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Associative learning is one of the key mechanisms displayed by living organisms in order to adapt to their changing environments. It was early recognized to be a general trait of complex multicellular organisms but also found in "simpler"…

Cell Behavior · Quantitative Biology 2017-01-24 Javier Macia , Blai Vidiella , Ricard Sole

Understanding how biological neural networks carry out learning using spike-based local plasticity mechanisms can lead to the development of powerful, energy-efficient, and adaptive neuromorphic processing systems. A large number of…

Neural and Evolutionary Computing · Computer Science 2022-11-08 Lyes Khacef , Philipp Klein , Matteo Cartiglia , Arianna Rubino , Giacomo Indiveri , Elisabetta Chicca

Optical communication achieves high fanout and short delay advantageous for information integration in neural systems. Superconducting detectors enable signaling with single photons for maximal energy efficiency. We present designs of…

Neural and Evolutionary Computing · Computer Science 2018-11-14 Jeffrey M. Shainline , Sonia M. Buckley , Adam N. McCaughan , Jeff Chiles , Richard P. Mirin , Sae Woo Nam

Many biological systems can sense periodical variations in a stimulus input and produce well-timed, anticipatory responses after the input is removed. Such systems show memory effects for retaining timing information in the stimulus and…

Neurons and Cognition · Quantitative Biology 2015-09-09 Ying-Jen Yang , Chun-Chung Chen , Pik-Yin Lai , C. K. Chan

With conventional silicon-based computing approaching its physical and efficiency limits, biocomputing emerges as a promising alternative. This approach utilises biomaterials such as DNA and neurons as an interesting alternative to data…

Emerging Technologies · Computer Science 2024-08-15 Giulio Basso , Reinhold Scherer , Michael Taynnan Barros

Energy consumption remains the main limiting factors in many IoT applications. In particular, micro-controllers consume far too much power. In order to overcome this problem, new circuit designs have been proposed and the use of spiking…

Neural and Evolutionary Computing · Computer Science 2023-11-20 Guillaume Marthe , Claire Goursaud , Romain Cazé , Laurent Clavier

Several analog and digital brain-inspired electronic systems have been recently proposed as dedicated solutions for fast simulations of spiking neural networks. While these architectures are useful for exploring the computational properties…

Emerging Technologies · Computer Science 2017-11-08 Elisabetta Chicca , Fabio Stefanini , Chiara Bartolozzi , Giacomo Indiveri

Learning and memory relies on synapses changing their strengths in response to neural activity. However there is a substantial gap between the timescales of neural electrical dynamics (1-100 ms) and organism behaviour during learning…

Neurons and Cognition · Quantitative Biology 2023-08-08 Cian O'Donnell

We demonstrate an electrolyte-gated hybrid nanoparticle/organic synapstor (synapse-transistor, termed EGOS) that exhibits short-term plasticity as biological synapses. The response of EGOS makes it suitable to be interfaced with neurons:…

In digital circuits, a Flip-Flop (FF) is a circuit element that has two stable states which can be used to store and remember state information. The state of the circuit can be changed by applying signals to the control input. FFs are the…

Quantum Physics · Physics 2017-11-29 Dawit Hiluf , Yonatan Dubi

Humans and animals learn throughout life. Such continual learning is crucial for intelligence. In this chapter, we examine the pivotal role plasticity mechanisms with complex internal synaptic dynamics could play in enabling this ability in…

Neurons and Cognition · Quantitative Biology 2024-10-21 Friedemann Zenke , Axel Laborieux

With memory encoding reliant on persistent changes in the properties of synapses, a key question is how can memories be maintained from days to months or a lifetime given molecular turnover? It is likely that positive feedback loops are…

Neurons and Cognition · Quantitative Biology 2019-04-18 Paul Smolen , Douglas A. Baxter , John H. Byrne

Sophisticated machine learning struggles to transition onto battery-operated devices due to the high-power consumption of neural networks. Researchers have turned to neuromorphic engineering, inspired by biological neural networks, for more…

Neural and Evolutionary Computing · Computer Science 2023-11-23 Daniel John Mannion

A large effort is devoted to the research of new computing paradigms associated to innovative nanotechnologies that should complement and/or propose alternative solutions to the classical Von Neumann/CMOS association. Among various…

Mesoscale and Nanoscale Physics · Physics 2012-02-09 F. Alibart , S. Pleutin , O. Bichler , C. Gamrat , T. Serrano-Gotarredona , B. Linares-Barranco , D. Vuillaume

Electronic circuits are useful tools for studying potential dynamical behaviors of synthetic genetic networks. The circuit models are complementary to numerical simulations of the networks, especially providing a framework for verification…

Biological Physics · Physics 2017-07-07 Edward H. Hellen , Syamal K. Dana

Artificial synapse is a key element of future brain-inspired neuromorphic computing systems implemented in hardware. This work presents a graphene synaptic transistor based on all-technology-compatible materials that exhibits highly tunable…

The co-location of memory and processing is a core principle of neuromorphic computing. A local memory device for synaptic weight storage has long been recognized as an enabling element for large-scale, high-performance neuromorphic…

Applied Physics · Physics 2023-11-13 Bryce A. Primavera , Saeed Khan , Richard P. Mirin , Sae Woo Nam , Jeffrey M. Shainline

The interplay between excitatory and inhibitory neurons imparts rich functions of the brain. To understand the underlying synaptic mechanisms, a fundamental approach is to study the dynamics of excitatory and inhibitory conductances of each…

Neurons and Cognition · Quantitative Biology 2017-10-17 Songting Li , Nan Liu , Xiaohui Zhang , Douglas Zhou , David Cai

Neuro-inspired computing architectures are one of the leading candidates to solve complex, large-scale associative learning problems. The two key building blocks for neuromorphic computing are the synapse and the neuron, which form the…

Applied Physics · Physics 2019-01-16 Boyang Zhao , Jayakanth Ravichandran

The design of neural hardware is informed by the prominence of differentiated processing and information integration in cognitive systems. The central role of communication leads to the principal assumption of the hardware platform: signals…

Neural and Evolutionary Computing · Computer Science 2018-05-28 Jeffrey M. Shainline , Sonia M. Buckley , Adam N. McCaughan , Jeff Chiles , Richard P. Mirin , Sae Woo Nam