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Local graph clustering is an important machine learning task that aims to find a well-connected cluster near a set of seed nodes. Recent results have revealed that incorporating higher order information significantly enhances the results of…
Clustering is a fundamental tool for analyzing large data sets. A rich body of work has been devoted to designing data-stream algorithms for the relevant optimization problems such as $k$-center, $k$-median, and $k$-means. Such algorithms…
While deep learning has seen many recent applications to drug discovery, most have focused on predicting activity or toxicity directly from chemical structure. Phenotypic changes exhibited in cellular images are also indications of the…
Deep learning based approaches to Computer Aided Diagnosis (CAD) typically pose the problem as an image classification (Normal or Abnormal) problem. These systems achieve high to very high accuracy in specific disease detection for which…
Accurate many-body treatments of condensed-phase systems are challenging because correlated solvers such as full configuration interaction (FCI) and the density matrix renormalization group (DMRG) scale exponentially with system size.…
Purpose: To develop an open-source, fully-automatic deep learning algorithm, DeepGPET, for choroid region segmentation in optical coherence tomography (OCT) data. Methods: We used a dataset of 715 OCT B-scans (82 subjects, 115 eyes) from 3…
Optical coherence tomography (OCT) is being increasingly adopted as a label-free and non-invasive technique for biomedical applications such as cancer and ocular disease diagnosis. Diagnostic information for these tissues is manifest in…
Cancer genomes exhibit a large number of different alterations that affect many genes in a diverse manner. It is widely believed that these alterations follow combinatorial patterns that have a strong connection with the underlying…
Ophthalmic diseases represent a significant global health issue, necessitating the use of advanced precise diagnostic tools. Optical Coherence Tomography (OCT) imagery which offers high-resolution cross-sectional images of the retina has…
Globular clusters (GCs) are powerful tracers of the galaxy assembly process, and have already been used to obtain a detailed picture of the progenitors of the Milky Way. Using the E-MOSAICS cosmological simulation of a (34.4 Mpc)$^3$ volume…
In several recent papers new gene-detection algorithms were proposed for detecting protein-coding regions without requiring learning dataset of already known genes. The fact that unsupervised gene-detection is possible closely connected to…
Deep graph clustering, which aims to reveal the underlying graph structure and divide the nodes into different clusters without human annotations, is a fundamental yet challenging task. However, we observed that the existing methods suffer…
Phylogenetic inference can potentially result in a more accurate tree using data from multiple loci. However, if the loci are incongruent--due to events such as incomplete lineage sorting or horizontal gene transfer--it can be misleading to…
In this study, we characterized 16 objects previously classified as faint or low contrast Galactic open clusters (OCs). We employed parameters associated to the OCs dynamical evolution: core ($r_c$), tidal ($r_t$) and half-mass ($r_{hm}$)…
Precise prognostic stratification of colorectal cancer (CRC) remains a major clinical challenge due to its high heterogeneity. The conventional TNM staging system is inadequate for personalized medicine. We aimed to develop and validate a…
Biological oscillations are periodic changes in various signaling processes crucial for the proper functioning of living organisms. These oscillations are modeled by ordinary differential equations, with coefficient variations leading to…
Magnetic Resonance Imaging (MRI) is widely used for screening and staging prostate cancer. However, many prostate cancers have subtle features which are not easily identifiable on MRI, resulting in missed diagnoses and alarming variability…
The grade of clear cell renal cell carcinoma (ccRCC) is a critical prognostic factor, making ccRCC nuclei grading a crucial task in RCC pathology analysis. Computer-aided nuclei grading aims to improve pathologists' work efficiency while…
Objectives To develop and validate a deep learning-based diagnostic model incorporating uncertainty estimation so as to facilitate radiologists in the preoperative differentiation of the pathological subtypes of renal cell carcinoma (RCC)…
Oral Squamous Cell Carcinoma (OSCC) is a prevalent and aggressive malignancy where deep learning-based computer-aided diagnosis and prognosis can enhance clinical assessments.However, existing publicly available OSCC datasets often suffer…