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Nuclei segmentation is a crucial task for whole slide image analysis in digital pathology. Generally, the segmentation performance of fully-supervised learning heavily depends on the amount and quality of the annotated data. However, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Yi Lin , Zhiyong Qu , Hao Chen , Zhongke Gao , Yuexiang Li , Lili Xia , Kai Ma , Yefeng Zheng , Kwang-Ting Cheng

We propose a new and, arguably, a very simple reduction of instance segmentation to semantic segmentation. This reduction allows to train feed-forward non-recurrent deep instance segmentation systems in an end-to-end fashion using…

Computer Vision and Pattern Recognition · Computer Science 2018-07-27 Victor Kulikov , Victor Yurchenko , Victor Lempitsky

Nucleus segmentation is usually the first step in pathological image analysis tasks. Generalizable nucleus segmentation refers to the problem of training a segmentation model that is robust to domain gaps between the source and target…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Shengcong Chen , Changxing Ding , Dacheng Tao , Hao Chen

Nuclear instance segmentation has played a critical role in pathology image analysis. The main challenges arise from the difficulty in accurately segmenting instances and the high cost of precise mask-level annotations for fully-supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Peng Ling , Wenxiao Xiong

Few-shot Semantic Segmentation addresses the challenge of segmenting objects in query images with only a handful of annotated examples. However, many previous state-of-the-art methods either have to discard intricate local semantic features…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Amirreza Fateh , Mohammad Reza Mohammadi , Mohammad Reza Jahed Motlagh

Nuclei segmentation is both an important and in some ways ideal task for modern computer vision methods, e.g. convolutional neural networks. While recent developments in theory and open-source software have made these tools easier to…

Computer Vision and Pattern Recognition · Computer Science 2019-01-30 Aarno Oskar Vuola , Saad Ullah Akram , Juho Kannala

Convolutional neural nets (CNN) are the leading computer vision method for classifying images. In some cases, it is desirable to classify only a specific region of the image that corresponds to a certain object. Hence, assuming that the…

Computer Vision and Pattern Recognition · Computer Science 2018-12-07 Sagi Eppel

Convolutional blocks have played a crucial role in advancing medical image segmentation by excelling in dense prediction tasks. However, their inability to effectively capture long-range dependencies has limited their performance.…

Image and Video Processing · Electrical Eng. & Systems 2026-03-17 Siddhartha Mallick , Aayushman Ghosh , Jayanta Paul , Jaya Sil

Automated cell nucleus segmentation and classification are required to assist pathologists in their decision making. The Colon Nuclei Identification and Counting Challenge 2022 (CoNIC Challenge 2022) supports the development and…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Moritz Böhland , Oliver Neumann , Marcel P. Schilling , Markus Reischl , Ralf Mikut , Katharina Löffler , Tim Scherr

Automatic nuclei segmentation and classification play a vital role in digital pathology. However, previous works are mostly built on data with limited diversity and small sizes, making the results questionable or misleading in actual…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Kai Yao , Kaizhu Huang , Jie Sun , Amir Hussain

Separating and labeling each instance of a nucleus (instance-aware segmentation) is the key challenge in segmenting single cell nuclei on fluorescence microscopy images. Deep Neural Networks can learn the implicit transformation of a…

Computer Vision and Pattern Recognition · Computer Science 2021-08-11 Florian Kromp , Lukas Fischer , Eva Bozsaky , Inge Ambros , Wolfgang Doerr , Sabine Taschner-Mandl , Peter Ambros , Allan Hanbury

Cell instance segmentation is critical to analyzing biomedical images, yet accurately distinguishing tightly touching cells remains a persistent challenge. Existing instance segmentation frameworks, including detection-based, contour-based,…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Ye Zhang , Yu Zhou , Yifeng Wang , Jun Xiao , Ziyue Wang , Yongbing Zhang , Jianxu Chen

Separating overlapped nuclei is a major challenge in histopathology image analysis. Recently published approaches have achieved promising overall performance on nuclei segmentation; however, their performance on separating overlapped nuclei…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Haotian Wang , Aleksandar Vakanski , Changfa Shi , Min Xian

Nuclei segmentation is a fundamental prerequisite in the digital pathology workflow. The development of automated methods for nuclei segmentation enables quantitative analysis of the wide existence and large variances in nuclei morphometry…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Yi Lin , Zeyu Wang , Dong Zhang , Kwang-Ting Cheng , Hao Chen

Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

Quantitative Methods · Quantitative Biology 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim

Color image segmentation is a very emerging research topic in the area of color image analysis and pattern recognition. Many state-of-the-art algorithms have been developed for this purpose. But, often the segmentation results of these…

Computer Vision and Pattern Recognition · Computer Science 2017-08-18 Dibya Jyoti Bora

This paper explores the segmentation of very small medical objects with significant clinical value. While Convolutional Neural Networks (CNNs), particularly UNet-like models, and recent Transformers have shown substantial progress in image…

Image and Video Processing · Electrical Eng. & Systems 2024-06-27 Lingjie Kong , Qiaoling Wei , Chengming Xu , Han Chen , Yanwei Fu

Image recognition tasks that involve identifying parts of an object or the contents of a vessel can be viewed as a hierarchical problem, which can be solved by initial recognition of the main object, followed by recognition of its parts or…

Computer Vision and Pattern Recognition · Computer Science 2017-10-17 Sagi Eppel

Volumetric cell segmentation in fluorescence microscopy images is important to study a wide variety of cellular processes. Applications range from the analysis of cancer cells to behavioral studies of cells in the embryonic stage. Like in…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Royden Wagner , Karl Rohr

Convolutional Neural Networks (CNNs) have been recently employed to solve problems from both the computer vision and medical image analysis fields. Despite their popularity, most approaches are only able to process 2D images while most…

Computer Vision and Pattern Recognition · Computer Science 2016-06-16 Fausto Milletari , Nassir Navab , Seyed-Ahmad Ahmadi