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The availability of genomic data has grown exponentially in the last decade, mainly due to the development of new sequencing technologies. Based on the interactions between genes (and gene products) extracted from the increasing genomic…

Machine Learning · Computer Science 2022-07-14 Miguel Romero , Felipe Kenji Nakano , Jorge Finke , Camilo Rocha , Celine Vens

One of the major challenges arising from single-cell transcriptomics experiments is the question of how to annotate the associated single-cell transcriptomic profiles. Because of the large size and the high dimensionality of the data,…

Genomics · Quantitative Biology 2024-09-11 Malek Senoussi , Thierry Artières , Paul Villoutreix

Clustering genotypes based upon their phenotypic characteristics is used to obtain diverse sets of parents that are useful in their breeding programs. The Hierarchical Clustering (HC) algorithm is the current standard in clustering of…

Machine Learning · Computer Science 2020-09-22 Aditya A. Shastri , Kapil Ahuja , Milind B. Ratnaparkhe , Yann Busnel

Node classification is the task of inferring or predicting missing node attributes from information available for other nodes in a network. This paper presents a general prediction model to hierarchical multi-label classification (HMC),…

Machine Learning · Computer Science 2022-03-24 Miguel Romero , Jorge Finke , Camilo Rocha

Hierarchical multi-label classification (HMC) is a challenging classification task extending standard multi-label classification problems by imposing a hierarchy constraint on the classes. In this paper, we propose C-HMCNN(h), a novel…

Machine Learning · Computer Science 2021-11-29 Eleonora Giunchiglia , Thomas Lukasiewicz

The problem of multilabel classification when the labels are related through a hierarchical categorization scheme occurs in many application domains such as computational biology. For example, this problem arises naturally when trying to…

Machine Learning · Computer Science 2012-05-14 Sara Mostafavi , Quaid Morris

High-dimensional clustering analysis is a challenging problem in statistics and machine learning, with broad applications such as the analysis of microarray data and RNA-seq data. In this paper, we propose a new clustering procedure called…

Methodology · Statistics 2022-10-31 Tianqi Liu , Yu Lu , Biqing Zhu , Hongyu Zhao

Hierarchical multi-granularity classification (HMC) assigns hierarchical multi-granularity labels to each object and focuses on encoding the label hierarchy, e.g., ["Albatross", "Laysan Albatross"] from coarse-to-fine levels. However, the…

Computer Vision and Pattern Recognition · Computer Science 2022-01-12 Jingzhou Chen , Peng Wang , Jian Liu , Yuntao Qian

Spectral clustering is one of the most popular clustering methods. However, the high computational cost due to the involved eigen-decomposition procedure can immediately hinder its applications in large-scale tasks. In this paper we use…

Machine Learning · Computer Science 2023-01-24 Yongyu Wang

Multi-label classification (MC) is a standard machine learning problem in which a data point can be associated with a set of classes. A more challenging scenario is given by hierarchical multi-label classification (HMC) problems, in which…

Machine Learning · Computer Science 2022-10-05 Eleonora Giunchiglia , Thomas Lukasiewicz

We propose an effective method to improve Protein Function Prediction (PFP) utilizing hierarchical features of Gene Ontology (GO) terms. Our method consists of a language model for encoding the protein sequence and a Graph Convolutional…

Artificial Intelligence · Computer Science 2021-12-07 Kyudam Choi , Yurim Lee , Cheongwon Kim , Minsung Yoon

Spectral clustering is a celebrated algorithm that partitions objects based on pairwise similarity information. While this approach has been successfully applied to a variety of domains, it comes with limitations. The reason is that there…

Statistics Theory · Mathematics 2018-05-24 Kwangjun Ahn , Kangwook Lee , Changho Suh

Annotations are necessary to develop computer vision algorithms for histopathology, but dense annotations at a high resolution are often time-consuming to make. Deep learning models for segmentation are a way to alleviate the process, but…

Computer Vision and Pattern Recognition · Computer Science 2022-11-15 Eduard Chelebian , Francesco Ciompi , Carolina Wählby

Deep clustering as an important branch of unsupervised representation learning focuses on embedding semantically similar samples into the identical feature space. This core demand inspires the exploration of contrastive learning and…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Haifeng Xia , Hai Huang , Zhengming Ding

Hierarchical classification is a crucial task in many applications, where objects are organized into multiple levels of categories. However, conventional classification approaches often neglect inherent inter-class relationships at…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Julius Ott , Nastassia Vysotskaya , Huawei Sun , Lorenzo Servadei , Robert Wille

As research interests in medical image analysis become increasingly fine-grained, the cost for extensive annotation also rises. One feasible way to reduce the cost is to annotate with coarse-grained superclass labels while using limited…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Linrui Dai , Wenhui Lei , Xiaofan Zhang

Cluster analysis has proved to be an invaluable tool for the exploratory and unsupervised analysis of high dimensional datasets. Among methods for clustering, hierarchical approaches have enjoyed substantial popularity in genomics and other…

Methodology · Statistics 2014-11-20 Patrick K. Kimes , Yufeng Liu , D. Neil Hayes , J. S. Marron

Clustering data objects into homogeneous groups is one of the most important tasks in data mining. Spectral clustering is arguably one of the most important algorithms for clustering, as it is appealing for its theoretical soundness and is…

Machine Learning · Statistics 2024-03-12 Dylan Soemitro , Jeova Farias Sales Rocha Neto

Clustering aims to group unlabelled samples based on their similarities. It has become a significant tool for the analysis of high-dimensional data. However, most of the clustering methods merely generate pseudo labels and thus are unable…

Artificial Intelligence · Computer Science 2023-06-21 Tianyi Huang , Shenghui Cheng , Stan Z. Li , Zhengjun Zhang

This study introduces a novel hierarchical divisive clustering approach with stochastic splitting functions (SSFs) to enhance classification performance in multi-class datasets through hierarchical classification (HC). The method has the…

Machine Learning · Computer Science 2023-09-22 Celal Alagoz
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