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Engineering system design, viewed as a decision-making process, faces challenges due to complexity and uncertainty. In this paper, we present a framework proposing the use of the Deep Q-learning algorithm to optimize the design of…

Machine Learning · Computer Science 2024-01-01 Ramin Giahi , Cameron A. MacKenzie , Reyhaneh Bijari

Optimizing the properties of molecules (materials or drugs) for stronger toughness, lower toxicity, or better bioavailability has been a long-standing challenge. In this context, we propose a molecular optimization framework called Q-Drug…

Quantum Physics · Physics 2023-08-28 Zhaoping Xiong , Xiaopeng Cui , Xinyuan Lin , Feixiao Ren , Bowen Liu , Yunting Li , Manhong Yung , Nan Qiao

Machine learning (ML) and deep learning (DL) techniques have been widely applied to analyze electroencephalography (EEG) signals for disease diagnosis and brain-computer interfaces (BCI). The integration of multimodal data has been shown to…

Signal Processing · Electrical Eng. & Systems 2025-01-16 Siqi Zhao , Wangyang Li , Xiru Wang , Stevie Foglia , Hongzhao Tan , Bohan Zhang , Ameer Hamoodi , Aimee Nelson , Zhen Gao

Introduction: Digital products increasingly reshape industries, influencing human behavior and decision-making. However, the software development teams developing these systems often lack diversity, which may lead to designs that overlook…

Artificial Intelligence (AI) and Machine-Learning (ML) models have been increasingly used in medical products, such as medical device software. General considerations on the statistical aspects for the evaluation of AI/ML-enabled medical…

Methodology · Statistics 2023-03-10 Feiming Chen , Hong Laura Lu , Arianna Simonetti

Despite ongoing advancements in quantum computing, businesses are still faced with the problem to decide if they would benefit from investing into this novel technology for building a business critical application. This uncertainty is not…

Software Engineering · Computer Science 2021-04-20 Janardan Misra , Vikrant Kaulgud , Rupesh Kaslay , Sanjay Podder

A new type of experiment with joint considerations of quantitative and sequence factors is recently drawing much attention in medical science, bio-engineering, and many other disciplines. The input spaces of such experiments are…

Methodology · Statistics 2025-02-06 Yaping Wang , Sixu Liu , Qian Xiao

Background: Clinical prediction models are increasingly used to inform healthcare decisions, but determining the minimum sample size for their development remains a critical and unresolved challenge. Inadequate sample sizes can lead to…

Machine Learning · Computer Science 2026-03-02 Diana Shamsutdinova , Felix Zimmer , Oyebayo Ridwan Olaniran , Sarah Markham , Daniel Stahl , Gordon Forbes , Ewan Carr

The ongoing progress in quantum technologies has fueled a sustained exploration of their potential applications across various domains. One particularly promising field is quantitative finance, where a central challenge is the pricing of…

Quantum Physics · Physics 2025-10-23 Fernando Alonso , Álvaro Leitao , Carlos Vázquez

Resiliency has garnered attention in the management of critical infrastructure as a metric of system performance, but there are significant roadblocks to its implementation in a realistic decision-making framework. Contrasted to risk and…

Systems and Control · Electrical Eng. & Systems 2026-01-08 Vincent P. Paglioni , Graeme Troxell , Aaron Brown , Steve Conrad , Mazdak Arabi

Machine learning has been increasingly utilized in the field of biomedical research to accelerate the drug discovery process. In recent years, the emergence of quantum computing has been followed by extensive exploration of quantum machine…

Research in software engineering is essential for improving development practices, leading to reliable and secure software. Leveraging the principles of quantum physics, quantum computing has emerged as a new computational paradigm that…

Software Engineering · Computer Science 2025-02-14 Ashis Kumar Mandal , Md Nadim , Chanchal K. Roy , Banani Roy , Kevin A. Schneider

When prospectively developing a new clinical prediction model (CPM), fixed sample size calculations are typically conducted before data collection based on sensible assumptions. But if the assumptions are inaccurate the actual sample size…

Aligning software-related activities with corporate strategies and goals is increasingly important for several reasons such as increasing the customer satisfaction in software-based products and services. Several approaches have been…

Software Engineering · Computer Science 2013-11-08 Jürgen Münch , Fabian Fagerholm , Petri Kettunen , Max Pagels , Jari Partanen

An early phase clinical trial is the first step in evaluating the effects in humans of a potential new anti-disease agent or combination of agents. Usually called "phase I" or "phase I/II" trials, these experiments typically have the…

Methodology · Statistics 2010-12-01 Peter F. Thall

The goal of a traditional Markov decision process (MDP) is to maximize expected cumulative reward over a defined horizon (possibly infinite). In many applications, however, a decision maker may be interested in optimizing a specific…

Artificial Intelligence · Computer Science 2025-10-16 Xiaocheng Li , Huaiyang Zhong , Margaret L. Brandeau

Categorization is necessary for many decision making tasks. However, the categorization process may interfere the decision making result and the law of total probability can be violated in some situations. To predict the interference effect…

Artificial Intelligence · Computer Science 2017-03-09 Zichang He , Wen Jiang

Quantum Computing (QC) is undergoing a high rate of development, investment and research devoted to its improvement.However, there is little consensus in the industry and wider literature as to what improvement might consist of beyond…

Quantum Physics · Physics 2024-05-15 Jessica Park , Susan Stepney , Irene D'Amico

Human-robot interactive decision-making is increasingly becoming ubiquitous, and trust is an influential factor in determining the reliance on autonomy. However, it is not reasonable to trust systems that are beyond our comprehension, and…

Machine Learning · Computer Science 2021-08-16 Daoming Lyu , Fangkai Yang , Hugh Kwon , Wen Dong , Levent Yilmaz , Bo Liu

In source memory studies, a decision-maker is concerned with identifying the context in which a given episodic experience occurred. A common paradigm for studying source memory is the `three-list' experimental paradigm, where a subject…

Quantum Physics · Physics 2018-08-24 Jan Broekaert , Jerome Busemeyer