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Panoptic Segmentation aims to provide an understanding of background (stuff) and instances of objects (things) at a pixel level. It combines the separate tasks of semantic segmentation (pixel level classification) and instance segmentation…

Computer Vision and Pattern Recognition · Computer Science 2021-04-07 Sumanth Chennupati , Venkatraman Narayanan , Ganesh Sistu , Senthil Yogamani , Samir A Rawashdeh

Semantic and instance segmentation algorithms are two general yet distinct image segmentation solutions powered by Convolution Neural Network. While semantic segmentation benefits extensively from the end-to-end training strategy, instance…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Jianfeng Cao , Hong Yan

The analysis of glandular morphology within colon histopathology images is an important step in determining the grade of colon cancer. Despite the importance of this task, manual segmentation is laborious, time-consuming and can suffer from…

Computer Vision and Pattern Recognition · Computer Science 2019-02-19 Simon Graham , Hao Chen , Jevgenij Gamper , Qi Dou , Pheng-Ann Heng , David Snead , Yee Wah Tsang , Nasir Rajpoot

Histopathology image analysis plays a critical role in cancer diagnosis and treatment. To automatically segment the cancerous regions, fully supervised segmentation algorithms require labor-intensive and time-consuming labeling at the pixel…

Image and Video Processing · Electrical Eng. & Systems 2019-08-29 Gang Xu , Zhigang Song , Zhuo Sun , Calvin Ku , Zhe Yang , Cancheng Liu , Shuhao Wang , Jianpeng Ma , Wei Xu

Breast cancer is one of the most serious types of cancer that can occur in women. The automatic diagnosis of breast cancer by analyzing histological images (HIs) is important for patients and their prognosis. The classification of HIs…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Hayder A. Khikani , Naira Elazab , Ahmed Elgarayhi , Mohammed Elmogy , Mohammed Sallah

Instance segmentation aims to delineate each individual object of interest in an image. State-of-the-art approaches achieve this goal by either partitioning semantic segmentations or refining coarse representations of detected objects. In…

Computer Vision and Pattern Recognition · Computer Science 2022-10-10 Long Chen , Yuli Wu , Dorit Merhof

Histopathology remains the gold standard for cancer diagnosis because it provides detailed cellular-level assessment of tissue morphology. However, manual histopathological examination is time-consuming, labour-intensive, and subject to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ravi Mosalpuri , Mohammed Abdelsamea , Ahmed Karam Eldaly

Empirical evaluation of breast tissue biopsies for mitotic nuclei detection is considered an important prognostic biomarker in tumor grading and cancer progression. However, automated mitotic nuclei detection poses several challenges…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Anabia Sohail , Muhammad Ahsan Mukhtar , Asifullah Khan , Muhammad Mohsin Zafar , Aneela Zameer , Saranjam Khan

Histopathological imaging is vital for cancer research and clinical practice, with multiplexed Immunofluorescence (MxIF) and Hematoxylin and Eosin (H&E) providing complementary insights. However, aligning different stains at the cell level…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Jun Jiang , Raymond Moore , Brenna Novotny , Leo Liu , Zachary Fogarty , Ray Guo , Markovic Svetomir , Chen Wang

Identify the cells' nuclei is the important point for most medical analyses. To assist doctors finding the accurate cell' nuclei location automatically is highly demanded in the clinical practice. Recently, fully convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Tianyang Zhang , Rui Ma

Treatment approaches for colorectal cancer (CRC) are highly dependent on the molecular subtype, as immunotherapy has shown efficacy in cases with microsatellite instability (MSI) but is ineffective for the microsatellite stable (MSS)…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Hadar Hezi , Matan Gelber , Alexander Balabanov , Yosef E. Maruvka , Moti Freiman

Histopathological image segmentation is a challenging and important topic in medical imaging with tremendous potential impact in clinical practice. State of the art methods rely on hand-crafted annotations which hinder clinical translation…

Numerous deep learning based methods have been developed for nuclei segmentation for H&E images and have achieved close to human performance. However, direct application of such methods to another modality of images, such as…

Computer Vision and Pattern Recognition · Computer Science 2022-08-15 Roger Trullo , Quoc-Anh Bui , Qi Tang , Reza Olfati-Saber

Parotid gland tumor is a common type of head and neck tumor. Segmentation of the parotid glands and tumors by MR images is important for the treatment of parotid gland tumors. However, segmentation of the parotid glands is particularly…

Computer Vision and Pattern Recognition · Computer Science 2022-12-27 Zi'an Xu , Yin Dai , Fayu Liu , Boyuan Wu , Weibing Chen , Lifu Shi

This work proposed a novel learning objective to train a deep neural network to perform end-to-end image pixel clustering. We applied the approach to instance segmentation, which is at the intersection of image semantic segmentation and…

Computer Vision and Pattern Recognition · Computer Science 2018-03-20 Yen-Chang Hsu , Zheng Xu , Zsolt Kira , Jiawei Huang

Nuclei segmentation is a fundamental prerequisite in the digital pathology workflow. The development of automated methods for nuclei segmentation enables quantitative analysis of the wide existence and large variances in nuclei morphometry…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Yi Lin , Zeyu Wang , Dong Zhang , Kwang-Ting Cheng , Hao Chen

Background: Cell segmentation in bright-field histological slides is a crucial topic in medical image analysis. Having access to accurate segmentation allows researchers to examine the relationship between cellular morphology and clinical…

We present SurfDist, a convolutional neural network architecture for three-dimensional volumetric instance segmentation. SurfDist enables prediction of instances represented as closed surfaces composed of smooth parametric surface patches,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Jackson Borchardt , Saul Kato

This paper presents a novel unsupervised segmentation method for 3D medical images. Convolutional neural networks (CNNs) have brought significant advances in image segmentation. However, most of the recent methods rely on supervised…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Takayasu Moriya , Holger R. Roth , Shota Nakamura , Hirohisa Oda , Kai Nagara , Masahiro Oda , Kensaku Mori

Instance Segmentation, which seeks to obtain both class and instance labels for each pixel in the input image, is a challenging task in computer vision. State-of-the-art algorithms often employ two separate stages, the first one generating…

Computer Vision and Pattern Recognition · Computer Science 2020-10-27 Jialin Yuan , Chao Chen , Li Fuxin