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Unsupervised deep learning is a promising method in brain MRI registration to reduce the reliance on anatomical labels, while still achieving anatomically accurate transformations. For the Learn2Reg2024 LUMIR challenge, we propose…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Lukas Förner , Kartikay Tehlan , Thomas Wendler

Affine image registration is a cornerstone of medical image analysis. While classical algorithms can achieve excellent accuracy, they solve a time-consuming optimization for every image pair. Deep-learning (DL) methods learn a function that…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Malte Hoffmann , Andrew Hoopes , Douglas N. Greve , Bruce Fischl , Adrian V. Dalca

As in other areas of medical image analysis, e.g. semantic segmentation, deep learning is currently driving the development of new approaches for image registration. Multi-scale encoder-decoder network architectures achieve state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Lasse Hansen , Mattias P. Heinrich

We propose a registration algorithm for 2D CT/MRI medical images with a new unsupervised end-to-end strategy using convolutional neural networks. The contributions of our algorithm are threefold: (1) We transplant traditional image…

Computer Vision and Pattern Recognition · Computer Science 2018-01-23 Siyuan Shan , Wen Yan , Xiaoqing Guo , Eric I-Chao Chang , Yubo Fan , Yan Xu

Deformable image registration, estimating the spatial transformation between different images, is an important task in medical imaging. Many previous studies have used learning-based methods for multi-stage registration to perform 3D image…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Jian-Qing Zheng , Ziyang Wang , Baoru Huang , Ngee Han Lim , Tonia Vincent , Bartlomiej W. Papiez

We present a novel algorithm for the registration of pulmonary CT scans. Our method is designed for large respiratory motion by integrating sparse keypoint correspondences into a dense continuous optimization framework. The detection of…

Computer Vision and Pattern Recognition · Computer Science 2018-07-03 Jan Rühaak , Thomas Polzin , Stefan Heldmann , Ivor J. A. Simpson , Heinz Handels , Jan Modersitzki , Mattias P. Heinrich

We present a fast learning-based algorithm for deformable, pairwise 3D medical image registration. Current registration methods optimize an objective function independently for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

Recent deep learning-based methods for medical image registration achieve results that are competitive with conventional optimization algorithms at reduced run times. However, deep neural networks generally require plenty of labeled…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Alexander Bigalke , Lasse Hansen , Mattias P. Heinrich

Current approaches for deformable medical image registration often struggle to fulfill all of the following criteria: versatile applicability, small computation or training times, and the being able to estimate large deformations.…

Image and Video Processing · Electrical Eng. & Systems 2021-12-07 Hanna Siebert , Lasse Hansen , Mattias P. Heinrich

Advanced navigation techniques in image-guided interventions and surgical robotics require the rapid and precise alignment of 3D preoperative volumes (e.g., CT, MRI) to 2D intraoperative images (e.g., X-ray fluoroscopy). However, existing…

Complicated image registration is a key issue in medical image analysis, and deep learning-based methods have achieved better results than traditional methods. The methods include ConvNet-based and Transformer-based methods. Although…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Runshi Zhang , Hao Mo , Junchen Wang , Bimeng Jie , Yang He , Nenghao Jin , Liang Zhu

We present HyperMorph, a learning-based strategy for deformable image registration that removes the need to tune important registration hyperparameters during training. Classical registration methods solve an optimization problem to find a…

Computer Vision and Pattern Recognition · Computer Science 2021-05-06 Andrew Hoopes , Malte Hoffmann , Bruce Fischl , John Guttag , Adrian V. Dalca

Medical image registration drives quantitative analysis across organs, modalities, and patient populations. Recent deep learning methods often combine low-level "trend-driven" computational blocks from computer vision, such as large-kernel…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Bailiang Jian , Jiazhen Pan , Rohit Jena , Morteza Ghahremani , Hongwei Bran Li , Daniel Rueckert , Christian Wachinger , Benedikt Wiestler

Deformable medical image registration is an essential task in computer-assisted interventions. This problem is particularly relevant to oncological treatments, where precise image alignment is necessary for tracking tumor growth, assessing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Stefano Fogarollo , Gregor Laimer , Reto Bale , Matthias Harders

Non-rigid cortical registration is an important and challenging task due to the geometric complexity of the human cortex and the high degree of inter-subject variability. A conventional solution is to use a spherical representation of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-28 Jieyu Cheng , Adrian V. Dalca , Bruce Fischl , Lilla Zollei

The purpose of this study is to develop a deep learning based method that can automatically generate segmentations on cone-beam CT (CBCT) for head and neck online adaptive radiation therapy (ART), where expert-drawn contours in planning CT…

Medical Physics · Physics 2021-02-02 Xiao Liang , Howard Morgan , Dan Nguyen , Steve Jiang

Registration is a fundamental task in medical robotics and is often a crucial step for many downstream tasks such as motion analysis, intra-operative tracking and image segmentation. Popular registration methods such as ANTs and NiftyReg…

Computer Vision and Pattern Recognition · Computer Science 2021-03-26 Wentao Zhu , Yufang Huang , Daguang Xu , Zhen Qian , Wei Fan , Xiaohui Xie

In the last decade, convolutional neural networks (ConvNets) have been a major focus of research in medical image analysis. However, the performances of ConvNets may be limited by a lack of explicit consideration of the long-range spatial…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Junyu Chen , Eric C. Frey , Yufan He , William P. Segars , Ye Li , Yong Du

Deformable medical image registration is a fundamental task in medical image analysis with applications in disease diagnosis, treatment planning, and image-guided interventions. Despite significant advances in deep learning based…

Machine Learning · Computer Science 2026-02-10 Muhammad Zafar Iqbal , Ghazanfar Farooq Siddiqui , Anwar Ul Haq , Imran Razzak