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Deep learning is currently the state-of-the-art for automated detection of referable diabetic retinopathy (DR) from color fundus photographs (CFP). While the general interest is put on improving results through methodological innovations,…

Image and Video Processing · Electrical Eng. & Systems 2022-10-10 Tomás Castilla , Marcela S. Martínez , Mercedes Leguía , Ignacio Larrabide , José Ignacio Orlando

In recent years, artificial intelligence has been increasingly applied in the field of medical imaging. Among these applications, fundus image analysis presents special challenges, including small lesion areas in certain fundus diseases and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Peiran Gu , Teng Yao , Mengshen He , Fuhao Duan , Feiyan Liu , RenYuan Peng , Bao Ge

Fundus images are essential for the early screening and detection of eye diseases. While deep learning models using fundus images have significantly advanced the diagnosis of multiple eye diseases, variations in images from different…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Qian Zeng , Le Zhang , Yipeng Liu , Ce Zhu , Fan Zhang

Significant advancements in AI-driven multimodal medical image diagnosis have led to substantial improvements in ophthalmic disease identification in recent years. However, acquiring paired multimodal ophthalmic images remains prohibitively…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Zhihao Zhao , Yinzheng Zhao , Junjie Yang , Xiangtong Yao , Quanmin Liang , Daniel Zapp , Kai Huang , Nassir Navab , M. Ali Nasseri

Glaucoma is a progressive eye disease that leads to optic nerve damage, causing irreversible vision loss if left untreated. Optical coherence tomography (OCT) has become a crucial tool for glaucoma diagnosis, offering high-resolution 3D…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Roshan Kenia , Anfei Li , Rishabh Srivastava , Kaveri A. Thakoor

Glaucoma is one of the primary causes of vision loss around the world, necessitating accurate and efficient detection methods. Traditional manual detection approaches have limitations in terms of cost, time, and subjectivity. Recent…

Image and Video Processing · Electrical Eng. & Systems 2023-11-03 Aized Amin Soofi , Fazal-e-Amin

Being the most commonly known neurodegeneration, Alzheimer's Disease (AD) is annually diagnosed in millions of patients. The present medical scenario still finds the exact diagnosis and classification of AD through neuroimaging data as a…

Image and Video Processing · Electrical Eng. & Systems 2025-03-19 Shravan Venkatraman , Pandiyaraju V , Abeshek A , Pavan Kumar S , Aravintakshan S A

Medical image classification is a core task in computer-aided diagnosis (CAD), playing a pivotal role in early disease detection, treatment planning, and patient prognosis assessment. In ophthalmic practice, fluorescein fundus angiography…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Zhuonan Wang , Wenjie Yan , Wenqiao Zhang , Xiaohui Song , Jian Ma , Ke Yao , Yibo Yu , Beng Chin Ooi

Automatic diagnosis techniques have evolved to identify age-related macular degeneration (AMD) by employing single modality Fundus images or optical coherence tomography (OCT). To classify ocular diseases, fundus and OCT images are the most…

Image and Video Processing · Electrical Eng. & Systems 2024-09-04 Pragya Gupta , Subhamoy Mandal , Debashree Guha , Debjani Chakraborty

Ocular conditions are a global concern and computational tools utilizing retinal fundus color photographs can aid in routine screening and management. Obtaining comprehensive and sufficiently sized datasets, however, is non-trivial for the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 P. Bilha Githinji , Keming Zhao , Jiantao Wang , Peiwu Qin

With the advancement of deep learning techniques, an increasing number of methods have been proposed for optic disc and cup (OD/OC) segmentation from the fundus images. Clinically, OD/OC segmentation is often annotated by multiple clinical…

Image and Video Processing · Electrical Eng. & Systems 2022-09-20 Junde Wu , Huihui Fang , Dalu Yang , Zhaowei Wang , Wenshuo Zhou , Fangxin Shang , Yehui Yang , Yanwu Xu

The development of automatic tools for early glaucoma diagnosis with color fundus photographs can significantly reduce the impact of this disease. However, current state-of-the-art solutions are not robust to real-world scenarios, providing…

Computer Vision and Pattern Recognition · Computer Science 2022-08-24 Teresa Araújo , Guilherme Aresta , Hrvoje Bogunovic

Diabetic Macular Edema (DME) is a leading cause of vision loss among patients with Diabetic Retinopathy (DR). While deep learning has shown promising results for automatically detecting this condition from fundus images, its application…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Franco Javier Arellano , José Ignacio Orlando

The automatic diagnosis of various retinal diseases from fundus images is important to support clinical decision-making. However, developing such automatic solutions is challenging due to the requirement of a large amount of human-annotated…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Xiaomeng Li , Mengyu Jia , Md Tauhidul Islam , Lequan Yu , Lei Xing

To investigate whether and to what extent central serous chorioretinopathy (CSC) depicted on color fundus photographs can be assessed using deep learning technology. We collected a total of 2,504 fundus images acquired on different…

Computer Vision and Pattern Recognition · Computer Science 2019-01-16 Yi Zhen , Hang Chen , Xu Zhang , Meng Liu , Xin Meng , Jian Zhang , Jiantao Pu

Fundus photography has been routinely used to document the presence and severity of various retinal degenerative diseases such as age-related macula degeneration, glaucoma, and diabetic retinopathy, for which the fovea, optic disc (OD), and…

Image and Video Processing · Electrical Eng. & Systems 2022-03-02 Huaqing He , Li Lin , Zhiyuan Cai , Xiaoying Tang

The rapid accessibility of portable and affordable retinal imaging devices has made early differential diagnosis easier. For example, color funduscopy imaging is readily available in remote villages, which can help to identify diseases like…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Khondker Fariha Hossain , Sharif Amit Kamran , Joshua Ong , Andrew G. Lee , Alireza Tavakkoli

Purpose: Automatic and accurate segmentation of fundus vessel images has become an essential prerequisite for computer-aided diagnosis of ophthalmic diseases such as diabetes mellitus. The task of high-precision retinal vessel segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Xiang Li , Mingsi Liu , Lixin Duan

Synthetic image generation has opened up new opportunities but has also created threats in regard to privacy, authenticity, and security. Detecting fake images is of paramount importance to prevent illegal activities, and previous research…

Computer Vision and Pattern Recognition · Computer Science 2023-02-27 Md Awsafur Rahman , Bishmoy Paul , Najibul Haque Sarker , Zaber Ibn Abdul Hakim , Shaikh Anowarul Fattah

The advent of handheld fundus imaging devices has made ophthalmologic diagnosis and disease screening more accessible, efficient, and cost-effective. However, images captured from these setups often suffer from artifacts such as flash…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Mathumetha Palani , Kavya Puthumana , Ayantika Das , Ganapathy Krishnamurthi