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Related papers: Quantifying Energetic and Entropic Pathways in Mol…

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The information bottleneck (IB) principle has been suggested as a way to analyze deep neural networks. The learning dynamics are studied by inspecting the mutual information (MI) between the hidden layers and the input and output. Notably,…

Machine Learning · Computer Science 2022-02-15 Stephan Sloth Lorenzen , Christian Igel , Mads Nielsen

We developed a machine learning interatomic potential (MLIP) for Ge-rich GeSbTe alloys of interest for applications in phase change memories embedded in microcontrollers. The MLIP was generated by fitting with a neural network method a…

Materials Science · Physics 2026-04-16 Omar Abou El Kheir , Dario Baratella , Marco Bernasconi

Configurational entropy is an important factor in the free energy change of many macromolecular recognition and binding processes, and has been intensively studied. Despite great progresses that have been made, the global sampling remains…

Biological Physics · Physics 2012-12-04 Wenzhao Li , Kai Wang , Suyan Tian , Pu Tian

Stable states in complex systems correspond to local minima on the associated potential energy surface. Transitions between these local minima govern the dynamics of such systems. Precisely determining the transition pathways in complex and…

Machine Learning · Computer Science 2024-10-25 Adittya Pal

In the study of complex dynamical systems, understanding and accurately modeling the underlying physical processes is crucial for predicting system behavior and designing effective interventions. Yet real-world systems exhibit pronounced…

Machine Learning · Statistics 2025-07-15 Ridwan Olabiyi , Han Hu , Ashif Iquebal

We propose a new way of investigating phase transitions in the context of information theory. We use an information-entropic measure of spatial complexity known as configurational entropy (CE) to quantify both the storage and exchange of…

Statistical Mechanics · Physics 2018-03-23 Damian Sowinski , Marcelo Gleiser

In an era where symbolic mathematical equations are indispensable for modeling complex natural phenomena, scientific inquiry often involves collecting observations and translating them into mathematical expressions. Recently, deep learning…

Machine Learning · Computer Science 2024-03-18 Kazem Meidani , Parshin Shojaee , Chandan K. Reddy , Amir Barati Farimani

We introduce a rigorous method to microscopically compute the observables which characterize the thermodynamics and kinetics of rare macromolecular transitions for which it is possible to identify a priori a slow reaction coordinate. In…

Biomolecules · Quantitative Biology 2015-06-05 P. Faccioli , F. Pederiva

In this work we revisit the description of dynamics based on the concepts of metabasins and activation in mildly supercooled liquids via the analysis of the dynamics of a paradigmatic glass former between its onset temperature $T_{o}$ and…

Soft Condensed Matter · Physics 2021-06-15 Marco Baity-Jesi , Giulio Biroli , David R. Reichman

We characterize different cell states, related to cancer and ageing phenotypes, by a measure of entropy of network ensembles, integrating gene expression values and protein interaction networks. The entropy measure estimates the parameter…

Molecular Networks · Quantitative Biology 2013-05-24 G. Menichetti , G. Bianconi , E. Giampieri , G. Castellani , D. Remondini

Metabolic pathways describe chains of enzymatic reactions. Their modelling is a key point to understand living systems. An enzymatic reaction is an interaction between one or several metabolites (substrates) and an enzyme (simple protein or…

Subcellular Processes · Quantitative Biology 2009-01-27 Charles Lales , N. Parisey , Jean-Pierre Mazat , Marie Beurton-Aimar

This paper introduces a method for predicting the likely behaviors of continuous nonlinear systems in equilibrium in which the input values can vary. The method uses a parameterized equation model and a lower bound on the input joint…

Systems and Control · Computer Science 2013-04-10 Alexander Yeh

This work presents a stochastic dynamic programming (SDP) algorithm that aims at minimizing an economic criteria based on the total energy consumption of a range extender electric vehicle (REEV). This algorithm integrates information from…

Optimization and Control · Mathematics 2016-11-18 K. Aouchiche , J. Frederic Bonnans , Giovanni Granato , Hasnaa Zidani

We consider the evolution of a network of neurons, focusing on the asymptotic behavior of spikes dynamics instead of membrane potential dynamics. The spike response is not sought as a deterministic response in this context, but as a…

Data Analysis, Statistics and Probability · Physics 2010-08-27 J. C. Vasquez , B. Cessac , T. Viéville

Some quantum algorithms have "quantum speedups": improved time complexity as compared with the best-known classical algorithms for solving the same tasks. Can we understand what fuels these speedups from an entropic perspective? Information…

Quantum Physics · Physics 2024-11-07 Jason Pollack , Dylan VanAllen

Kramers' rate theory forms a cornerstone for thermally activated barrier crossing. However, its reliance on equilibrium quantities excludes analysis of nonequilibrium dynamics at early times. Most works have thus focused on obtaining rates…

Statistical Mechanics · Physics 2025-09-09 A. J. Archer , T. Ala-Nissila , T. J. W. Honour , S. P. Fitzgerald

Machine-learned interatomic potentials (MLIPs) show promise in accurately describing the physical properties of materials, but there is a need for a higher throughput method of validation. Here, we demonstrate using that MLIPs and molecular…

Materials Science · Physics 2023-03-07 Dennis S. Kim , Michael Xu , James M. LeBeau

A system of neutral atoms trapped in an optical lattice and dispersively coupled to the field of an optical cavity can realize a variation of the Bose-Hubbard model with infinite-range interactions. This model exhibits a first order quantum…

Quantum Physics · Physics 2018-02-09 Sascha Wald , Andre Timpanaro , Cecilia Cormick , Gabriel T. Landi

We propose a new mechanism to alter the nature of the potential barriers when a biased Brownian particle under goes a constrained motion in narrow, periodic channel. By changing the angle of the external bias, the nature of the potential…

Statistical Mechanics · Physics 2010-12-06 P. S. Burada , G. Schmid

We introduce the notion of importance sampling under embedded barrier state control, titled Safety Controlled Model Predictive Path Integral Control (SC-MPPI). For robotic systems operating in an environment with multiple constraints, hard…

Systems and Control · Electrical Eng. & Systems 2023-03-08 Manan Gandhi , Hassan Almubarak , Evangelos Theodorou