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Oral epithelial dysplasia (OED) is a pre-malignant histopathological diagnosis given to lesions of the oral cavity. Predicting OED grade or whether a case will transition to malignancy is critical for early detection and appropriate…

Image and Video Processing · Electrical Eng. & Systems 2021-09-02 Adam J. Shephard , Simon Graham , R. M. Saad Bashir , Mostafa Jahanifar , Hanya Mahmood , Syed Ali Khurram , Nasir M. Rajpoot

Histopathology image analysis is critical yet challenged by the demand of segmenting tissue regions and nuclei instances for tumor microenvironment and cellular morphology analysis. Existing studies focused on tissue semantic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Qing Xu , Wenting Duan , Zhen Chen

Recent developments in self-supervised learning give us the possibility to further reduce human intervention in multi-step pipelines where the focus evolves around particular objects of interest. In the present paper, the focus lays in the…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Peter Naylor , Yao-Hung Hubert Tsai , Marick Laé , Makoto Yamada

Nuclear segmentation in histology images is a challenging task due to significant variations in the shape and appearance of nuclei. One of the main hurdles in nuclear instance segmentation is overlapping nuclei where a smart algorithm is…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Navid Alemi Koohbanani , Mostafa Jahanifar , Ali Gooya , Nasir Rajpoot

Segmentation is one of the most significant steps in image processing. Segmenting an image is a technique that makes it possible to separate a digital image into various areas based on the different characteristics of pixels in the image.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Sina Derakhshandeh , Ali Mahloojifar

The growing complexity and scale of image processing tasks challenge classical convolutional neural networks (CNNs) with high computational costs. Hybrid quantum-classical convolutional neural networks (HQCNNs) show potential to improve…

Quantum Physics · Physics 2025-05-09 Kwok-Ho Ng , Tingting Song , Zhiquan Liu

Weakly supervised nuclei segmentation is a critical problem for pathological image analysis and greatly benefits the community due to the significant reduction of labeling cost. Adopting point annotations, previous methods mostly rely on…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Weizhen Liu , Qian He , Xuming He

Accurate segmenting nuclei instances is a crucial step in computer-aided image analysis to extract rich features for cellular estimation and following diagnosis as well as treatment. While it still remains challenging because the wide…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Yanning Zhou , Omer Fahri Onder , Qi Dou , Efstratios Tsougenis , Hao Chen , Pheng-Ann Heng

Automated cervical nucleus segmentation based on deep learning can effectively improve the quantitative analysis of cervical cancer. However, accurate nuclei segmentation is still challenging. The classic U-net has not achieved satisfactory…

Image and Video Processing · Electrical Eng. & Systems 2019-11-13 Jie Zhao , Lei Dai , Mo Zhang , Fei Yu , Meng Li , Hongfeng Li , Wenjia Wang , Li Zhang

Fluorescence microscopy is an essential tool for the analysis of 3D subcellular structures in tissue. An important step in the characterization of tissue involves nuclei segmentation. In this paper, a two-stage method for segmentation of…

Image and Video Processing · Electrical Eng. & Systems 2020-01-10 David Joon Ho , Shuo Han , Chichen Fu , Paul Salama , Kenneth W. Dunn , Edward J. Delp

Identify the cells' nuclei is the important point for most medical analyses. To assist doctors finding the accurate cell' nuclei location automatically is highly demanded in the clinical practice. Recently, fully convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Tianyang Zhang , Rui Ma

Semantic segmentation of electron microscopy (EM) is an essential step to efficiently obtain reliable morphological statistics. Despite the great success achieved using deep convolutional neural networks (CNNs), they still produce coarse…

Computer Vision and Pattern Recognition · Computer Science 2021-01-11 Zhimin Yuan , Xiaofen Ma , Jiajin Yi , Zhengrong Luo , Jialin Peng

Image segmentation plays an essential role in nuclei image analysis. Recently, the segment anything model has made a significant breakthrough in such tasks. However, the current model exists two major issues for cell segmentation: (1) the…

Image and Video Processing · Electrical Eng. & Systems 2023-08-24 Qing Xu , Wenwei Kuang , Zeyu Zhang , Xueyao Bao , Haoran Chen , Wenting Duan

Semantic image segmentation is a principal problem in computer vision, where the aim is to correctly classify each individual pixel of an image into a semantic label. Its widespread use in many areas, including medical imaging and…

Computer Vision and Pattern Recognition · Computer Science 2016-08-16 Vladimir Nekrasov , Janghoon Ju , Jaesik Choi

Semi-supervised segmentation methods have demonstrated promising results in natural scenarios, providing a solution to reduce dependency on manual annotation. However, these methods face significant challenges when directly applied to…

Computer Vision and Pattern Recognition · Computer Science 2024-02-08 Ye Zhang , Ziyue Wang , Yifeng Wang , Hao Bian , Linghan Cai , Hengrui Li , Lingbo Zhang , Yongbing Zhang

Nuclei instance segmentation in histopathological images is of great importance for biological analysis and cancer diagnosis but remains challenging for two reasons. (1) Similar visual presentation of intranuclear and extranuclear regions…

Computer Vision and Pattern Recognition · Computer Science 2024-02-12 Ye Zhang , Linghan Cai , Ziyue Wang , Yongbing Zhang

A common approach for moving objects segmentation in a scene is to perform a background subtraction. Several methods have been proposed in this domain. However, they lack the ability of handling various difficult scenarios such as…

Computer Vision and Pattern Recognition · Computer Science 2018-08-06 Long Ang Lim , Hacer Yalim Keles

Pathological diagnosis is the gold standard for tumor diagnosis, and nucleus instance segmentation is a key step in digital pathology analysis and pathological diagnosis. However, the computational efficiency of the model and the treatment…

Image and Video Processing · Electrical Eng. & Systems 2025-05-09 Shengchun Xiong , Xiangru Li , Yunpeng Zhong , Wanfen Peng

Every year millions of people die due to disease of Cancer. Due to its invasive nature it is very complex to cure even in primary stages. Hence, only method to survive this disease completely is via forecasting by analyzing the early…

Computer Vision and Pattern Recognition · Computer Science 2018-08-24 Shivam Singh , Stuti Pathak

There has been exploding interest in embracing Transformer-based architectures for medical image segmentation. However, the lack of large-scale annotated medical datasets make achieving performances equivalent to those in natural images…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Saikat Roy , Gregor Koehler , Constantin Ulrich , Michael Baumgartner , Jens Petersen , Fabian Isensee , Paul F. Jaeger , Klaus Maier-Hein