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In group testing, the task is to determine the distinguished members of a set of objects L by asking subset queries of the form ``does the subset Q of L contain a distinguished object?'' The primary biological application of group testing…

Combinatorics · Mathematics 2008-02-03 Emanuel Knill , S. Muthukrishnan

We develop a statistical model for the testing of disease prevalence in a population. The model assumes a binary test result, positive or negative, but allows for biases in sample selection and both type I (false positive) and type II…

Applications · Statistics 2021-12-28 Lucas Böttcher , Maria R. D'Orsogna , Tom Chou

Grouping patients meaningfully can give insights about the different types of patients, their needs, and the priorities. Finding groups that are meaningful is however very challenging as background knowledge is often required to determine…

Databases · Computer Science 2019-04-04 Seyed Amin Tabatabaei , Xixi Lu , Mark Hoogendoorn , Hajo A. Reijers

We explore the problem of deriving a posteriori probabilities of being defective for the members of a population in the non-adaptive group testing framework. Both noiseless and noisy testing models are addressed. The technique, which relies…

Information Theory · Computer Science 2021-02-11 Gianluigi Liva , Enrico Paolini , Marco Chiani

Genome-wide association analysis has generated much discussion about how to preserve power to detect signals despite the detrimental effect of multiple testing on power. We develop a weighted multiple testing procedure that facilitates the…

Statistics Theory · Mathematics 2007-06-13 Kathryn Roeder , Bernie Devlin , Larry Wasserman

Distant supervision based methods for entity and relation extraction have received increasing popularity due to the fact that these methods require light human annotation efforts. In this paper, we consider the problem of \textit{shifted…

Computation and Language · Computer Science 2020-04-22 Daoyuan Chen , Yaliang Li , Kai Lei , Ying Shen

The first part of the paper presents a review of the gold-standard testing protocol for Covid-19, real-time, reverse transcriptase PCR, and its properties and associated measurement data such as amplification curves that can guide the…

Quantitative Methods · Quantitative Biology 2021-06-08 Ryan Gabrys , Srilakshmi Pattabiraman , Vishal Rana , João Ribeiro , Mahdi Cheraghchi , Venkatesan Guruswami , Olgica Milenkovic

In comparison with individual testing, group testing (also known as pooled testing) is more efficient in reducing the number of tests and potentially leading to tremendous cost reduction. As indicated in the recent article posted on the US…

Populations and Evolution · Quantitative Biology 2021-06-16 Yi-Jheng Lin , Che-Hao Yu , Tzu-Hsuan Liu , Cheng-Shang Chang , Wen-Tsuen Chen

Consider a finite population of $N$ items, where item $i$ has a probability $p_i$ to be defective. The goal is to identify all items by means of group testing. This is the generalized group testing problem (hereafter GGTP). In the case of…

Other Statistics · Statistics 2020-02-28 Yaakov Malinovsky

Background: When planning a cluster randomized trial, evaluators often have access to an enumerated cohort representing the target population of clusters. Practicalities of conducting the trial, such as the need to oversample clusters with…

Methodology · Statistics 2024-09-19 Sarah E. Robertson , Jon A. Steingrimsson , Issa J. Dahabreh

Entanglement plays an indispensable role in numerous quantum information and quantum computation tasks, underscoring the need for efficiently verifying entangled states. In recent years, quantum state verification has received increasing…

Quantum Physics · Physics 2025-12-15 Lan Zhang , Yinfei Li , Ye-Chao Liu , Jiangwei Shang

A simple and common type of medical research involves the comparison of one treatment against another. The logical aim should be both to establish which treatment is superior and the strength of evidence supporting this conclusion, a task…

Methodology · Statistics 2022-12-08 Nicholas Adams

In the group testing problem, the goal is to identify a subset of defective items within a larger set of items based on tests whose outcomes indicate whether any defective item is present. This problem is relevant in areas such as medical…

Information Theory · Computer Science 2022-09-28 Nelvin Tan , Way Tan , Jonathan Scarlett

We study the problem of identifying defective units in a finite population of \( n \) units, where each unit \( i \) is independently defective with known probability \( p_i \). This setting is referred to as the \emph{Generalized Group…

Statistics Theory · Mathematics 2025-06-23 Yaakov Malinovsky , Viktor Skorniakov

For testing the statistical significance of a treatment effect, we usually compare between two parts of a population, one is exposed to the treatment, and the other is not exposed to it. Standard parametric and nonparametric two-sample…

Computation · Statistics 2012-11-02 Bikram Karmakar , Kumaresh Dhara , Kushal Kumar Dey , Analabha Basu , Anil Ghosh

Network data are increasingly collected along with other variables of interest. Our motivation is drawn from neurophysiology studies measuring brain connectivity networks for a sample of individuals along with their membership to a low or…

Methodology · Statistics 2018-09-11 Daniele Durante , David B. Dunson

In this work we study the problem of measuring the fairness of a machine learning model under noisy information. Focusing on group fairness metrics, we investigate the particular but common situation when the evaluation requires controlling…

Machine Learning · Computer Science 2021-05-24 Flavien Prost , Pranjal Awasthi , Nick Blumm , Aditee Kumthekar , Trevor Potter , Li Wei , Xuezhi Wang , Ed H. Chi , Jilin Chen , Alex Beutel

In order to identify the infected individuals of a population, their samples are divided in equally sized groups called pools and a single laboratory test is applied to each pool. Individuals whose samples belong to pools that test negative…

Statistics Theory · Mathematics 2021-10-06 Inés Armendáriz , Pablo A. Ferrari , Daniel Fraiman , José M. Martínez , Silvina Ponce Dawson

We propose a mathematical model based on probability theory to optimize COVID-19 testing by a multi-step batch testing approach with variable batch sizes. This model and simulation tool dramatically increase the efficiency and efficacy of…

Methodology · Statistics 2021-01-11 Hongshik Ahn , Haoran Jiang , Xiaolin Li

When an individual reports a negative interaction with some system, how can their personal experience be contextualized within broader patterns of system behavior? We study the reporting database problem, where individual reports of adverse…

Computers and Society · Computer Science 2025-05-30 Jessica Dai , Paula Gradu , Inioluwa Deborah Raji , Benjamin Recht