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Cryo-electron microscopy (cryo-EM) has emerged as a powerful technique for resolving the three-dimensional structures of macromolecules. A key challenge in cryo-EM is characterizing continuous heterogeneity, where molecules adopt a…

Machine Learning · Statistics 2026-02-20 Roey Yadgar , Roy R. Lederman , Yoel Shkolnisky

Electron cryo-tomography (cryo-ET) enables 3D imaging of complex, radiation-sensitive structures with molecular detail. However, image contrast from the interference of scattered electrons is nonlinear with atomic density and multiple…

Electron and scanning probe microscopy produce vast amounts of data in the form of images or hyperspectral data, such as EELS or 4D STEM, that contain information on a wide range of structural, physical, and chemical properties of…

Machine Learning · Computer Science 2023-06-09 Arpan Biswas , Maxim Ziatdinov , Sergei V. Kalinin

We consider the task of learning a classifier for semantic segmentation using weak supervision in the form of image labels which specify the object classes present in the image. Our method uses deep convolutional neural networks (CNNs) and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-07 Qinbin Hou , Puneet Kumar Dokania , Daniela Massiceti , Yunchao Wei , Ming-Ming Cheng , Philip Torr

To assist researchers to identify Environmental Microorganisms (EMs) effectively, a Multiscale CNN-CRF (MSCC) framework for the EM image segmentation is proposed in this paper. There are two parts in this framework: The first is a novel…

Computer Vision and Pattern Recognition · Computer Science 2021-02-25 Jinghua Zhang , Chen Li , Frank Kulwa , Xin Zhao , Changhao Sun , Zihan Li , Tao Jiang , Hong Li , Shouliang Qi

Scanning transmission electron microscopy (STEM) is now the primary tool for exploring functional materials on the atomic level. Often, features of interest are highly localized in specific regions in the material, such as ferroelectric…

Materials Science · Physics 2021-08-11 Nicole Creange , Ondrej Dyck , Rama K. Vasudevan , Maxim Ziatdinov , Sergei V. Kalinin

Capacitively coupled plasmas (CCP) comprise one of the main tool in active use in the plasma processing industry. However, increasing the driving frequency and electrode size is limited by the emergence of plasma radial nonuniformity…

Plasma Physics · Physics 2023-03-03 D. Eremin , E. Kemaneci , M. Matsukuma , I. Kaganovich , T. Mussenbrock , R. P. Brinkmann

At a single atom thick, it is challenging to distinguish graphene from its substrate using conventional techniques. In this paper we show that friction force microscopy (FFM) is a simple and quick technique for identifying graphene on a…

Materials Science · Physics 2015-06-12 Alexander J. Marsden , Mick Phillips , Neil R. Wilson

Cryo-electron microscopy (cryo-EM) enables single-particle analysis of biological macromolecules under strict low-dose imaging conditions, but the resulting micrographs often exhibit extremely low signal-to-noise ratios and weak particle…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Xiaoqi Wu , Xueying Zhan , Wen Li , Junhao Wu , Xin Huang , Min Xu

We used low-temperature scanning electron microscopy (LTSEM) for imaging quantized magnetic flux (vortices) in direct current (dc) superconducting quantum interference devices (SQUIDs) with approximately 1 micron spatial resolution at…

Superconductivity · Physics 2009-11-07 R. Straub , S. Keil , R. Kleiner , D. Koelle

Characterisation of rare microstructural features in scanning electron microscopy (SEM) requires imaging large areas at high resolution. This leads to prohibitively long acquisition times. We present an open-source Python framework that…

Sparsity has been widely recognized as crucial for efficient optimization in graph-based SLAM. Because the sparsity and structure of the SLAM graph reflect the set of incorporated measurements, many methods for sparsification have been…

Robotics · Computer Science 2018-03-06 Kristoffer M. Frey , Ted J. Steiner , Jonathan P. How

In the present article we investigate optical near fields in semiconductor lasers. We perform finite element simulations for two different laser types, namely a super large optical waveguide (SLOW) laser, which is an edge emitter, and a…

Optics · Physics 2010-11-30 J. Pomplun , S. Burger , F. Schmidt , A. Schliwa , D. Bimberg , A. Pietrzak , H. Wenzel , G. Erbert

Kelvin probe force microscopy (KPFM) is a powerful tool for studying contact electrification at the nanoscale, but converting KPFM voltage maps to charge density maps is non-trivial due to long-range forces and complex system geometry. Here…

Soft Condensed Matter · Physics 2022-11-30 Felix Pertl , Juan Carlos Sobarzo , Lubuna Shafeek , Tobias Cramer , Scott Waitukaitis

Single particle cryo-electron microscopy has become a critical tool in structural biology over the last decade, able to achieve atomic scale resolution in three dimensional models from hundreds of thousands of (noisy) two-dimensional…

Numerical Analysis · Mathematics 2023-07-19 Aaditya V. Rangan , Leslie Greengard

Information about microscopic objects with features smaller than the diffraction limit is almost entirely lost in a far-field diffraction image but could be partly recovered with data completition techniques. Any such approach critically…

Optics · Physics 2020-11-17 Maria Bancerek , Krzysztof M. Czajkowski , Rafal Kotynski

The success and generalisation of deep learning algorithms heavily depend on learning good feature representations. In medical imaging this entails representing anatomical information, as well as properties related to the specific imaging…

Computer Vision and Pattern Recognition · Computer Science 2020-04-21 Agisilaos Chartsias , Thomas Joyce , Giorgos Papanastasiou , Scott Semple , Michelle Williams , David Newby , Rohan Dharmakumar , Sotirios A. Tsaftaris

Machine-learning algorithms have shown outstanding image recognition or classification performance for computer vision applications. However, the compute and energy requirement for implementing such classifier models for large-scale…

Computer Vision and Pattern Recognition · Computer Science 2017-03-09 Priyadarshini Panda , Aayush Ankit , Parami Wijesinghe , Kaushik Roy

The surface magnetization of Fe$_3$GeTe$_2$ was examined by low-energy electron microscopy (LEEM) using an off-normal incidence electron beam. We found that the 180$^o$ domain walls are of Bloch type. Temperature-dependent LEEM measurements…

Rydberg atoms, which possess exceptionally large electric dipole moments, offer a promising route for electric field sensing as well as metrology traceable to the International System of Units (SI); however, current research predominantly…

Quantum Physics · Physics 2026-04-20 Tianyu Zhou , Haipeng Xie , Xin Wang