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Multiple interlinked positive feedback loops shape the stimulus responses of various biochemical systems, such as the cell cycle or intracellular calcium release. Recent studies with simplified models have identified two advantages of…

Molecular Networks · Quantitative Biology 2012-08-31 Paul Smolen , Douglas A. Baxter , John H. Byrne

While spiking neural networks (SNNs) provide a biologically inspired and energy-efficient computational framework, their robustness and the dynamic advantages inherent to biological neurons remain significantly underutilized owing to…

Neural and Evolutionary Computing · Computer Science 2025-09-04 Qianyi Bai , Haiteng Wang , Qiang Yu

Living substrates are capable for nontrivial mappings of electrical signals due to the substrate nonlinear electrical characteristics. This property can be used to realise Boolean functions. Input logical values are represented by amplitude…

Emerging Technologies · Computer Science 2021-08-12 Nic Roberts , Andrew Adamatzky

The escalating energy demands of artificial intelligence pose a critical challenge to conventional computing. Leveraging the efficiency of event-driven, in-memory neuromorphic architectures into the superconducting circuits with ultra-high…

Emerging Technologies · Computer Science 2026-04-07 Muen Wang , Shucheng Yang , Yuxiang Lin , Yuntian Gao , Xue Zhang , Xiaoping Gao , Minghui Niu , Huanli Liu , Yikang Wan , Wei Peng , Jie Ren

An analog synapse circuit based on ferroelectric-metal field-effect transistors is proposed, that offers 6-bit weight precision. The circuit is comprised of volatile least significant bits (LSBs) used solely during training, and…

Emerging Technologies · Computer Science 2020-04-03 Arman Kazemi , Ramin Rajaei , Kai Ni , Suman Datta , Michael Niemier , X. Sharon Hu

Synaptic memory is considered to be the main element responsible for learning and cognition in humans. Although traditionally non-volatile long-term plasticity changes have been implemented in nanoelectronic synapses for neuromorphic…

Emerging Technologies · Computer Science 2017-12-20 Abhronil Sengupta , Kaushik Roy

Synaptic plasticity is the capacity of a preexisting connection between two neurons to change in strength as a function of neural activity. Because synaptic plasticity is the major candidate mechanism for learning and memory, the…

Neurons and Cognition · Quantitative Biology 2015-05-05 Maurizio De Pittà , Nicolas Brunel , Andrea Volterra

For the successful implementation of organic electrochemical transistors in neuromorphic computing, bioelectronics, and real-time sensing applications it is essential to understand the factors that influence device switching times. Here we…

Applied Physics · Physics 2024-10-10 Juan Bisquert , Nir Tessler

Neuromorphic electronics and spiking neural networks (SNNs) offer energy-efficient data processing, essential for real-time and edge-computing applications. In particular, interfacing and processing biological signals require devices that…

Applied Physics · Physics 2026-04-16 Nikita Prudnikov , Yeohoon Yoon , Hans Kleemann

Complementary metal oxide semiconductor (CMOS) devices display volatile characteristics, and are not well suited for analog applications such as neuromorphic computing. Spintronic devices, on the other hand, exhibit both non-volatile and…

Spike-Timing Dependent Plasticity (STDP) is believed to play an important role in learning and the formation of computational function in the brain. The classical model of STDP which considers the timing between pairs of pre-synaptic and…

Neural and Evolutionary Computing · Computer Science 2013-03-21 Mostafa Rahimi Azghadi , Said Al-Sarawi , Nicolangelo Iannella , Derek Abbott

Memristors have demonstrated immense potential as building blocks in future adaptive neuromorphic architectures. Recently, there has been focus on emulating specific synaptic functions of the mammalian nervous system by either tailoring the…

Disordered Systems and Neural Networks · Physics 2018-04-19 Taimur Ahmed , Sumeet Walia , Edwin Mayes , Rajesh Ramanathan , Vipul Bansal , Madhu Bhaskaran , Sharath Sriram , Omid Kavehei

The study of synchronization in biological systems is essential for the understanding of the rhythmic phenomena of living organisms at both molecular and cellular levels. In this paper, by using simple dynamical systems theory, we present a…

Molecular Networks · Quantitative Biology 2007-05-23 Chunguang Li , Luonan Chen , Kazuyuki Aihara

Circuits using superconducting single-photon detectors and Josephson junctions to perform signal reception, synaptic weighting, and integration are investigated. The circuits convert photon-detection events into flux quanta, the number of…

Replicating the computational functionalities and performances of the brain remains one of the biggest challenges for the future of information and communication technologies. Such an ambitious goal requires research efforts from the…

Biological Physics · Physics 2015-05-20 Selina La Barbera , Dominique Vuillaume , Fabien Alibart

Memories are stored, retained, and recollected through complex, coupled processes operating on multiple timescales. To understand the computational principles behind these intricate networks of interactions we construct a broad class of…

Neurons and Cognition · Quantitative Biology 2015-07-29 Marcus K. Benna , Stefano Fusi

Neuromorphic devices represent an attempt to mimic aspects of the brain's architecture and dynamics with the aim of replicating its hallmark functional capabilities in terms of computational power, robust learning and energy efficiency. We…

The synapse is a key element of neuromorphic computing in terms of efficiency and accuracy. In this paper, an optimized current-controlled memristive synapse circuit is proposed. Our proposed synapse demonstrates reliability in the face of…

Emerging Technologies · Computer Science 2023-09-11 Hritom Das , Rocco D. Febbo , Charlie P. Rizzo , Nishith N. Chakraborty , James S. Plank , Garrett S. Rose

Memristors have been widely studied as artificial synapses in neuromorphic circuits, due to their functional similarity with biological synapses, low operating power, and high integration density. In this work, a memristive synapse,…

Emerging Technologies · Computer Science 2023-08-29 Y. Liu , D. Wang , Z. Dong , H. Xie , W. Zhao

Colloids submitted to electrical stimuli exhibit a reconfiguration that could be used to store information and, potentially, compute. We investigated learnign, memorization, and time and stimulation's voltage dependence of conductive…

Emerging Technologies · Computer Science 2022-11-02 Noushin Raeisi Kheirabadi , Alessandro Chioleriob , Neil Phillipsa , Andrew Adamatzky