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Scanning transmission electron microscopy (STEM) has advanced rapidly in the last decade thanks to the ability to correct the major aberrations of the probe forming lens. Now atomic-sized beams are routine, even at accelerating voltages as…

Coherent spin resonance methods such as nuclear magnetic resonance (NMR) and electron spin resonance (ESR) spectroscopy have led to spectrally highly sensitive, non-invasive quantum imaging techniques with groundbreaking applications in…

Various representation learning methods for molecular structures have been devised to accelerate data-driven chemistry. However, the representation capabilities of existing methods are essentially limited to atom-level information, which is…

Chemical Physics · Physics 2026-02-10 Gyoung S. Na , Chanyoung Park

While offering unprecedented resolution of atomic and electronic structure, Scanning Probe Microscopy techniques have found greater challenges in providing reliable electrostatic characterization at the same scale. In this work, we…

Electron energy-loss spectroscopy (EELS) coupled with scanning transmission electron microscopy (STEM) is a powerful technique to determine materials composition and bonding with high spatial resolution. Noise is often a limitation…

Instrumentation and Detectors · Physics 2025-05-21 Yifan Wang , Mai Tan , Carlos Fernandez-Granda , Peter A. Crozier

Molecular self-assembly, the function of biomembranes, and the performance of organic solar cells rely on molecular interactions on the nanoscale. The understanding and design of such intrinsic or engineered heterogeneous functional soft…

Chemical Physics · Physics 2013-12-30 Benjamin Pollard , Eric A. Muller , Karsten Hinrichs , Markus B. Raschke

Energy dispersive X-ray (EDX) spectrum imaging yields compositional information with a spatial resolution down to the atomic level. However, experimental limitations often produce extremely sparse and noisy EDX spectra. Under such…

The ongoing miniaturization in nanoscience and -technology challenges the sensitivity and selectivity of experimental analysis methods to the ultimate level of single atoms and molecules. A promising new approach, addressed here, focuses on…

Mesoscale and Nanoscale Physics · Physics 2014-03-28 Stefan Müllegger , Stefano Tebi , Amal K. Das , Wolfgang Schöfberger , Felix Faschinger , Reinhold Koch

Combining microfluidic devices with nuclear magnetic resonance (NMR) has the potential of unlocking their vast sample handling and processing operation space for use with the powerful analytics provided by NMR. One particularly challenging…

We propose a novel Graph Neural Network-based method for segmentation based on data fusion of multimodal Scanning Electron Microscope (SEM) images. In most cases, Backscattered Electron (BSE) images obtained using SEM do not contain…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Samuel Repka , Bořek Reich , Fedor Zolotarev , Tuomas Eerola , Pavel Zemčík

Nuclear magnetic resonance (NMR) spectroscopy is a widely used tool for chemical analysis and molecular structure identification. Because it typically relies on the weak magnetic fields produced by a small thermal nuclear spin polarization,…

Applied Physics · Physics 2020-06-11 Dominik B. Bucher , David R. Glenn , Hongkun Park , Mikhail D. Lukin , Ronald L. Walsworth

Magnetic spin resonance is a key non-invasive sensing and imaging technique across the life-, material- and fundamental sciences with further medical and commercial applications. Recent advances using paramagnetic color centers enable…

Mesoscale and Nanoscale Physics · Physics 2018-07-24 Florestan Ziem , Marwa Garsi , Helmut Fedder , Jörg Wrachtrup

Spectroscopic techniques are essential tools for determining the structure of molecules. Different spectroscopic techniques, such as Nuclear magnetic resonance (NMR), Infrared spectroscopy, and Mass Spectrometry, provide insight into the…

Chemical Physics · Physics 2024-10-30 Marvin Alberts , Oliver Schilter , Federico Zipoli , Nina Hartrampf , Teodoro Laino

X-ray microspectroscopic techniques are essential for studying morphological and chemical changes in materials, providing high-resolution structural and spectroscopic information. However, its practical data analysis for reliably retrieving…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Ting Wang , Xiaotong Wu , Jizhou Li , Chao Wang

The non-destructive characterization of nanoscale devices, such as those based on semiconductor nanowires, in terms of functional potentials is crucial for correlating device properties with their morphological/materials features, as well…

Mesoscale and Nanoscale Physics · Physics 2018-10-10 Daniel Wolf , René Hübner , Tore Niermann , Sebastian Sturm , Paola Prete , Nico Lovergine , Bernd Büchner , Axel Lubk

Electron energy-loss spectroscopy (EELS) can measure similar information to X-ray, UV-Vis, and IR spectroscopies but with atomic resolution and increased scattering cross sections. Recent advances in electron monochromators have expanded…

Chemical Physics · Physics 2024-04-26 Ye-Jin Kim , Levi D. Palmer , Wonseok Lee , Nicholas J. Heller , Scott K. Cushing

The use of Standard Reference Materials (SRM) from the National Institute of Standards and Technology (NIST) for quantitative analysis of chemical composition using Synchrotron based X-Ray Florescence (SR-XRF) and Scanning Transmission…

Nanoparticle surface structural dynamics is believed to play a significant role in regulating functionalities such as diffusion, reactivity, and catalysis but the atomic-level processes are not well understood. Atomic resolution…

Interest in the magnetism of organic compounds is growing because of new organic magnets, spin-based electronics and the diverse properties of magnetic edge states in graphene nanoribbons. Electron spin resonance spectroscopy combined with…

Mesoscale and Nanoscale Physics · Physics 2025-04-28 Gregory Czap , Christoph Wolf , Jose Reina-Gálvez , Mark H. Sherwood , Christopher P. Lutz

Correlative light and electron microscopy promises to combine molecular specificity with nanoscale imaging resolution. However, there are substantial technical challenges including reliable co-registration of optical and electron images,…