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This article explores the critical role of statistical analysis in precision medicine. It discusses how personalized healthcare is enhanced by statistical methods that interpret complex, multidimensional datasets, focusing on predictive…

Machine Learning · Computer Science 2024-01-17 Xiaofei Chen

Cognitive diagnosis has been developed for decades as an effective measurement tool to evaluate human cognitive status such as ability level and knowledge mastery. It has been applied to a wide range of fields including education, sport,…

Artificial Intelligence · Computer Science 2024-07-09 Fei Wang , Weibo Gao , Qi Liu , Jiatong Li , Guanhao Zhao , Zheng Zhang , Zhenya Huang , Mengxiao Zhu , Shijin Wang , Wei Tong , Enhong Chen

Although deep learning (DL) has already become a state-of-the-art technology for various data processing tasks, data security and computational overload problems often arise due to their high data and computational power dependency. To…

Quantum Physics · Physics 2022-04-08 Yunseok Kwak , Won Joon Yun , Jae Pyoung Kim , Hyunhee Cho , Minseok Choi , Soyi Jung , Joongheon Kim

Supply Chain Management requires addressing a variety of complex decision-making challenges, from sourcing strategies to planning and execution. Over the last few decades, advances in computation and information technologies have enabled…

Artificial Intelligence · Computer Science 2025-07-30 David Simchi-Levi , Konstantina Mellou , Ishai Menache , Jeevan Pathuri

Design studies aim to create visualization solutions for real-world problems of different application domains. Recently, the emergence of large language models (LLMs) has introduced new opportunities to enhance the design study process,…

Human-Computer Interaction · Computer Science 2025-08-14 Shaolun Ruan , Rui Sheng , Xiaolin Wen , Jiachen Wang , Tianyi Zhang , Yong Wang , Tim Dwyer , Jiannan Li

As a compact representation of joint probability distributions over a dependence graph of random variables, and a tool for modelling and reasoning in the presence of uncertainty, Bayesian networks are of great importance for artificial…

Quantum Physics · Physics 2020-10-06 Michael de Oliveira , Luis Soares Barbosa

Most protocols for the high-throughput directed evolution of enzymes rely on random encapsulation to link phenotype and genotype. In order to optimize these approaches, or compare one to another, one needs a measure of their performance at…

Populations and Evolution · Quantitative Biology 2018-11-14 Adèle Dramé-Maigné , Anton Zadorin , Iaroslava Golovkova , Yannick Rondelez

The traditional more-is-better dose selection paradigm, developed based on cytotoxic chemotherapeutics, is often problematic When applied to the development of novel molecularly targeted agents (e.g., kinase inhibitors, monoclonal…

Methodology · Statistics 2022-11-04 Liyun Jiang , Ying Yuan

Data-driven methods for establishing quantum optimal control (QOC) using time-dependent control pulses tailored to specific quantum dynamical systems and desired control objectives are critical for many emerging quantum technologies. We…

Quantum Physics · Physics 2021-03-29 Andy Goldschmidt , Eurika Kaiser , Jonathan L. Dubois , Steven L. Brunton , J. Nathan Kutz

Quantum Monte Carlo (QMC) methods have received considerable attention over the last decades due to their great promise for providing a direct solution to the many-body Schrodinger equation in electronic systems. Thanks to their low scaling…

Chemical Physics · Physics 2013-03-28 M. A. Morales , J. McMinis , B. K. Clark , J. Kim , G. Scuseria

Identifying and discovering drug-target interactions(DTIs) are vital steps in drug discovery and development. They play a crucial role in assisting scientists in finding new drugs and accelerating the drug development process. Recently,…

Quantitative Methods · Quantitative Biology 2023-11-15 Wenting Ye , Chen Li , Yang Xie , Wen Zhang , Hong-Yu Zhang , Bowen Wang , Debo Cheng , Zaiwen Feng

Computational prediction of enzyme mechanism and protein function requires accurate physics-based models and suitable sampling. We discuss recent advances in large-scale quantum mechanical (QM) modeling of biochemical systems that have…

Chemical Physics · Physics 2021-05-28 Vyshnavi Vennelakanti , Azadeh Nazemi , Rimsha Mehmood , Adam H. Steeves , Heather J. Kulik

In the context of clinical research, computational models have received increasing attention over the past decades. In this systematic review, we aimed to provide an overview of the role of so-called in silico clinical trials (ISCTs) in…

The financial sector is anticipated to be one of the first industries to benefit from the increased computational power of quantum computers, in areas such as portfolio optimisation and risk management to financial derivative pricing.…

Quantum Physics · Physics 2023-11-10 Nicholas Bornman

Online controlled experimentation is widely adopted for evaluating new features in the rapid development cycle for web products and mobile applications. Measurement of the overall experiment sample is a common practice to quantify the…

Human-Computer Interaction · Computer Science 2022-01-27 Zhenyu Zhao , Yan He , Miao Chen

Quantum Molecular Dynamics (QMD) calculations are used to study the expansion phase in central collisions between heavy nuclei. The final state of such a reaction can be understood as the result of a entropy conserving expansion starting…

Nuclear Theory · Physics 2007-05-23 Jens Konopka , Horst Stoecker , Walter Greiner

Molecular dynamics simulation is now a widespread approach for understanding complex systems on the atomistic scale. It finds applications from physics and chemistry to engineering, life and medical science. In the last decade, the approach…

Computational Physics · Physics 2021-04-28 Shunzhou Wan , Robert C. Sinclair , Peter V. Coveney

Device-independent (DI) quantum secret sharing (QSS) can relax the security assumptions about the devices' internal workings and provide QSS the highest level of security in theory. The original DI QSS protocol proved its correctness and…

Quantum Physics · Physics 2024-10-11 Qi Zhang , Wei Zhong , Ming-Ming Du , Shu-Ting Shen , Xi-Yun Li , An-Lei Zhang , Lan Zhou , Yu-Bo Sheng

In the wake of relentless digital transformation, data-driven solutions are emerging as powerful tools to address multifarious industrial tasks such as forecasting, anomaly detection, planning, and even complex decision-making. Although…

Artificial Intelligence · Computer Science 2023-10-18 Xu Yang , Xiao Yang , Weiqing Liu , Jinhui Li , Peng Yu , Zeqi Ye , Jiang Bian

We describe the current state and future plans for a set of tools for scientific data management (SDM) designed to support scientific transparency and reproducible research. SDM has been in active use at our MRI Center for more than two…

Quantitative Methods · Quantitative Biology 2015-02-25 B. A. Wandell , A. Rokem , L. M. Perry , G. Schaefer , R. F. Dougherty
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