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In survival analysis it often happens that some subjects under study do not experience the event of interest; they are considered to be `cured'. The population is thus a mixture of two subpopulations: the one of cured subjects, and the one…

Statistics Theory · Mathematics 2017-01-16 Valentin Patilea , Ingrid Van Keilegom

We propose a highly flexible distributional copula regression model for bivariate time-to-event data in the presence of right-censoring. The joint survival function of the response is constructed using parametric copulas, allowing for a…

Methodology · Statistics 2024-12-23 Guillermo Briseno-Sanchez , Nadja Klein , Andreas Groll , Andreas Mayr

We propose a flexible Bayesian approach for estimating the joint density of a multivariate outcome of interest in the presence of categorical covariates. Leveraging a Gaussian copula framework, our method effectively captures the dependence…

Methodology · Statistics 2026-04-10 Giovanni Toto , Peter Müller , Abhra Sarkar

In this paper, a family of neural network-based survival models is presented. The models are specified based on piecewise definitions of the hazard function and the density function on a partitioning of the time; both constant and linear…

Machine Learning · Statistics 2024-03-28 Olov Holmer , Erik Frisk , Mattias Krysander

Network meta-analysis (NMA) is widely used in healthcare decision-making, where estimates of the effect of multiple treatments on outcomes are required. For time-to-event outcomes such as survival or disease progression the most common…

Methodology · Statistics 2025-09-15 David M. Phillippo , Ayman Sadek , Hugo Pedder , Nicky J. Welton

Spatial survival analysis has received a great deal of attention over the last 20 years due to the important role that geographical information can play in predicting survival. This paper provides an introduction to a set of programs for…

Computation · Statistics 2018-04-25 Haiming Zhou , Timothy Hanson , Jiajia Zhang

We consider a general proportional odds model for survival data under binary treatment, where the functional form of the covariates is left unspecified. We derive the efficient score for the conditional survival odds ratio given the…

Methodology · Statistics 2024-05-16 Denise Rava , Jelena Bradic , Ronghui Xu

Consider a continuous random pair $(X,Y)$ whose dependence is characterized by an extreme-value copula with Pickands dependence function $A$. When the marginal distributions of $X$ and $Y$ are known, several consistent estimators of $A$ are…

Statistics Theory · Mathematics 2009-08-26 Christian Genest , Johan Segers

Survival analysis is widely deployed in a diverse set of fields, including healthcare, business, ecology, etc. The Cox Proportional Hazard (CoxPH) model is a semi-parametric model often encountered in the literature. Despite its popularity,…

Machine Learning · Computer Science 2025-05-29 Chengzhi Shi , Stratis Ioannidis

Frailty models are essential tools in survival analysis for addressing unobserved heterogeneity and random effects in the data. These models incorporate a random effect, the frailty, which is assumed to impact the hazard rate…

Statistics Theory · Mathematics 2025-04-01 Jorge Yslas

This study introduces the Exponentiated-Exponential-Pareto-Half Normal Mixture Distribution (EEPHND), a novel hybrid model developed to overcome the limitations of classical distributions in modeling complex real-world data. By compounding…

Survival Analysis (SA) constitutes the default method for time-to-event modeling due to its ability to estimate event probabilities of sparsely occurring events over time. In this work, we show how to improve the training and inference of…

Machine Learning · Computer Science 2023-12-12 Chris Solomou

We propose a class of transformation hazard models for right-censored failure time data. It includes the proportional hazards model (Cox) and the additive hazards model (Lin and Ying) as special cases. Due to the requirement of a…

Statistics Theory · Mathematics 2007-06-13 Gousheng Yin , Joseph G. Ibrahim

Hereby we propose a Bayesian method of estimation for the semiparametric Additive Hazards Model (AHM) from Survival Analysis under right-censoring. With this aim, we review the AHM revisiting the likelihood function, so as to comment on the…

Methodology · Statistics 2025-05-28 Enrique Ernesto Álvarez , Maximiliano Luis Riddick

In biomedical studies, paired survival data arise naturally when two event times are observed within the same subject. Existing statistical models seldom accommodate both cure fractions and complex dependence structures. In this paper, we…

Methodology · Statistics 2026-04-28 Masaki Hino , Shogo Kato , Takeshi Emura

Balanced representation learning methods have been applied successfully to counterfactual inference from observational data. However, approaches that account for survival outcomes are relatively limited. Survival data are frequently…

Machine Learning · Statistics 2021-03-04 Paidamoyo Chapfuwa , Serge Assaad , Shuxi Zeng , Michael J. Pencina , Lawrence Carin , Ricardo Henao

This article extends the literature on copulas with discrete or continuous marginals to the case where some of the marginals are a mixture of discrete and continuous components. We do so by carefully defining the likelihood as the density…

Methodology · Statistics 2017-09-05 David Gunawan , Mohamad A. Khaled , Robert Kohn

Regression models have a substantial impact on interpretation of treatments, genetic characteristics and other potential risk factors in survival analysis. In many applications, the description of censoring and survival curve reveals the…

Methodology · Statistics 2026-03-24 Dionisio Alves-Neto , Vera Lucia Tomazella , Adriano Suzuki , Danilo Alvares

We describe a simple method for making inference on a functional of a multivariate distribution. The method is based on a copula representation of the multivariate distribution and it is based on the properties of an Approximate Bayesian…

Methodology · Statistics 2017-07-18 Clara Grazian , Brunero Liseo

With known cause of death (CoD), competing risk survival methods are applicable in estimating disease-specific survival. Relative survival analysis may be used to estimate disease-specific survival when cause of death is either unknown or…

Methodology · Statistics 2021-12-10 Reuben Adatorwovor , Aurelien Latouche , Jason P. Fine