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Quantum computers offer a promising route to tackling problems that are classically intractable such as in prime-factorization, solving large-scale linear algebra and simulating complex quantum systems, but potentially require…

We make the case that variational algorithm ansatzes for near-term quantum computing are well-suited for the quantum circuit cutting strategy. Previous demonstrations of circuit cutting focused on the exponential execution and…

Quantum Physics · Physics 2024-12-25 Zirui Li , Minghao Guo , Mayank Barad , Wei Tang , Eddy Z. Zhang , Yipeng Huang

Quantum simulation of chemical systems is one of the most promising near-term applications of quantum computers. The variational quantum eigensolver, a leading algorithm for molecular simulations on quantum hardware, has a serious…

Quantum Physics · Physics 2019-07-16 Harper R. Grimsley , Sophia E. Economou , Edwin Barnes , Nicholas J. Mayhall

Achieving quantum speedups in practical tasks remains challenging for current noisy intermediate-scale quantum (NISQ) devices. These devices always encounter significant obstacles such as inevitable physical errors and the limited…

Quantum Physics · Physics 2024-08-28 Riki Toshio , Yutaro Akahoshi , Jun Fujisaki , Hirotaka Oshima , Shintaro Sato , Keisuke Fujii

Variational quantum algorithms (VQAs) have the potential to demonstrate quantum utility on near-term quantum computers. However, these algorithms often get executed on the highest-fidelity qubits and computers to achieve the best…

Quantum Physics · Physics 2025-10-13 Yuqian Huo , David Quiroga , Anastasios Kyrillidis , Tirthak Patel

The quantum approximate optimisation algorithm (QAOA) is at the core of many scenarios that aim to combine the power of quantum computers and classical high-performance computing appliances for combinatorial optimisation. Several obstacles…

Quantum Physics · Physics 2026-02-26 Simon Thelen , Hila Safi , Wolfgang Mauerer

The Quantum Approximate Optimization Algorithm (QAOA) adopts a hybrid quantum-classical approach to find approximate solutions to variational optimization problems. In fact, it relies on a classical subroutine to optimize the parameters of…

Quantum Physics · Physics 2023-07-31 Simone Tibaldi , Davide Vodola , Edoardo Tignone , Elisa Ercolessi

Conformation generation, also known as molecular unfolding (MU), is a crucial step in structure-based drug design, remaining a challenging combinatorial optimization problem. Quantum annealing (QA) has shown great potential for solving…

Classical simulation of molecular systems is limited by exponential scaling, a hurdle quantum algorithms like Variational Quantum Eigensolvers (VQEs) aim to overcome. Although ADAPT-VQE enhances VQEs by dynamically building ans\"atze, it…

Quantum Physics · Physics 2025-06-23 Tatiana A. Bespalova , Oumaya Ladhari , Guido Masella

The quantum approximate optimisation ansatz (QAOA) is one of the flagship algorithms used to tackle combinatorial optimisation on graphs problems using a quantum computer, and is considered a strong candidate for early fault-tolerant…

Quantum Physics · Physics 2025-06-24 Yann Beaujeault-Taudière

Quantum variational optimization has been posed as an alternative to solve optimization problems faster and at a larger scale than what classical methods allow. In this paper we study systematically the role of entanglement, the structure…

Quantum Physics · Physics 2021-12-30 Pablo Díez-Valle , Diego Porras , Juan José García-Ripoll

The variational quantum eigensolver (VQE) is an algorithm for finding the ground states of a given Hamiltonian. Its application to binary-formulated combinatorial optimization (CO) has been widely studied in recent years. However, typical…

Quantum Physics · Physics 2025-08-08 Ningyi Xie , Xinwei Lee , Tiejin Chen , Yoshiyuki Saito , Nobuyoshi Asai , Dongsheng Cai

The Quantum Approximate Optimization Algorithm (QAOA) is a promising algorithm for solving combinatorial optimization problems (COPs), with performance governed by variational parameters $\{\gamma_i, \beta_i\}_{i=0}^{p-1}$. While most prior…

Quantum Physics · Physics 2025-08-07 J. A. Montanez-Barrera , Kristel Michielsen

Quantum computing offers a potential for algorithmic speedups for applications, such as large-scale simulations in chemistry and physics. However, these speedups must yield results that are sufficiently accurate to predict realistic…

Quantum Physics · Physics 2025-01-15 Meenambika Gowrishankar , Daniel Claudino , Jerimiah Wright , Travis Humble

The Quantum Alternating Operator Ansatz (QAOA+) is one of the Variational Quantum Algorithm (VQA) specifically developed to tackle combinatorial optimization problems by exploring the feasible space in search of a target solution. For…

Quantum Physics · Physics 2024-01-12 Sha-Sha Wang , Hai-Ling Liu , Yong-Mei Li , Fei Gao , Su-Juan Qin , Qiao-Yan Wen

The Variational Quantum Eigensolver (VQE) is one the most perspective algorithms for simulation of quantum many body physics that have recently attached a lot of attention and believed would be practical for implementation on the near term…

Quantum Physics · Physics 2021-05-03 Belozerova Polina , Shangareev Arthur , Zotov Yuriy , Yung Manhong , lv Dingshun

The encoding of classical to quantum data mapping through trigonometric functions within arithmetic-based quantum computation algorithms leads to the exploitation of multivariate distributions. The studied variational quantum gate learning…

Quantum Physics · Physics 2025-11-12 Ziqing Guo , Jan Balewski , Wenshuo Hu , Alex Khan , Ziwen Pan

Quantum computers currently rely on a hybrid quantum-classical approach known as Variational Quantum Algorithms (VQAs) to solve problems. Still, there are several challenges with VQAs on the classical computing side: it corresponds to a…

Variational quantum algorithms (VQAs) are prominent candidates for near-term quantum advantage but lack rigorous guarantees of convergence and generalization. By contrast, quantum phase estimation (QPE) provides provable performance under…

Quantum Physics · Physics 2025-10-09 Tuyen Nguyen , Mária Kieferová

The presence of stochastic elements in combinatorial optimization problems makes them particularly challenging, as such problems quickly become intractable for classical computers even at relatively small sizes. In this work, we propose a…

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