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We prove that the stochastic Burgers equation, which is related to the Kardar-Parisi-Zhang/KPZ equation via weak derivative, is a "critical" scaling limit for density fluctuations for a family of non-integrable and non-stationary…

Probability · Mathematics 2022-03-01 Kevin Yang

In this paper, we address an optimal distributed control problem for a non-local model of phase-field type, describing the evolution of tumour cells in presence of a nutrient. The model couples a non-local and viscous Cahn-Hilliard equation…

Analysis of PDEs · Mathematics 2023-10-25 Matteo Fornoni

We study the existence of large solutions for nonlocal Dirichlet problems posed on a bounded, smooth domain, associated to fully nonlinear elliptic equations of order $2s$, with $s\in (1/2,1)$, and a coercive gradient term with subcritical…

Analysis of PDEs · Mathematics 2022-03-25 Gonzalo Dávila , Alexander Quaas , Erwin Topp

We consider a biphasic continuum model for avascular tumour growth in two spatial dimensions, in which a cell phase and a fluid phase follow conservation of mass and momentum. A limiting nutrient that follows a diffusion process controls…

Numerical Analysis · Mathematics 2020-10-21 Jerome Droniou , Jennifer A. Flegg , Gopikrishnan C. Remesan

Strong experimental evidence has indicated that tumor growth belongs to the molecular beam epitaxy universality class. This type of growth is characterized by the constraint of cell proliferation to the tumor border, and surface diffusion…

Quantitative Methods · Quantitative Biology 2009-11-13 Carlos Escudero

Cell-cell adhesion is an inherently nonlocal phenomenon. Numerous partial differential equation models with nonlocal term have been recently presented to describe this phenomenon, yet the mathematical properties of nonlocal adhesion model…

Analysis of PDEs · Mathematics 2021-03-17 Jaewook Ahn , Myeongju Chae , Jihoon Lee

Theoretical and computational tools that can be used in the clinic to predict neoplastic progression and propose individualized optimal treatment strategies to control cancer growth is desired. To develop such a predictive model, one must…

Cell Behavior · Quantitative Biology 2015-05-20 Salvatore Torquato

A coupled system of nonlinear mixed-type equations modeling early stages of angiogenesis is analyzed in a bounded domain. The system consists of stochastic differential equations describing the movement of the positions of the tip and stalk…

Analysis of PDEs · Mathematics 2022-06-24 Markus Fellner , Ansgar Jüngel

We consider the stochastic heat equation $\partial_tZ= \partial_x^2 Z - Z \dot W$ on the real line, where $\dot W$ is space-time white noise. $h(t,x)=-\log Z(t,x)$ is interpreted as a solution of the KPZ equation, and $u(t,x)=\partial_x…

Probability · Mathematics 2011-10-20 Marton Balazs , Jeremy Quastel , Timo Seppalainen

In this work, we consider a diffuse interface model for tumour growth in the presence of a nutrient which is consumed by the tumour. The system of equations consists of a Cahn--Hilliard equation with source terms for the tumour cells and a…

Numerical Analysis · Mathematics 2022-05-09 Harald Garcke , Dennis Trautwein

In this article we study generalizations of the inhomogeneous Burgers equation. First at the operator level, in the sense that we replace classical differential derivations by operators with certain properties, and then we increase the…

Analysis of PDEs · Mathematics 2024-11-08 Francesco Maltese

In this paper, we propose a new mathematical model nonlinear reaction-diffusion PDE's describing the dynamics of propagation of cancer. Here the mixed problem for the proposed PDE's is investigated and by applying obtained results…

Analysis of PDEs · Mathematics 2022-01-10 Kamal N. Soltanov

Most cancers in humans are large, measuring centimeters in diameter, composed of many billions of cells. An equivalent mass of normal cells would be highly heterogeneous as a result of the mutations that occur during each cell division.…

Populations and Evolution · Quantitative Biology 2016-02-17 Bartlomiej Waclaw , Ivana Bozic , Meredith E. Pittman , Ralph H. Hruban , Bert Vogelstein , Martin A. Nowak

Local and global well-posedness, along with finite time blow-up, are investigated for the following Hardy-H\'enon equation involving a quasilinear degenerate diffusion and a space-dependent superlinear source featuring a singular potential…

Analysis of PDEs · Mathematics 2025-03-06 Razvan Gabriel Iagar , Philippe Laurençot

We further study the stochastic model discussed in Ref.[2] in which positive and negative particles diffuse in an asymmetric, CP invariant way on a ring. The positive particles hop clockwise, the negative counter-clockwise and…

Statistical Mechanics · Physics 2007-05-23 Peter F. Arndt , Vladimir Rittenberg

In this paper we introduce a new PDE model in frequency space for the inertial energy cascade that reproduces the classical scaling laws of Kolmogorov's theory of turbulence. Our point of view is based upon studying the energy flux through…

Analysis of PDEs · Mathematics 2011-12-23 Alexey Cheskidov , Susan Friedlander , Roman Shvydkoy

In this paper, we consider the following parabolic-parabolic-elliptic system } \begin{align*} \left\{\aligned & u_t=\Delta u-\nabla\cdot(u\nabla v)+\xi\nabla\cdot(u\nabla w)+au-\mu u^{\alpha}, && x\in\Omega, t>0,\\ & v_t=\Delta…

Analysis of PDEs · Mathematics 2024-05-28 Fengxiang Zhao , Jiashan Zheng , Kaiqiang Li

In this paper, we derive a new chemotaxis model with degenerate diffusion and density-dependent chemotactic sensitivity, and we provide a more realistic description of cell migration process for its early and late stages. Different from the…

Analysis of PDEs · Mathematics 2023-07-19 Tianyuan Xu , Shanming Ji , Chunhua Jin , Ming Mei , Jingxue Yin

We present a multiphase mathematical model for tumor growth which incorporates the remodeling of the extracellular matrix and describes the formation of fibrotic tissue by tumor cells. We also detail a full qualitative analysis of the…

Mathematical Physics · Physics 2010-08-09 Andrea Tosin , Luigi Preziosi

We consider a phenotype-structured reaction-diffusion model of avascular glioma growth. The model describes the interaction dynamics between tumour cells and oxygen, and takes into account anisotropic cell movement and oxygen diffusion…

Populations and Evolution · Quantitative Biology 2025-09-29 Francesca Ballatore , Xinran Ruan , Chiara Giverso , Tommaso Lorenzi