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Drug discovery and development is a complex and costly process. Machine learning approaches are being investigated to help improve the effectiveness and speed of multiple stages of the drug discovery pipeline. Of these, those that use…

Artificial Intelligence · Computer Science 2022-09-27 Stephen Bonner , Ian P Barrett , Cheng Ye , Rowan Swiers , Ola Engkvist , Andreas Bender , Charles Tapley Hoyt , William L Hamilton

The exponential growth of neuroscience literature presents a significant challenge for researchers seeking to efficiently access and utilize relevant information. To address this issue, we introduce the Brain Knowledge Engine (BrainKnow),…

Digital Libraries · Computer Science 2024-06-07 Cunqing Huangfu , Kang Sun , Yi Zeng , Yuwei Wang , Dongsheng Wang , Zizhe Ruan

Traditional methods of linking large language models (LLMs) to knowledge bases via the semantic similarity search often fall short of capturing complex relational dynamics. To address these limitations, we introduce AutoKG, a lightweight…

Computation and Language · Computer Science 2023-11-28 Bohan Chen , Andrea L. Bertozzi

Multi-omics data offer unprecedented insights into complex biological systems, yet their high dimensionality, sparsity, and intricate interactions pose significant analytical challenges. Network-based approaches have advanced multi-omics…

We are developing infrastructure to support researchers in mapping data related to the peripheral nervous system and other physiological systems, with an emphasis on their relevance to the organs under investigation. The nervous system, a…

Artificial Intelligence · Computer Science 2025-09-22 Natallia Kokash , Bernard de Bono , Tom Gillespie

Equipping machines with comprehensive knowledge of the world's entities and their relationships has been a long-standing goal of AI. Over the last decade, large-scale knowledge bases, also known as knowledge graphs, have been automatically…

Artificial Intelligence · Computer Science 2021-12-07 Gerhard Weikum , Luna Dong , Simon Razniewski , Fabian Suchanek

With the rapid development of biomedical software and hardware, a large amount of relational data interlinking genes, proteins, chemical components, drugs, diseases, and symptoms has been collected for modern biomedical research. Many…

Artificial Intelligence · Computer Science 2021-01-21 Yankai Chen , Yaozu Wu , Shicheng Ma , Irwin King

The exponential growth in scholarly publications necessitates advanced tools for efficient article retrieval, especially in interdisciplinary fields where diverse terminologies are used to describe similar research. Traditional…

Knowledge graphs and structural causal models have each proven valuable for organizing biomedical knowledge and estimating causal effects, but remain largely disconnected: knowledge graphs encode qualitative relationships focusing on facts…

Artificial Intelligence · Computer Science 2025-05-13 Sumyyah Toonsi , Paul Schofield , Robert Hoehndorf

This paper introduces MatKG, a novel graph database of key concepts in material science spanning the traditional material-structure-property-processing paradigm. MatKG is autonomously generated through transformer-based, large language…

Materials Science · Physics 2022-11-01 Vineeth Venugopal , Sumit Pai , Elsa Olivetti

We present an interactive visualization of the Cell Map for AI Talent Knowledge Graph (CM4AI TKG), a detailed semantic space comprising approximately 28,000 experts and 1,000 datasets focused on the biomedical field. Our tool leverages…

Social and Information Networks · Computer Science 2025-01-20 Jiawei Xu , Zhandos Sembay , Swathi Thaker , Pamela Payne-Foster , Jake Yue Chen , Ying Ding

A scientific paper can be divided into two major constructs which are Metadata and Full-body text. Metadata provides a brief overview of the paper while the Full-body text contains key-insights that can be valuable to fellow researchers. To…

Digital Libraries · Computer Science 2023-08-28 Azanzi Jiomekong , Sanju Tiwari

X-ray medical report generation is one of the important applications of artificial intelligence in healthcare. With the support of large foundation models, the quality of medical report generation has significantly improved. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Futian Wang , Yuhan Qiao , Xiao Wang , Fuling Wang , Yuxiang Zhang , Dengdi Sun

Recent advancements in artificial intelligence have significantly improved the automatic generation of radiology reports. However, existing evaluation methods fail to reveal the models' understanding of radiological images and their…

Artificial Intelligence · Computer Science 2024-08-27 Xiaoman Zhang , Julián N. Acosta , Hong-Yu Zhou , Pranav Rajpurkar

Medical dialogue generation is an important yet challenging task. Most previous works rely on the attention mechanism and large-scale pretrained language models. However, these methods often fail to acquire pivotal information from the long…

Artificial Intelligence · Computer Science 2022-06-20 Yu Zhao , Yunxin Li , Yuxiang Wu , Baotian Hu , Qingcai Chen , Xiaolong Wang , Yuxin Ding , Min Zhang

Personalized oncology aims to tailor treatment strategies to the unique molecular and clinical profiles of individual patients, moving beyond the traditional paradigm of treating the disease not the patient. Achieving this vision requires…

Laboratory workflows in pharmaceutical and biomedical research encode substantial tacit knowledge -- expert judgment about failure conditions, decision branching logic, and contextual dependencies -- that remains inaccessible to protocol…

Modern computer systems often rely on syslog, a simple, universal protocol that records every critical event across heterogeneous infrastructure. However, healthcare's rapidly growing clinical AI stack has no equivalent. As hospitals rush…

Intelligent systems designed using machine learning algorithms require a large number of labeled data. Background knowledge provides complementary, real world factual information that can augment the limited labeled data to train a machine…

Artificial Intelligence · Computer Science 2020-05-12 Shreyansh Bhatt , Amit Sheth , Valerie Shalin , Jinjin Zhao

Large Language Models (LLMs) have shown remarkable progress in medical question answering (QA), yet their effectiveness remains predominantly limited to English due to imbalanced multilingual training data and scarce medical resources for…