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Firth (1993, Biometrika) shows that the maximum Jeffreys' prior penalized likelihood estimator in logistic regression has asymptotic bias decreasing with the square of the number of observations when the number of parameters is fixed, which…

Methodology · Statistics 2024-09-09 Ioannis Kosmidis , Patrick Zietkiewicz

In logistic regression modeling, Firth's modified estimator is widely used to address the issue of data separation, which results in the nonexistence of the maximum likelihood estimate. Firth's modified estimator can be formulated as a…

Statistics Theory · Mathematics 2024-03-15 Mitsunori Ogawa , Yui Tomo

Firth-type logistic regression has become a standard approach for the analysis of binary outcomes with small samples. Whereas it reduces the bias in maximum likelihood estimates of coefficients, bias towards 1/2 is introduced in the…

Methodology · Statistics 2021-01-20 Rainer Puhr , Georg Heinze , Mariana Nold , Lara Lusa , Angelika Geroldinger

Penalization of the likelihood by Jeffreys' invariant prior, or by a positive power thereof, is shown to produce finite-valued maximum penalized likelihood estimates in a broad class of binomial generalized linear models. The class of…

Statistics Theory · Mathematics 2020-03-25 Ioannis Kosmidis , David Firth

Maximum likelihood estimation in logistic regression with mixed effects is known to often result in estimates on the boundary of the parameter space. Such estimates, which include infinite values for fixed effects and singular or infinite…

Methodology · Statistics 2023-02-03 Philipp Sterzinger , Ioannis Kosmidis

The widespread use of maximum Jeffreys'-prior penalized likelihood in binomial-response generalized linear models, and in logistic regression, in particular, are supported by the results of Kosmidis and Firth (2021, Biometrika), who show…

Methodology · Statistics 2024-06-10 Patrick Zietkiewicz , Ioannis Kosmidis

The estimation of categorical response models using bias-reducing adjusted score equations has seen extensive theoretical research and applied use. The resulting estimates have been found to have superior frequentist properties to what…

Methodology · Statistics 2022-01-25 Ioannis Kosmidis

For the estimation of cumulative link models for ordinal data, the bias-reducing adjusted score equations in \citet{firth:93} are obtained, whose solution ensures an estimator with smaller asymptotic bias than the maximum likelihood…

Methodology · Statistics 2018-02-16 Ioannis Kosmidis

We propose a penalized likelihood method that simultaneously fits the multinomial logistic regression model and combines subsets of the response categories. The penalty is non differentiable when pairs of columns in the optimization…

Methodology · Statistics 2017-05-11 Bradley S. Price , Charles J. Geyer , Adam J. Rothman

Positive and unlabelled learning is an important problem which arises naturally in many applications. The significant limitation of almost all existing methods lies in assuming that the propensity score function is constant (SCAR…

Machine Learning · Statistics 2023-11-01 Konrad Furmańczyk , Jan Mielniczuk , Wojciech Rejchel , Paweł Teisseyre

Optimization is widely used in statistics, and often efficiently delivers point estimates on useful spaces involving structural constraints or combinatorial structure. To quantify uncertainty, Gibbs posterior exponentiates the negative loss…

Methodology · Statistics 2025-07-23 Cheng Zeng , Eleni Dilma , Jason Xu , Leo L Duan

Logistic regression is the most commonly used method for constructing predictive models for binary responses. One significant drawback to this approach, however, is that the asymptotes of the logistic response function are fixed at 0 and 1,…

Methodology · Statistics 2026-02-09 Anthony Almudevar , Jacob Almudevar

Logistic regression is a fundamental and widely used statistical method for modeling binary outcomes based on covariates. However, the presence of missing data, particularly in settings involving hybrid covariates (a mix of discrete and…

Methodology · Statistics 2025-06-05 Mohamed Cherifi , Xujia Zhu , Mohammed Nabil El Korso , Ammar Mesloub

In this work, we introduce a modified (rescaled) likelihood for imbalanced logistic regression. This new approach makes easier the use of exponential priors and the computation of lasso regularization path. Precisely, we study a limiting…

Methodology · Statistics 2018-04-19 Vincent Runge

Inference for high-dimensional logistic regression models using penalized methods has been a challenging research problem. As an illustration, a major difficulty is the significant bias of the Lasso estimator, which limits its direct…

Methodology · Statistics 2024-10-29 Yuming Zhang , Stéphane Guerrier , Runze Li

Propensity score methods are widely used for estimating treatment effects from observational studies. A popular approach is to estimate propensity scores by maximum likelihood based on logistic regression, and then apply inverse probability…

Methodology · Statistics 2017-10-24 Zhiqiang Tan

Probit regression was first proposed by Bliss in 1934 to study mortality rates of insects. Since then, an extensive body of work has analyzed and used probit or related binary regression methods (such as logistic regression) in numerous…

Machine Learning · Statistics 2018-02-02 Andrew S. Lan , Mung Chiang , Christoph Studer

Data separation is a well-studied phenomenon that can cause problems in the estimation and inference from binary response models. Complete or quasi-complete separation occurs when there is a combination of regressors in the model whose…

Methodology · Statistics 2021-01-19 Susanne Köll , Ioannis Kosmidis , Christian Kleiber , Achim Zeileis

Logistic regression models are a popular and effective method to predict the probability of categorical response data. However inference for these models can become computationally prohibitive for large datasets. Here we adapt ideas from…

Methodology · Statistics 2020-08-25 Tom Whitaker , Boris Beranger , Scott A. Sisson

A procedure for asymptotic bias reduction of maximum likelihood estimates of generic estimands is developed. The estimator is realized as a plug-in estimator, where the parameter maximizes the penalized likelihood with a penalty function…

Statistics Theory · Mathematics 2024-03-26 Masayo Y. Hirose , Shuhei Mano
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