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WHO has declared that more than 2.2 billion people worldwide are suffering from visual disorders, such as media haze, glaucoma, and drusen. At least 1 billion of these cases could have been either prevented or successfully treated, yet they…

Image and Video Processing · Electrical Eng. & Systems 2024-05-30 Yavuz Selim Inan

Medical images are generally labeled by multiple experts before the final ground-truth labels are determined. Consensus or disagreement among experts regarding individual images reflects the gradeability and difficulty levels of the image.…

Computer Vision and Pattern Recognition · Computer Science 2020-07-30 Shuang Yu , Hong-Yu Zhou , Kai Ma , Cheng Bian , Chunyan Chu , Hanruo Liu , Yefeng Zheng

Diabetic retinopathy and diabetic macular edema are significant complications of diabetes that can lead to vision loss. Early detection through ultra-widefield fundus imaging enhances patient outcomes but presents challenges in image…

Image and Video Processing · Electrical Eng. & Systems 2024-09-20 Philippe Zhang , Pierre-Henri Conze , Mathieu Lamard , Gwenolé Quellec , Mostafa El Habib Daho

Comparison of microvascular circulation on fundoscopic images is a non-invasive clinical indication for the diagnosis and monitoring of diseases, such as diabetes and hypertensions. The differences between intra-patient images can be…

Image and Video Processing · Electrical Eng. & Systems 2019-12-24 Siming Bayer , Xia Zhong , Weilin Fu , Nishant Ravikumar , Andreas Maier

A well-known retinal disease that sends blurry visions to the affected patients is Macular Degeneration. This research is based on classifying the healthy and macular degeneration fundus by localizing the affected region of the fundus. A…

Image and Video Processing · Electrical Eng. & Systems 2024-05-03 Tahmim Hossain , Sagor Chandro Bakchy

A major cause of irreversible visual impairment is angle-closure glaucoma, which can be screened through imagery from Anterior Segment Optical Coherence Tomography (AS-OCT). Previous computational diagnostic techniques address this…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Huazhu Fu , Yanwu Xu , Stephen Lin , Damon Wing Kee Wong , Baskaran Mani , Meenakshi Mahesh , Tin Aung , Jiang Liu

The advancement of AI-assisted myopia screening necessitates the joint diagnosis of both-eye (OU) high myopia (HM) status and the prediction of axial length (AL). This clinical requirement introduces a complex mixed-type (binary-continuous)…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Chong Zhong , Yunhao Liu , Yang Li , Xiang Fu , Jin Yang , Danjuan Yang , Meiyan Li , Jinfeng Xu , Aiyi Liu , Alan H. Welsh , Xingtao Zhou , Bo Fu , Catherine C. Liu

Diabetic Retinopathy (DR) is a serious microvascular complication of diabetes, and one of the leading causes of vision loss worldwide. Although automated detection and grading, with Deep Learning (DL), can reduce the burden on…

Image and Video Processing · Electrical Eng. & Systems 2026-04-06 Shramana Dey , Zahir Khan , T. A. PramodKumar , B. Uma Shankar , Ashis K. Dhara , Ramachandran Rajalakshmi , Rajiv Raman , Sushmita Mitra

Refractive error, one of the leading cause of visual impairment, can be corrected by simple interventions like prescribing eyeglasses. We trained a deep learning algorithm to predict refractive error from the fundus photographs from…

Computer Vision and Pattern Recognition · Computer Science 2020-06-03 Avinash V. Varadarajan , Ryan Poplin , Katy Blumer , Christof Angermueller , Joe Ledsam , Reena Chopra , Pearse A. Keane , Greg S. Corrado , Lily Peng , Dale R. Webster

This paper presents a comparative analysis of deep learning strategies for detecting hypertensive retinopathy from fundus images, a central task in the HRDC challenge~\cite{qian2025hrdc}. We investigate three distinct approaches: a custom…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Yanqiao Zhu

Generative AI for automated glaucoma diagnostic report generation faces two predominant challenges: content redundancy in narrative outputs and inadequate highlighting of pathologically significant features including optic disc cupping,…

Computational Engineering, Finance, and Science · Computer Science 2025-10-14 Cheng Huang , Weizheng Xie , Zeyu Han , Tsengdar Lee , Karanjit Kooner , Jui-Ka Wang , Ning Zhang , Jia Zhang

In the last decades, large datasets of fundus photographs have been collected in diabetic retinopathy (DR) screening networks. Through deep learning, these datasets were used to train automatic detectors for DR and a few other frequent…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Gwenolé Quellec , Mathieu Lamard , Pierre-Henri Conze , Pascale Massin , Béatrice Cochener

The early diagnosis and screening of glaucoma are important for patients to receive treatment in time and maintain eyesight. Nowadays, deep learning (DL) based models have been successfully used for computer-aided diagnosis (CAD) of…

Image and Video Processing · Electrical Eng. & Systems 2021-08-10 Yiming Bao , Jun Wang , Tong Li , Linyan Wang , Jianwei Xu , Juan Ye , Dahong Qian

Ocular pathology detection from fundus images presents an important challenge on health care. In fact, each pathology has different severity stages that may be deduced by verifying the existence of specific lesions. Each lesion is…

Image and Video Processing · Electrical Eng. & Systems 2019-05-08 Yaroub Elloumi , Mohamed Akil , Henda Boudegga

The annotation of disease severity for medical image datasets often relies on collaborative decisions from multiple human graders. The intra-observer variability derived from individual differences always persists in this process, yet the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-03 Chi Liu , Zongyuan Ge , Mingguang He , Xiaotong Han

High-quality fundus images provide essential anatomical information for clinical screening and ophthalmic disease diagnosis. Yet, due to hardware limitations, operational variability, and patient compliance, fundus images often suffer from…

Optical Coherence Tomography (OCT) imaging plays an important role in glaucoma diagnosis in clinical practice. Early detection and timely treatment can prevent glaucoma patients from permanent vision loss. However, only a dearth of…

Computer Vision and Pattern Recognition · Computer Science 2019-07-31 Xi Wang , Hao Chen , Luyang Luo , An-ran Ran , Poemen P. Chan , Clement C. Tham , Carol Y. Cheung , Pheng-Ann Heng

Diabetic macular ischemia (DMI), marked by the loss of retinal capillaries in the macular area, contributes to vision impairment in patients with diabetes. Although color fundus photographs (CFPs), combined with artificial intelligence…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Qinghua He , Hongyang Jiang , Danqi Fang , Dawei Yang , Truong X. Nguyen , Anran Ran , Clement C. Tham , Simon K. H. Szeto , Sobha Sivaprasad , Carol Y. Cheung

Optical coherence tomography (OCT) based measurements of retinal layer thickness, such as the retinal nerve fibre layer (RNFL) and the ganglion cell with inner plexiform layer (GCIPL) are commonly used for the diagnosis and monitoring of…

Computer Vision and Pattern Recognition · Computer Science 2019-10-25 Stefan Maetschke , Bhavna Antony , Hiroshi Ishikawa , Gadi Wollstein , Joel S. Schuman , Rahil Garnavi

Optic disc (OD) and optic cup (OC) are regions of prominent clinical interest in a retinal fundus image. They are the primary indicators of a glaucomatous condition. With the advent and success of deep learning for healthcare research,…

Image and Video Processing · Electrical Eng. & Systems 2020-12-15 Aniketh Manjunath , Subramanya Jois , Chandra Sekhar Seelamantula