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Uncertainty Quantification (UQ) is a promising approach to improve model reliability, yet quantifying the uncertainty of Large Language Models (LLMs) is non-trivial. In this work, we establish a connection between the uncertainty of LLMs…

Computation and Language · Computer Science 2025-10-16 Mingda Li , Xinyu Li , Weinan Zhang , Longxuan Ma

To improve the reliability of Large Language Models (LLMs) in clinical applications, retrieval-augmented generation (RAG) is extensively applied to provide factual medical knowledge. However, beyond general medical knowledge from open-ended…

Computation and Language · Computer Science 2025-05-29 Justice Ou , Tinglin Huang , Yilun Zhao , Ziyang Yu , Peiqing Lu , Rex Ying

Electronic medical records (EMRs) are stored in relational databases. It can be challenging to access the required information if the user is unfamiliar with the database schema or general database fundamentals. Hence, researchers have…

Computation and Language · Computer Science 2023-03-24 Richard Tarbell , Kim-Kwang Raymond Choo , Glenn Dietrich , Anthony Rios

Recent advances in Large Language Models (LLMs) have enabled the development of text-to-SQL models that allow clinicians to query structured data stored in Electronic Health Records (EHRs) using natural language. However, deploying these…

Computation and Language · Computer Science 2025-12-23 Gyubok Lee , Woosog Chay , Edward Choi

Machine Reading Comprehension (MRC) holds a pivotal role in shaping Medical Question Answering Systems (QAS) and transforming the landscape of accessing and applying medical information. However, the inherent challenges in the medical…

Computation and Language · Computer Science 2024-04-19 Jimenez Eladio , Hao Wu

Electronic Health Records (EHRs) contain rich yet complex information, and their automated analysis is critical for clinical decision-making. Despite recent advances of large language models (LLMs) in clinical workflows, their ability to…

Computation and Language · Computer Science 2025-11-26 Yusheng Liao , Chaoyi Wu , Junwei Liu , Shuyang Jiang , Pengcheng Qiu , Haowen Wang , Yun Yue , Shuai Zhen , Jian Wang , Qianrui Fan , Jinjie Gu , Ya Zhang , Yanfeng Wang , Yu Wang , Weidi Xie

Large language models (LLMs) have demonstrated exceptional capabilities in planning and tool utilization as autonomous agents, but few have been developed for medical problem-solving. We propose EHRAgent, an LLM agent empowered with a code…

Computation and Language · Computer Science 2024-10-07 Wenqi Shi , Ran Xu , Yuchen Zhuang , Yue Yu , Jieyu Zhang , Hang Wu , Yuanda Zhu , Joyce Ho , Carl Yang , May D. Wang

Electronic health records (EHRs) are stored in various database systems with different database models on heterogeneous storage architectures, such as relational databases, document stores, or graph databases. These different database…

Databases · Computer Science 2024-11-15 Sithursan Sivasubramaniam , Cedric Osei-Akoto , Yi Zhang , Kurt Stockinger , Jonathan Fuerst

Extractive question answering (QA) systems can enable physicians and researchers to query medical records, a foundational capability for designing clinical studies and understanding patient medical history. However, building these systems…

Computation and Language · Computer Science 2023-12-07 Joel Stremmel , Ardavan Saeedi , Hamid Hassanzadeh , Sanjit Batra , Jeffrey Hertzberg , Jaime Murillo , Eran Halperin

Electronic health records (EHRs), digital collections of patient healthcare events and observations, are ubiquitous in medicine and critical to healthcare delivery, operations, and research. Despite this central role, EHRs are notoriously…

Large Language Models (LLMs) have excelled in multi-hop question-answering (M-QA) due to their advanced reasoning abilities. However, the impact of the inherent reasoning structures on LLM M-QA performance remains unclear, largely due to…

Unstructured clinical notes contain essential patient information but are challenging for physicians to search and interpret efficiently. Although large language models (LLMs) have shown promise in question answering (QA), most existing…

Human-Computer Interaction · Computer Science 2025-05-27 Dina Albassam

Electronic Health Records (EHR) systematically organize patient health data through standardized medical codes, serving as a comprehensive and invaluable source for predictive modeling. Graph neural networks (GNNs) have demonstrated…

Machine Learning · Computer Science 2025-08-29 Haiyan Wang , Ye Yuan

Large Language Models (LLMs) have demonstrated remarkable capabilities across various tasks due to large training datasets and powerful transformer architecture. However, the reliability of responses from LLMs remains a question.…

Computation and Language · Computer Science 2025-02-26 Tiejin Chen , Xiaoou Liu , Longchao Da , Jia Chen , Vagelis Papalexakis , Hua Wei

Electronic health records (EHR) are widely believed to hold a profusion of actionable insights, encrypted in an irregular, semi-structured format, amidst a loud noise background. To simplify learning patterns of health and disease, medical…

Computation and Language · Computer Science 2022-12-13 David A. Bloore , Romane Gauriau , Anna L. Decker , Jacob Oppenheim

Patients have distinct information needs about their hospitalization that can be addressed using clinical evidence from electronic health records (EHRs). While artificial intelligence (AI) systems show promise in meeting these needs, robust…

Computation and Language · Computer Science 2026-03-31 Sarvesh Soni , Dina Demner-Fushman

Electronic Health Record (EHR) tables pose unique challenges among which is the presence of hidden contextual dependencies between medical features with a high level of data dimensionality and sparsity. This study presents the first…

Computation and Language · Computer Science 2025-01-17 Jesus Lovon , Martin Mouysset , Jo Oleiwan , Jose G. Moreno , Christine Damase-Michel , Lynda Tamine

Question answering over Scholarly Knowledge Graphs (SKGs) remains a challenging task due to the complexity of scholarly content and the intricate structure of these graphs. Large Language Model (LLM) approaches could be used to translate…

Artificial Intelligence · Computer Science 2025-08-15 Xueli Pan , Victor de Boer , Jacco van Ossenbruggen

Structured Electronic Health Record (EHR) data stores patient information in relational tables and plays a central role in clinical decision-making. Recent advances have explored the use of large language models (LLMs) to process such data,…

Artificial Intelligence · Computer Science 2026-04-02 Xiao Yang , Xuejiao Zhao , Zhiqi Shen

This paper introduces MedExQA, a novel benchmark in medical question-answering, to evaluate large language models' (LLMs) understanding of medical knowledge through explanations. By constructing datasets across five distinct medical…

Computation and Language · Computer Science 2024-07-04 Yunsoo Kim , Jinge Wu , Yusuf Abdulle , Honghan Wu