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High-dimensional time series are common in many domains. Since human cognition is not optimized to work well in high-dimensional spaces, these areas could benefit from interpretable low-dimensional representations. However, most…

Machine Learning · Computer Science 2019-01-07 Vincent Fortuin , Matthias Hüser , Francesco Locatello , Heiko Strathmann , Gunnar Rätsch

Mechanistic interpretability focuses on reverse engineering the internal mechanisms learned by neural networks. We extend our focus and propose to mechanistically forward engineer using our framework based on Concept Bottleneck Models. In…

Machine Learning · Computer Science 2025-12-01 Angela van Sprang , Erman Acar , Willem Zuidema

Tackling pattern recognition problems in areas such as computer vision, bioinformatics, speech or text recognition is often done best by taking into account task-specific statistical relations between output variables. In structured…

Machine Learning · Statistics 2016-03-14 Rein Houthooft , Filip De Turck

Despite their impressive performance, contemporary neural networks often lack structural safeguards that promote stable learning and interpretable behavior. In this work, we introduce a reformulation of layer-level transformations that…

Machine Learning · Computer Science 2025-08-04 Saleh Nikooroo , Thomas Engel

With the advent of highly predictive but opaque deep learning models, it has become more important than ever to understand and explain the predictions of such models. Existing approaches define interpretability as the inverse of complexity…

Interpreting the inner function of neural networks is crucial for the trustworthy development and deployment of these black-box models. Prior interpretability methods focus on correlation-based measures to attribute model decisions to…

Machine Learning · Computer Science 2023-06-21 Ola Ahmad , Nicolas Bereux , Loïc Baret , Vahid Hashemi , Freddy Lecue

Deep time series models continue to improve predictive performance, yet their deployment remains limited by their black-box nature. In response, existing interpretability approaches in the field keep focusing on explaining the internal…

Machine Learning · Computer Science 2026-02-03 Giovanni De Felice , Riccardo D'Elia , Alberto Termine , Pietro Barbiero , Giuseppe Marra , Silvia Santini

As the use of deep learning techniques has grown across various fields over the past decade, complaints about the opaqueness of the black-box models have increased, resulting in an increased focus on transparency in deep learning models.…

Computation and Language · Computer Science 2024-03-19 Siwen Luo , Hamish Ivison , Caren Han , Josiah Poon

Protein language models are a powerful tool for learning protein representations through pre-training on vast protein sequence datasets. However, traditional protein language models lack explicit structural supervision, despite its…

Biomolecules · Quantitative Biology 2024-02-09 Zuobai Zhang , Jiarui Lu , Vijil Chenthamarakshan , Aurélie Lozano , Payel Das , Jian Tang

Data-driven modeling is an imperative tool in various industrial applications, including many applications in the sectors of aeronautics and commercial aviation. These models are in charge of providing key insights, such as which parameters…

Machine Learning · Computer Science 2022-03-28 Marios Kefalas , Juan de Santiago Rojo , Asteris Apostolidis , Dirk van den Herik , Bas van Stein , Thomas Bäck

As artificial intelligence is increasingly affecting all parts of society and life, there is growing recognition that human interpretability of machine learning models is important. It is often argued that accuracy or other similar…

Machine Learning · Statistics 2018-06-27 Kush R. Varshney , Prashant Khanduri , Pranay Sharma , Shan Zhang , Pramod K. Varshney

The use of models, even if efficient, must be accompanied by an understanding at all levels of the process that transforms data (upstream and downstream). Thus, needs increase to define the relationships between individual data and the…

Machine Learning · Statistics 2022-09-02 Dimitri Delcaillau , Antoine Ly , Alize Papp , Franck Vermet

The modeling and simulation of high-dimensional multiscale systems is a critical challenge across all areas of science and engineering. It is broadly believed that even with today's computer advances resolving all spatiotemporal scales…

Machine Learning · Statistics 2023-09-13 Emmanuel Menier , Sebastian Kaltenbach , Mouadh Yagoubi , Marc Schoenauer , Petros Koumoutsakos

Statistical and structural modeling represent two distinct approaches to data analysis. In this paper, we propose a set of novel methods for combining statistical and structural models for improved prediction and causal inference. Our first…

Econometrics · Economics 2020-06-11 Jiaming Mao , Jingzhi Xu

In many areas, we have well-founded insights about causal structure that would be useful to bring into our trained models while still allowing them to learn in a data-driven fashion. To achieve this, we present the new method of interchange…

Machine Learning · Computer Science 2022-07-22 Atticus Geiger , Zhengxuan Wu , Hanson Lu , Josh Rozner , Elisa Kreiss , Thomas Icard , Noah D. Goodman , Christopher Potts

I propose a model of systematic understanding, suitable for machine learning systems. On this account, an agent understands a property of a target system when it contains an adequate internal model that tracks real regularities, is coupled…

Artificial Intelligence · Computer Science 2026-04-07 David Peter Wallis Freeborn

Using machine learning, especially deep learning, to facilitate biological research is a fascinating research direction. However, in addition to the standard classification or regression problems, in bioinformatics, we often need to predict…

Quantitative Methods · Quantitative Biology 2020-08-31 Yu Li

Buildings account for a substantial portion of global energy consumption. Reducing buildings' energy usage primarily involves obtaining data from building systems and environment, which are instrumental in assessing and optimizing the…

Artificial Intelligence · Computer Science 2024-04-19 Miracle Aniakor , Vinicius V. Cogo , Pedro M. Ferreira

We conduct a systematic study of the approximation properties of Transformer for sequence modeling with long, sparse and complicated memory. We investigate the mechanisms through which different components of Transformer, such as the…

Machine Learning · Computer Science 2024-10-31 Mingze Wang , Weinan E

While the activations of neurons in deep neural networks usually do not have a simple human-understandable interpretation, sparse autoencoders (SAEs) can be used to transform these activations into a higher-dimensional latent space which…

Machine Learning · Computer Science 2025-08-07 Gonçalo Paulo , Alex Mallen , Caden Juang , Nora Belrose
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