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Sample pooling consists in combining samples from multiple individuals into a single pool that is then tested using a unique test-kit. A positive test means that at least one individual within the pool is infected. Here, we propose an…

Quantitative Methods · Quantitative Biology 2021-03-18 Vincent Brault , Bastien Mallein , Jean-Francois Rupprecht

In group sequential designs, where several data looks are conducted for early stopping, we generally assume the vector of test statistics from the sequential analyses follows (at least approximately or asymptotially) a multivariate normal…

Statistics Theory · Mathematics 2024-04-22 Long-Hao Xu , Tobias Mütze , Frank Konietschke , Tim Friede

The group testing approach that achieves significant cost reduction over the individual testing approach has received a lot of interest lately for massive testing of COVID-19. Many studies simply assume samples mixed in a group are…

Methodology · Statistics 2021-11-12 Yi-Jheng Lin , Che-Hao Yu , Tzu-Hsuan Liu , Cheng-Shang Chang , Wen-Tsuen Chen

We investigate the problems of identity and closeness testing over a discrete population from random samples. Our goal is to develop efficient testers while guaranteeing Differential Privacy to the individuals of the population. We describe…

Machine Learning · Computer Science 2017-07-19 Maryam Aliakbarpour , Ilias Diakonikolas , Ronitt Rubinfeld

Bayesian hypothesis testing and minimax hypothesis testing represent extreme instances of detection in which the prior probabilities of the hypotheses are either completely and precisely known, or are completely unknown. Group minimax, also…

Information Theory · Computer Science 2013-07-25 Kush R. Varshney , Lav R. Varshney

Repeated asymptomatic screening for SARS-CoV-2 promises to control spread of the virus but would require too many resources to implement at scale. Group testing is promising for screening more people with fewer test resources: multiple…

Populations and Evolution · Quantitative Biology 2020-11-18 Yifan Lin , Yuxuan Ren , Jingyuan Wan , Massey Cashore , Jiayue Wan , Yujia Zhang , Peter Frazier , Enlu Zhou

We consider sequential hypothesis testing based on observations which are received in groups of random size. The observations are assumed to be independent both within and between the groups. We assume that the group sizes are independent…

Methodology · Statistics 2021-10-11 Andrey Novikov , Xóchitl Itxel Popoca-Jiménez

Group testing is a well known search problem that consists in detecting the defective members of a set of objects O by performing tests on properly chosen subsets (pools) of the given set O. In classical group testing the goal is to find…

Data Structures and Algorithms · Computer Science 2016-06-13 Annalisa De Bonis

For large classes of group testing problems, we derive lower bounds for the probability that all significant items are uniquely identified using specially constructed random designs. These bounds allow us to optimize parameters of the…

Statistics Theory · Mathematics 2022-02-17 Jack Noonan , Anatoly Zhigljavsky

Count data and recurrent events in clinical trials, such as the number of lesions in magnetic resonance imaging in multiple sclerosis, the number of relapses in multiple sclerosis, the number of hospitalizations in heart failure, and the…

Applications · Statistics 2019-03-07 Tobias Mütze , Ekkehard Glimm , Heinz Schmidli , Tim Friede

In recent years, network coding has been investigated as a method to obtain improvements in wireless networks. A typical assumption of previous work is that relay nodes performing network coding can decode the messages from sources…

Information Theory · Computer Science 2007-07-13 Sichao Yang , Ralf Koetter

Understanding how information can efficiently spread in distributed systems under noisy communications is a fundamental question in both biological research and artificial system design. When agents are able to control whom they interact…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-11-11 Niccolò D'Archivio , Amos Korman , Emanuele Natale , Robin Vacus

Group testing is a long studied problem in combinatorics: A small set of $r$ ill people should be identified out of the whole ($n$ people) by using only queries (tests) of the form "Does set X contain an ill human?". In this paper we…

Data Structures and Algorithms · Computer Science 2008-04-29 Ely Porat , Amir Rothschild

Suppose that we are interested in the comparison of two independent categorical variables. Suppose also that the population is divided into subpopulations or groups. Notice that the distribution of the target variable may vary across…

Methodology · Statistics 2024-05-08 M. V. Alba-Fernández , M. D. Jiménez--Gamero , F. J. Ariza-López

In this paper, we consider the problem of noiseless non-adaptive probabilistic group testing, in which the goal is high-probability recovery of the defective set. We show that in the case of $n$ items among which $k$ are defective, the…

Information Theory · Computer Science 2021-07-30 Wei Heng Bay , Eric Price , Jonathan Scarlett

We consider the group testing problem, in the case where the items are defective independently but with non-constant probability. We introduce and analyse an algorithm to solve this problem by grouping items together appropriately. We give…

Information Theory · Computer Science 2015-02-04 Tom Kealy , Oliver Johnson , Robert Piechocki

Motivated by testing for pathogenic diseases we consider a new nonadaptive group testing problem for which: (1) positives occur within a burst, capturing the fact that infected test subjects often come in clusters, and (2) that the test…

Information Theory · Computer Science 2023-04-05 Yun-Han Li , Ryan Gabrys , Jin Sima , Ilan Shomorony , Olgica Milenkovic

Machine learning in the context of noise is a challenging but practical setting to plenty of real-world applications. Most of the previous approaches in this area focus on the pairwise relation (casual or correlational relationship) with…

Machine Learning · Computer Science 2021-03-18 Qizhou Wang , Jiangchao Yao , Chen Gong , Tongliang Liu , Mingming Gong , Hongxia Yang , Bo Han

During the COVID-19 pandemic, many institutions such as universities and workplaces implemented testing regimens with every member of some population tested longitudinally, and those testing positive isolated for some time. Although the…

Methodology · Statistics 2023-04-19 Patrick M. Schnell , Matthew Wascher , Grzegorz A. Rempala

We consider a novel method to increase the reliability of COVID-19 virus or antibody tests by using specially designed pooled testings. Instead of testing nasal swab or blood samples from individual persons, we propose to test mixtures of…

Quantitative Methods · Quantitative Biology 2020-07-30 Jirong Yi , Myung Cho , Xiaodong Wu , Weiyu Xu , Raghu Mudumbai
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