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We present alphaPDE, a new multivariate analysis technique for parameter estimation. The method is based on a direct construction of joint probability densities of known variables and the parameters to be estimated. We show how posterior…

Data Analysis, Statistics and Probability · Physics 2009-11-07 B. Knuteson , H. Miettinen , L. Holmstrom

Signal peptide (SP) is a short peptide located in the N-terminus of proteins. It is essential to target and transfer transmembrane and secreted proteins to correct positions. Compared with traditional experimental methods to identify signal…

Artificial Intelligence · Computer Science 2023-12-15 Junbo Shen , Qinze Yu , Shenyang Chen , Qingxiong Tan , Jingcheng Li , Yu Li

Learning effective protein representations is critical in a variety of tasks in biology such as predicting protein functions. Recent sequence representation learning methods based on Protein Language Models (PLMs) excel in sequence-based…

Quantitative Methods · Quantitative Biology 2023-10-19 Zuobai Zhang , Chuanrui Wang , Minghao Xu , Vijil Chenthamarakshan , Aurélie Lozano , Payel Das , Jian Tang

The denoising model has been proven a powerful generative model but has little exploration of discriminative tasks. Representation learning is important in discriminative tasks, which is defined as "learning representations (or features) of…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Zhengrui Xu , Guan'an Wang , Xiaowen Huang , Jitao Sang

Protein representation learning methods have shown great potential to yield useful representation for many downstream tasks, especially on protein classification. Moreover, a few recent studies have shown great promise in addressing…

Machine Learning · Computer Science 2023-04-11 Can Chen , Jingbo Zhou , Fan Wang , Xue Liu , Dejing Dou

Establishing robust and accurate correspondences is a fundamental backbone to many computer vision algorithms. While recent learning-based feature matching methods have shown promising results in providing robust correspondences under…

Computer Vision and Pattern Recognition · Computer Science 2020-04-06 Hugo Germain , Guillaume Bourmaud , Vincent Lepetit

This paper proposes a deep denoising auto-encoder technique to extract better acoustic features for speech synthesis. The technique allows us to automatically extract low-dimensional features from high dimensional spectral features in a…

Sound · Computer Science 2015-06-18 Zhenzhou Wu , Shinji Takaki , Junichi Yamagishi

A promising technique of discovering disease biomarkers is to measure the relative protein abundance in multiple biofluid samples through liquid chromatography with tandem mass spectrometry (LC-MS/MS) based quantitative proteomics. The key…

Computer Vision and Pattern Recognition · Computer Science 2020-09-16 Fatema Tuz Zohora , M Ziaur Rahman , Ngoc Hieu Tran , Lei Xin , Baozhen Shan , Ming Li

Low-precision networks, with weights and activations quantized to low bit-width, are widely used to accelerate inference on edge devices. However, current solutions are uniform, using identical bit-width for all filters. This fails to…

Machine Learning · Computer Science 2020-04-14 Zhaowei Cai , Nuno Vasconcelos

DNA-binding proteins (DBPs) are integral to gene regulation and cellular processes, making their accurate identification essential for understanding biological functions and disease mechanisms. Experimental methods for DBP identification…

Machine Learning · Computer Science 2025-07-29 Samiul Based Shuvo , Tasnia Binte Mamun , U Rajendra Acharya

When capturing and storing images, devices inevitably introduce noise. Reducing this noise is a critical task called image denoising. Deep learning has become the de facto method for image denoising, especially with the emergence of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Haoyu Chen , Jinjin Gu , Yihao Liu , Salma Abdel Magid , Chao Dong , Qiong Wang , Hanspeter Pfister , Lei Zhu

Decay Replay Mining is a deep learning method that utilizes process model notations to predict the next event. However, this method does not intertwine the neural network with the structure of the process model to its full extent. This…

Machine Learning · Computer Science 2022-04-05 Julian Theis , Houshang Darabi

Deep learning methods have significantly advanced medical image segmentation, yet their success hinges on large volumes of manually annotated data, which require specialized expertise for accurate labeling. Additionally, these methods often…

Image and Video Processing · Electrical Eng. & Systems 2024-09-04 Wangang Cheng , Guanghua He , Keli Hu , Mingyu Fang , Liang Dong , Zhong Li , Hancan Zhu

Dense retrieval is a basic building block of information retrieval applications. One of the main challenges of dense retrieval in real-world settings is the handling of queries containing misspelled words. A popular approach for handling…

In this article, we propose a transfer learning method for deep neural networks (DNNs). Deep learning has been widely used in many applications. However, applying deep learning is problematic when a large amount of training data are not…

Computer Vision and Pattern Recognition · Computer Science 2017-11-15 Yoshihide Sawada , Yoshikuni Sato , Toru Nakada , Kei Ujimoto , Nobuhiro Hayashi

Deep learning based methods have seen a massive rise in popularity for hyperspectral image classification over the past few years. However, the success of deep learning is attributed greatly to numerous labeled samples. It is still very…

Computer Vision and Pattern Recognition · Computer Science 2021-06-30 Bing Liu , Anzhu Yu , Pengqiang Zhang , Lei Ding , Wenyue Guo , Kuiliang Gao , Xibing Zuo

Medical image segmentation using deep neural networks has been highly successful. However, the effectiveness of these networks is often limited by inadequate dense prediction and inability to extract robust features. To achieve refined…

Computer Vision and Pattern Recognition · Computer Science 2024-03-06 Suraj Mishra , Danny Z. Chen

Determinantal Point Processes (DPPs) provide an elegant and versatile way to sample sets of items that balance the point-wise quality with the set-wise diversity of selected items. For this reason, they have gained prominence in many…

Machine Learning · Statistics 2019-01-09 Zelda Mariet , Yaniv Ovadia , Jasper Snoek

Conventional techniques to establish dense correspondences across visually or semantically similar images focused on designing a task-specific matching prior, which is difficult to model. To overcome this, recent learning-based methods have…

Computer Vision and Pattern Recognition · Computer Science 2021-12-16 Sunghwan Hong , Seungryong Kim

The goal of our research is to develop methods advancing automatic visual recognition. In order to predict the unique or multiple labels associated to an image, we study different kind of Deep Neural Networks architectures and methods for…

Computer Vision and Pattern Recognition · Computer Science 2016-10-19 Rémi Cadène , Nicolas Thome , Matthieu Cord