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Colorectal and prostate cancers are the most common types of cancer in men worldwide. To diagnose colorectal and prostate cancer, a pathologist performs a histological analysis on needle biopsy samples. This manual process is time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2023-01-31 Remy Peyret , Duaa alSaeed , Fouad Khelifi , Nadia Al-Ghreimil , Heyam Al-Baity , Ahmed Bouridane

Flow cytometry mainly used for detecting the characteristics of a number of biochemical substances based on the expression of specific markers in cells. It is particularly useful for detecting membrane surface receptors, antigens, ions, or…

Machine Learning · Computer Science 2023-03-17 Yanhua Xu

Recently, there has been a resurgence of interest in rigorous algorithms for the inference of cancer progression from genomic data. The motivations are manifold: (i) growing NGS and single cell data from cancer patients, (ii) need for novel…

Machine Learning · Computer Science 2016-02-25 Daniele Ramazzotti

Cancer is a complex disease characterized by uncontrolled cell growth. T cell receptors (TCRs), crucial proteins in the immune system, play a key role in recognizing antigens, including those associated with cancer. Recent advancements in…

Machine Learning · Computer Science 2025-06-12 Taslim Murad , Prakash Chourasia , Sarwan Ali , Imdad Ullah Khan , Murray Patterson

Oral squamous cell carcinoma OSCC is a major global health burden, particularly in several regions across Asia, Africa, and South America, where it accounts for a significant proportion of cancer cases. Early detection dramatically improves…

This paper presents a complete Optical Character Recognition (OCR) system for camera captured image/graphics embedded textual documents for handheld devices. At first, text regions are extracted and skew corrected. Then, these regions are…

Computer Vision and Pattern Recognition · Computer Science 2011-09-16 Ayatullah Faruk Mollah , Nabamita Majumder , Subhadip Basu , Mita Nasipuri

Cell nuclei detection and fine-grained classification have been fundamental yet challenging problems in histopathology image analysis. Due to the nuclei tiny size, significant inter-/intra-class variances, as well as the inferior image…

Computer Vision and Pattern Recognition · Computer Science 2017-12-25 Yanning Zhou , Qi Dou , Hao Chen , Jing Qin , Pheng-Ann Heng

Cluster analysis aims at separating patients into phenotypically heterogenous groups and defining therapeutically homogeneous patient subclasses. It is an important approach in data-driven disease classification and subtyping. Acute…

Quantitative Methods · Quantitative Biology 2019-03-28 Eryu Xia , Xin Du , Jing Mei , Wen Sun , Suijun Tong , Zhiqing Kang , Jian Sheng , Jian Li , Changsheng Ma , Jianzeng Dong , Shaochun Li

Cardiovascular diseases (CVD) are the leading cause of death globally. Non-invasive, cost-effective imaging techniques play a crucial role in early detection and prevention of CVD. Optical coherence tomography (OCT) has gained recognition…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Cynthia Maldonado-Garcia , Rodrigo Bonazzola , Enzo Ferrante , Thomas H Julian , Panagiotis I Sergouniotis , Nishant Ravikumara , Alejandro F Frangi

Cellular composition prediction, i.e., predicting the presence and counts of different types of cells in the tumor microenvironment from a digitized image of a Hematoxylin and Eosin (H&E) stained tissue section can be used for various tasks…

Quantitative Methods · Quantitative Biology 2021-08-27 Muhammad Dawood , Kim Branson , Nasir M. Rajpoot , Fayyaz ul Amir Afsar Minhas

Purpose: To assess the early-phase of tear clearance rate (TCR) with anterior segment optical coherence tomography (OCT) and to determine the association between TCR and other clinical measures of the tear film in a group of young subjects…

Dysgraphia is a learning disorder that affects handwriting abilities, making it challenging for children to write legibly and consistently. Early detection and monitoring are crucial for providing timely support and interventions. This…

Computer Vision and Pattern Recognition · Computer Science 2024-11-22 Vydeki D , Divyansh Bhandari , Pranav Pratap Patil , Aarush Anand Kulkarni

Optical Chemical Structure Recognition (OCSR) is critical for converting 2D molecular diagrams from printed literature into machine-readable formats. While Vision-Language Models have shown promise in end-to-end OCR tasks, their direct…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Haocheng Tang , Xingyu Dang , Junmei Wang

Automated plankton image recognition is increasingly used in aquatic ecosystem monitoring, but deployed classifiers inevitably encounter unseen taxa and non-target particles. Open-set recognition methods are usually evaluated with…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Xi Chen , Eryuan Huang , Yingjun Xiao , Gang Fang

The integration of multi-omics data has emerged as a promising approach for gaining comprehensive insights into complex diseases such as cancer. This paper proposes a novel approach to identify cancer subtypes through the integration of…

Machine Learning · Computer Science 2023-12-06 Mark Peelen , Leila Bagheriye , Johan Kwisthout

In biological and medical research, scientists now routinely acquire microscopy images of hundreds of morphologically heterogeneous organoids and are then faced with the task of finding patterns in the image collection, i.e., subsets of…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Jannik Presberger , Rashmiparvathi Keshara , David Stein , Yung Hae Kim , Anne Grapin-Botton , Bjoern Andres

We present a machine learning method capable of accurately detecting chromosome abnormalities that cause blood cancers directly from microscope images of the metaphase stage of cell division. The pipeline is built on a series of fine-tuned…

Optical coherence tomography angiography (OCTA) is a non-invasive imaging technique widely used to study vascular structures and micro-circulation dynamics in the retina and choroid. OCTA has been widely used in clinics for diagnosing…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Kejie Chen , Guanbing Gao , Xiaochun Yang , Wenbo Wang , Jing Na

This paper presents our methodology and findings from three tasks across Optical Character Recognition (OCR) and Document Layout Analysis using advanced deep learning techniques. First, for the historical Hebrew fragments of the Dead Sea…

Computer Vision and Pattern Recognition · Computer Science 2025-08-15 Hylke Westerdijk , Ben Blankenborg , Khondoker Ittehadul Islam

Chromatin is a polymer complex of DNA and proteins that regulates gene expression. The three-dimensional structure and organization of chromatin controls DNA transcription and replication. High-throughput chromatin conformation capture…