , Lei Tian

Adaptive optics can be used to mitigate the effects of atmospheric turbulence on imaging systems, but the correction is only partial, and deconvolution is often required to improve the resolution. This results in entire optical/digital…

Instrumentation and Methods for Astrophysics · Physics 2026-02-09 Florian Cheyssial , Laurent Mugnier , Cyril Petit

Optical multilayer thin film structures have been widely used in numerous photonic domains and applications. The key component to enable these applications is the inverse design. Different from other photonic structures such as metasurface…

Optics · Physics 2024-09-27 Taigao Ma , Mingqian Ma , L. Jay Guo

This paper develops a novel framework for phase retrieval, a problem which arises in X-ray crystallography, diffraction imaging, astronomical imaging and many other applications. Our approach combines multiple structured illuminations…

Information Theory · Computer Science 2011-09-21 Emmanuel J. Candes , Yonina Eldar , Thomas Strohmer , Vlad Voroninski

The ability to design passive structures that perform different operations on different electromagnetic fields is key to many technologies, from beam-steering to optical computing. While many techniques have been developed to optimise…

Applied Physics · Physics 2022-11-28 J. R. Capers , S. J. Boyes , A. P. Hibbins , S. A. R. Horsley

We propose and experimentally demonstrate a differential microscopy method to obtain simultaneous amplitude, phase, and quantitative polarization gradient imaging in a single experimental embodiment. A full-field optical spatial…

Optics · Physics 2023-10-11 Jeeban Kumar Nayak , Niladri Modak , Sayan Ghosh , Nirmalya Ghosh

We demonstrate that a deep neural network can significantly improve optical microscopy, enhancing its spatial resolution over a large field-of-view and depth-of-field. After its training, the only input to this network is an image acquired…

Machine Learning · Computer Science 2017-11-21 Yair Rivenson , Zoltan Gorocs , Harun Gunaydin , Yibo Zhang , Hongda Wang , Aydogan Ozcan

Diffractive lenses have recently been applied to the domain of multispectral imaging in the X-ray and UV regimes where they can achieve very high resolution as compared to reflective and refractive optics. Conventionally, spectral…

Image and Video Processing · Electrical Eng. & Systems 2020-05-26 Evan Widloski , Ulas Kamaci , Farzad Kamalabadi

As a revolutionary observation tool in life science, biomedical, and material science, optical microscopy allows imaging of samples with high spatial resolution and a wide field of view. However, conventional microscopy methods are limited…

Optics · Physics 2023-03-10 Yichang Shou , Jiawei Liu , Hailu Luo

The fast-growing field of soft matter research requires increasingly sophisticated tools for experimental studies. One of the oldest and most widely used tools to study soft matter systems is optical microscopy. Recent advances in optical…

Soft Condensed Matter · Physics 2011-08-17 Taewoo Lee , Bohdan Senyuk , Rahul P. Trivedi , Ivan I. Smalyukh

Metasurfaces have revolutionized the design concepts for opticalcomponents, fostering an excitingfield offlat optics. Thanks to theflat and ultrathinnature, metasurfaces possess unique advantages over conventional optical components,such as…

Optics · Physics 2021-05-03 Jianxiong Li , Ping Yu , Shuang Zhang , Na Liu

Gradient-based inverse design in photonics has already achieved remarkable results in designing small-footprint, high-performance optical devices. The adjoint variable method, which allows for the efficient computation of gradients, has…