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Microarrays are made it possible to simultaneously monitor the expression profiles of thousands of genes under various experimental conditions. Identification of co-expressed genes and coherent patterns is the central goal in microarray or…

Computational Engineering, Finance, and Science · Computer Science 2013-07-15 T. Chandrasekhar , K. Thangavel , E. Elayaraja , E. N. Sathishkumar

Motivation: Genomic data analyses such as Genome-Wide Association Studies (GWAS) or Hi-C studies are often faced with the problem of partitioning chromosomes into successive regions based on a similarity matrix of high-resolution,…

Statistics Theory · Mathematics 2019-02-06 Christophe Ambroise , Alia Dehman , Pierre Neuvial , Guillem Rigaill , Nathalie Vialaneix

We propose a hierarchical graph neural network (GNN) model that learns how to cluster a set of images into an unknown number of identities using a training set of images annotated with labels belonging to a disjoint set of identities. Our…

Computer Vision and Pattern Recognition · Computer Science 2021-07-20 Yifan Xing , Tong He , Tianjun Xiao , Yongxin Wang , Yuanjun Xiong , Wei Xia , David Wipf , Zheng Zhang , Stefano Soatto

Gene mutation prediction in hepatocellular carcinoma (HCC) is of great diagnostic and prognostic value for personalized treatments and precision medicine. In this paper, we tackle this problem with multi-instance multi-label learning to…

Machine Learning · Computer Science 2022-03-24 Kaixin Xu , Ziyuan Zhao , Jiapan Gu , Zeng Zeng , Chan Wan Ying , Lim Kheng Choon , Thng Choon Hua , Pierce KH Chow

Hierarchical Extreme Multi-Label Classification poses greater difficulties compared to traditional multi-label classification because of the intricate hierarchical connections of labels within a domain-specific taxonomy and the substantial…

Machine Learning · Computer Science 2025-05-08 Linqing Chen , Weilei Wang , Wentao Wu , Hanmeng Zhong

Tensor clustering, which seeks to extract underlying cluster structures from noisy tensor observations, has gained increasing attention. One extensively studied model for tensor clustering is the tensor block model, which postulates the…

Statistics Theory · Mathematics 2023-11-07 Yuchen Zhou , Yuxin Chen

Collecting large annotated datasets in Remote Sensing is often expensive and thus can become a major obstacle for training advanced machine learning models. Common techniques of addressing this issue, based on the underlying idea of…

Computer Vision and Pattern Recognition · Computer Science 2021-08-18 Rahul Ghosh , Xiaowei Jia , Chenxi Lin , Zhenong Jin , Vipin Kumar

High-density DNA arrays, used to monitor gene expression at a genomic scale, have produced vast amounts of information which require the development of efficient computational methods to analyze them. The important first step is to extract…

Biological Physics · Physics 2009-10-31 G. Getz , E. Levine , E. Domany , M. Q. Zhang

Several modern genomic technologies, such as DNA-Methylation arrays, measure spatially registered probes that number in the hundreds of thousands across multiplechromosomes. The measured probes are by themselves less interesting…

Applications · Statistics 2016-11-16 John Nagorski , Genevera I. Allen

Annotation cost is a bottleneck for collecting massive data in mammography, especially for training deep neural networks. In this paper, we study the use of heterogeneous levels of annotation granularity to improve predictive performances.…

Image and Video Processing · Electrical Eng. & Systems 2019-09-13 Thi-Lam-Thuy Le , Nicolas Thome , Sylvain Bernard , Vincent Bismuth , Fanny Patoureaux

Hyperspectral image classification (HIC) is an important but challenging task, and a problem that limits the algorithmic development in this field is that the ground truths of hyperspectral images (HSIs) are extremely hard to obtain.…

Computer Vision and Pattern Recognition · Computer Science 2020-12-22 Hao Zeng , Qingjie Liu , Mingming Zhang , Xiaoqing Han , Yunhong Wang

Clustering is a difficult and widely-studied data mining task, with many varieties of clustering algorithms proposed in the literature. Nearly all algorithms use a similarity measure such as a distance metric (e.g. Euclidean distance) to…

Neural and Evolutionary Computing · Computer Science 2019-10-24 Andrew Lensen , Bing Xue , Mengjie Zhang

The hidden Markov model (HMM) is a widely-used generative model that copes with sequential data, assuming that each observation is conditioned on the state of a hidden Markov chain. In this paper, we derive a novel algorithm to cluster HMMs…

Machine Learning · Computer Science 2012-10-26 Emanuele Coviello , Antoni B. Chan , Gert R. G. Lanckriet

Modern clustering approaches often trade interpretability for performance, particularly in deep learning-based methods. We present Generative Kernel Spectral Clustering (GenKSC), a novel model combining kernel spectral clustering with…

Machine Learning · Computer Science 2025-04-25 David Winant , Sonny Achten , Johan A. K. Suykens

Getting a robust time-series clustering with best choice of distance measure and appropriate representation is always a challenge. We propose a novel mechanism to identify the clusters combining learned compact representation of…

Machine Learning · Computer Science 2021-01-12 Soma Bandyopadhyay , Anish Datta , Arpan Pal

The problem of Hybrid Linear Modeling (HLM) is to model and segment data using a mixture of affine subspaces. Different strategies have been proposed to solve this problem, however, rigorous analysis justifying their performance is missing.…

Machine Learning · Statistics 2009-08-27 Guangliang Chen , Gilad Lerman

Characterizing genes with semantic information is an important process regarding the description of gene products. In spite that complete genomes of many organisms have been already sequenced, the biological functions of all of their genes…

Artificial Intelligence · Computer Science 2016-08-15 Guillermo Leale , Ariel Bayá , Diego Milone , Pablo Granitto , Georgina Stegmayer

To understand complex biological systems, the research community has produced huge corpus of gene expression data. A large number of clustering approaches have been proposed for the analysis of gene expression data. However, extracting…

Computational Engineering, Finance, and Science · Computer Science 2010-03-28 Swathi. H

Spectral clustering algorithms typically require a priori selection of input parameters such as the number of clusters, a scaling parameter for the affinity measure, or ranges of these values for parameter tuning. Despite efforts for…

Machine Learning · Computer Science 2019-03-20 Milad Afzalan , Farrokh Jazizadeh

Hierarchical clustering is one of the most powerful solutions to the problem of clustering, on the grounds that it performs a multi scale organization of the data. In recent years, research on hierarchical clustering methods has attracted…

Machine Learning · Computer Science 2019-08-02 Antonia Korba